index mutID Chr Gname chr_gnam ref_id cluster GENE ARO_accession ARO_name ARO_description AMR_Gene_Family identity evalue q_start q_end query_coverage subject_coverage Drug_Class Resistance_Mechanism 1 M0006549 1111525849479399_bin.7__k141_122512 LNEHBNGB_00024 1111525849479399_bin.7__k141_122512__LNEHBNGB_00024 1111525849479399_bin.7__k141_122512 C1546 LNEHBNGB_00024 ARO:3007843 VRA-F VRA-F is an ABC transporter ATP-binding protein, or ATP-binding cassette. ATP-binding cassette (ABC) antibiotic efflux pump 79.4 1.24e-146 1 253 1.0 1 glycopeptide antibiotic antibiotic efflux 2 M0006550 1111525849479399_bin.7__k141_122512 LNEHBNGB_00024 1111525849479399_bin.7__k141_122512__LNEHBNGB_00024 1111525849479399_bin.7__k141_122512 C1546 LNEHBNGB_00024 ARO:3007843 VRA-F VRA-F is an ABC transporter ATP-binding protein, or ATP-binding cassette. ATP-binding cassette (ABC) antibiotic efflux pump 79.4 1.24e-146 1 253 1.0 1 glycopeptide antibiotic antibiotic efflux 3 M0006551 1111525849479399_bin.7__k141_122512 LNEHBNGB_00024 1111525849479399_bin.7__k141_122512__LNEHBNGB_00024 1111525849479399_bin.7__k141_122512 C1546 LNEHBNGB_00024 ARO:3007843 VRA-F VRA-F is an ABC transporter ATP-binding protein, or ATP-binding cassette. ATP-binding cassette (ABC) antibiotic efflux pump 79.4 1.24e-146 1 253 1.0 1 glycopeptide antibiotic antibiotic efflux 4 M0006552 1111525849479399_bin.7__k141_122512 LNEHBNGB_00024 1111525849479399_bin.7__k141_122512__LNEHBNGB_00024 1111525849479399_bin.7__k141_122512 C1546 LNEHBNGB_00024 ARO:3007843 VRA-F VRA-F is an ABC transporter ATP-binding protein, or ATP-binding cassette. ATP-binding cassette (ABC) antibiotic efflux pump 79.4 1.24e-146 1 253 1.0 1 glycopeptide antibiotic antibiotic efflux 5 M0006553 1111525849479399_bin.7__k141_122512 LNEHBNGB_00024 1111525849479399_bin.7__k141_122512__LNEHBNGB_00024 1111525849479399_bin.7__k141_122512 C1546 LNEHBNGB_00024 ARO:3007843 VRA-F VRA-F is an ABC transporter ATP-binding protein, or ATP-binding cassette. ATP-binding cassette (ABC) antibiotic efflux pump 79.4 1.24e-146 1 253 1.0 1 glycopeptide antibiotic antibiotic efflux 6 M0006554 1111525849479399_bin.7__k141_122512 LNEHBNGB_00024 1111525849479399_bin.7__k141_122512__LNEHBNGB_00024 1111525849479399_bin.7__k141_122512 C1546 LNEHBNGB_00024 ARO:3007843 VRA-F VRA-F is an ABC transporter ATP-binding protein, or ATP-binding cassette. ATP-binding cassette (ABC) antibiotic efflux pump 79.4 1.24e-146 1 253 1.0 1 glycopeptide antibiotic antibiotic efflux 7 M0006555 1111525849479399_bin.7__k141_122512 LNEHBNGB_00024 1111525849479399_bin.7__k141_122512__LNEHBNGB_00024 1111525849479399_bin.7__k141_122512 C1546 LNEHBNGB_00024 ARO:3007843 VRA-F VRA-F is an ABC transporter ATP-binding protein, or ATP-binding cassette. ATP-binding cassette (ABC) antibiotic efflux pump 79.4 1.24e-146 1 253 1.0 1 glycopeptide antibiotic antibiotic efflux 8 M0006556 1111525849479399_bin.7__k141_122512 LNEHBNGB_00024 1111525849479399_bin.7__k141_122512__LNEHBNGB_00024 1111525849479399_bin.7__k141_122512 C1546 LNEHBNGB_00024 ARO:3007843 VRA-F VRA-F is an ABC transporter ATP-binding protein, or ATP-binding cassette. ATP-binding cassette (ABC) antibiotic efflux pump 79.4 1.24e-146 1 253 1.0 1 glycopeptide antibiotic antibiotic efflux 9 M0006557 1111525849479399_bin.7__k141_122512 LNEHBNGB_00024 1111525849479399_bin.7__k141_122512__LNEHBNGB_00024 1111525849479399_bin.7__k141_122512 C1546 LNEHBNGB_00024 ARO:3007843 VRA-F VRA-F is an ABC transporter ATP-binding protein, or ATP-binding cassette. ATP-binding cassette (ABC) antibiotic efflux pump 79.4 1.24e-146 1 253 1.0 1 glycopeptide antibiotic antibiotic efflux 10 M0006558 1111525849479399_bin.7__k141_122512 LNEHBNGB_00024 1111525849479399_bin.7__k141_122512__LNEHBNGB_00024 1111525849479399_bin.7__k141_122512 C1546 LNEHBNGB_00024 ARO:3007843 VRA-F VRA-F is an ABC transporter ATP-binding protein, or ATP-binding cassette. ATP-binding cassette (ABC) antibiotic efflux pump 79.4 1.24e-146 1 253 1.0 1 glycopeptide antibiotic antibiotic efflux 11 M0006559 1111525849479399_bin.7__k141_122512 LNEHBNGB_00024 1111525849479399_bin.7__k141_122512__LNEHBNGB_00024 1111525849479399_bin.7__k141_122512 C1546 LNEHBNGB_00024 ARO:3007843 VRA-F VRA-F is an ABC transporter ATP-binding protein, or ATP-binding cassette. ATP-binding cassette (ABC) antibiotic efflux pump 79.4 1.24e-146 1 253 1.0 1 glycopeptide antibiotic antibiotic efflux 12 M0006560 1111525849479399_bin.7__k141_122512 LNEHBNGB_00024 1111525849479399_bin.7__k141_122512__LNEHBNGB_00024 1111525849479399_bin.7__k141_122512 C1546 LNEHBNGB_00024 ARO:3007843 VRA-F VRA-F is an ABC transporter ATP-binding protein, or ATP-binding cassette. ATP-binding cassette (ABC) antibiotic efflux pump 79.4 1.24e-146 1 253 1.0 1 glycopeptide antibiotic antibiotic efflux 13 M0006561 1111525849479399_bin.7__k141_122512 LNEHBNGB_00024 1111525849479399_bin.7__k141_122512__LNEHBNGB_00024 1111525849479399_bin.7__k141_122512 C1546 LNEHBNGB_00024 ARO:3007843 VRA-F VRA-F is an ABC transporter ATP-binding protein, or ATP-binding cassette. ATP-binding cassette (ABC) antibiotic efflux pump 79.4 1.24e-146 1 253 1.0 1 glycopeptide antibiotic antibiotic efflux 14 M0006562 1111525849479399_bin.7__k141_122512 LNEHBNGB_00024 1111525849479399_bin.7__k141_122512__LNEHBNGB_00024 1111525849479399_bin.7__k141_122512 C1546 LNEHBNGB_00024 ARO:3007843 VRA-F VRA-F is an ABC transporter ATP-binding protein, or ATP-binding cassette. ATP-binding cassette (ABC) antibiotic efflux pump 79.4 1.24e-146 1 253 1.0 1 glycopeptide antibiotic antibiotic efflux 15 M0006563 1111525849479399_bin.7__k141_122512 LNEHBNGB_00024 1111525849479399_bin.7__k141_122512__LNEHBNGB_00024 1111525849479399_bin.7__k141_122512 C1546 LNEHBNGB_00024 ARO:3007843 VRA-F VRA-F is an ABC transporter ATP-binding protein, or ATP-binding cassette. ATP-binding cassette (ABC) antibiotic efflux pump 79.4 1.24e-146 1 253 1.0 1 glycopeptide antibiotic antibiotic efflux 16 M0006564 1111525849479399_bin.7__k141_122512 LNEHBNGB_00024 1111525849479399_bin.7__k141_122512__LNEHBNGB_00024 1111525849479399_bin.7__k141_122512 C1546 LNEHBNGB_00024 ARO:3007843 VRA-F VRA-F is an ABC transporter ATP-binding protein, or ATP-binding cassette. ATP-binding cassette (ABC) antibiotic efflux pump 79.4 1.24e-146 1 253 1.0 1 glycopeptide antibiotic antibiotic efflux 17 M0006565 1111525849479399_bin.7__k141_122512 LNEHBNGB_00024 1111525849479399_bin.7__k141_122512__LNEHBNGB_00024 1111525849479399_bin.7__k141_122512 C1546 LNEHBNGB_00024 ARO:3007843 VRA-F VRA-F is an ABC transporter ATP-binding protein, or ATP-binding cassette. ATP-binding cassette (ABC) antibiotic efflux pump 79.4 1.24e-146 1 253 1.0 1 glycopeptide antibiotic antibiotic efflux 18 M0006566 1111525849479399_bin.7__k141_122512 LNEHBNGB_00024 1111525849479399_bin.7__k141_122512__LNEHBNGB_00024 1111525849479399_bin.7__k141_122512 C1546 LNEHBNGB_00024 ARO:3007843 VRA-F VRA-F is an ABC transporter ATP-binding protein, or ATP-binding cassette. ATP-binding cassette (ABC) antibiotic efflux pump 79.4 1.24e-146 1 253 1.0 1 glycopeptide antibiotic antibiotic efflux 19 M0006971 1111525849479399_bin.7__k141_122512 LNEHBNGB_00024 1111525849479399_bin.7__k141_122512__LNEHBNGB_00024 1111525849479399_bin.7__k141_122512 C1546 LNEHBNGB_00024 ARO:3007843 VRA-F VRA-F is an ABC transporter ATP-binding protein, or ATP-binding cassette. ATP-binding cassette (ABC) antibiotic efflux pump 79.4 1.24e-146 1 253 1.0 1 glycopeptide antibiotic antibiotic efflux 20 M0007074 1111525849479399_bin.7__k141_122512 LNEHBNGB_00024 1111525849479399_bin.7__k141_122512__LNEHBNGB_00024 1111525849479399_bin.7__k141_122512 C1546 LNEHBNGB_00024 ARO:3007843 VRA-F VRA-F is an ABC transporter ATP-binding protein, or ATP-binding cassette. ATP-binding cassette (ABC) antibiotic efflux pump 79.4 1.24e-146 1 253 1.0 1 glycopeptide antibiotic antibiotic efflux 21 M0007075 1111525849479399_bin.7__k141_122512 LNEHBNGB_00024 1111525849479399_bin.7__k141_122512__LNEHBNGB_00024 1111525849479399_bin.7__k141_122512 C1546 LNEHBNGB_00024 ARO:3007843 VRA-F VRA-F is an ABC transporter ATP-binding protein, or ATP-binding cassette. ATP-binding cassette (ABC) antibiotic efflux pump 79.4 1.24e-146 1 253 1.0 1 glycopeptide antibiotic antibiotic efflux 22 M0007076 1111525849479399_bin.7__k141_122512 LNEHBNGB_00024 1111525849479399_bin.7__k141_122512__LNEHBNGB_00024 1111525849479399_bin.7__k141_122512 C1546 LNEHBNGB_00024 ARO:3007843 VRA-F VRA-F is an ABC transporter ATP-binding protein, or ATP-binding cassette. ATP-binding cassette (ABC) antibiotic efflux pump 79.4 1.24e-146 1 253 1.0 1 glycopeptide antibiotic antibiotic efflux 23 M0007077 1111525849479399_bin.7__k141_122512 LNEHBNGB_00024 1111525849479399_bin.7__k141_122512__LNEHBNGB_00024 1111525849479399_bin.7__k141_122512 C1546 LNEHBNGB_00024 ARO:3007843 VRA-F VRA-F is an ABC transporter ATP-binding protein, or ATP-binding cassette. ATP-binding cassette (ABC) antibiotic efflux pump 79.4 1.24e-146 1 253 1.0 1 glycopeptide antibiotic antibiotic efflux 24 M0007185 1111525849479399_bin.7__k141_122512 LNEHBNGB_00024 1111525849479399_bin.7__k141_122512__LNEHBNGB_00024 1111525849479399_bin.7__k141_122512 C1546 LNEHBNGB_00024 ARO:3007843 VRA-F VRA-F is an ABC transporter ATP-binding protein, or ATP-binding cassette. ATP-binding cassette (ABC) antibiotic efflux pump 79.4 1.24e-146 1 253 1.0 1 glycopeptide antibiotic antibiotic efflux 25 M0007186 1111525849479399_bin.7__k141_122512 LNEHBNGB_00024 1111525849479399_bin.7__k141_122512__LNEHBNGB_00024 1111525849479399_bin.7__k141_122512 C1546 LNEHBNGB_00024 ARO:3007843 VRA-F VRA-F is an ABC transporter ATP-binding protein, or ATP-binding cassette. ATP-binding cassette (ABC) antibiotic efflux pump 79.4 1.24e-146 1 253 1.0 1 glycopeptide antibiotic antibiotic efflux 26 M0008488 1111525849481321_bin.4__k141_87464 DFKAHJCB_00011 1111525849481321_bin.4__k141_87464__DFKAHJCB_00011 1111525849481321_bin.4__k141_87464 C1609 DFKAHJCB_00011 ARO:3003395 Mycobacterium tuberculosis rpsL mutations conferring resistance to Streptomycin Ribosomal protein S12 stabilizes the highly conserved pseudoknot structure formed by 16S rRNA. Amino acid substitutions in RpsL affect the higher-order structure of 16S rRNA and confer streptomycin resistance by disrupting interactions between 16S rRNA and streptomycin. antibiotic-resistant rpsL 70.7 4.73e-56 1 123 1.0 0.991935483870968 aminoglycoside antibiotic antibiotic target alteration 27 M0008494 1111525849481321_bin.4__k141_87464 DFKAHJCB_00014 1111525849481321_bin.4__k141_87464__DFKAHJCB_00014 1111525849481321_bin.4__k141_87464 C1609 DFKAHJCB_00014 ARO:3003368 Escherichia coli EF-Tu mutants conferring resistance to kirromycin Sequence variants of Escherichia coli elongation factor Tu that confer resistance to kirromycin. elfamycin resistant EF-Tu 80.3 1.19e-238 1 395 0.9974747474747475 1.00253807106599 elfamycin antibiotic antibiotic target alteration 28 M0008497 1111525849481321_bin.4__k141_87464 DFKAHJCB_00014 1111525849481321_bin.4__k141_87464__DFKAHJCB_00014 1111525849481321_bin.4__k141_87464 C1609 DFKAHJCB_00014 ARO:3003368 Escherichia coli EF-Tu mutants conferring resistance to kirromycin Sequence variants of Escherichia coli elongation factor Tu that confer resistance to kirromycin. elfamycin resistant EF-Tu 80.3 1.19e-238 1 395 0.9974747474747475 1.00253807106599 elfamycin antibiotic antibiotic target alteration 29 M0008922 1111525849481828_bin.7__k141_638260 JPGDOPCJ_00014 1111525849481828_bin.7__k141_638260__JPGDOPCJ_00014 1111525849481828_bin.7__k141_638260 C1625 JPGDOPCJ_00014 ARO:3000378 MexB MexB is the inner membrane multidrug exporter of the efflux complex MexAB-OprM. resistance-nodulation-cell division (RND) antibiotic efflux pump 78.4 0 1 1042 0.9933333333333333 0.997131931166348 macrolide antibiotic antibiotic efflux 30 M0010111 1111525849484910_bin.15__k141_136913 AMMFCDDB_00003 1111525849484910_bin.15__k141_136913__AMMFCDDB_00003 1111525849484910_bin.15__k141_136913 C1656 AMMFCDDB_00003 ARO:3000804 MexF MexF is the multidrug inner membrane transporter of the MexEF-OprN complex. mexF corresponds to 2 loci in Pseudomonas aeruginosa PAO1 (gene name: mexF/mexB) and 4 loci in Pseudomonas aeruginosa LESB58 (gene name: mexD/mexB). resistance-nodulation-cell division (RND) antibiotic efflux pump 89.2 0 1 1049 0.9924457034938622 0.989642184557439 fluoroquinolone antibiotic antibiotic efflux 31 M0010112 1111525849484910_bin.15__k141_136913 AMMFCDDB_00003 1111525849484910_bin.15__k141_136913__AMMFCDDB_00003 1111525849484910_bin.15__k141_136913 C1656 AMMFCDDB_00003 ARO:3000804 MexF MexF is the multidrug inner membrane transporter of the MexEF-OprN complex. mexF corresponds to 2 loci in Pseudomonas aeruginosa PAO1 (gene name: mexF/mexB) and 4 loci in Pseudomonas aeruginosa LESB58 (gene name: mexD/mexB). resistance-nodulation-cell division (RND) antibiotic efflux pump 89.2 0 1 1049 0.9924457034938622 0.989642184557439 fluoroquinolone antibiotic antibiotic efflux 32 M0010113 1111525849484910_bin.15__k141_136913 AMMFCDDB_00003 1111525849484910_bin.15__k141_136913__AMMFCDDB_00003 1111525849484910_bin.15__k141_136913 C1656 AMMFCDDB_00003 ARO:3000804 MexF MexF is the multidrug inner membrane transporter of the MexEF-OprN complex. mexF corresponds to 2 loci in Pseudomonas aeruginosa PAO1 (gene name: mexF/mexB) and 4 loci in Pseudomonas aeruginosa LESB58 (gene name: mexD/mexB). resistance-nodulation-cell division (RND) antibiotic efflux pump 89.2 0 1 1049 0.9924457034938622 0.989642184557439 fluoroquinolone antibiotic antibiotic efflux 33 M0010114 1111525849484910_bin.15__k141_136913 AMMFCDDB_00003 1111525849484910_bin.15__k141_136913__AMMFCDDB_00003 1111525849484910_bin.15__k141_136913 C1656 AMMFCDDB_00003 ARO:3000804 MexF MexF is the multidrug inner membrane transporter of the MexEF-OprN complex. mexF corresponds to 2 loci in Pseudomonas aeruginosa PAO1 (gene name: mexF/mexB) and 4 loci in Pseudomonas aeruginosa LESB58 (gene name: mexD/mexB). resistance-nodulation-cell division (RND) antibiotic efflux pump 89.2 0 1 1049 0.9924457034938622 0.989642184557439 fluoroquinolone antibiotic antibiotic efflux 34 M0010115 1111525849484910_bin.15__k141_136913 AMMFCDDB_00003 1111525849484910_bin.15__k141_136913__AMMFCDDB_00003 1111525849484910_bin.15__k141_136913 C1656 AMMFCDDB_00003 ARO:3000804 MexF MexF is the multidrug inner membrane transporter of the MexEF-OprN complex. mexF corresponds to 2 loci in Pseudomonas aeruginosa PAO1 (gene name: mexF/mexB) and 4 loci in Pseudomonas aeruginosa LESB58 (gene name: mexD/mexB). resistance-nodulation-cell division (RND) antibiotic efflux pump 89.2 0 1 1049 0.9924457034938622 0.989642184557439 fluoroquinolone antibiotic antibiotic efflux 35 M0010116 1111525849484910_bin.15__k141_136913 AMMFCDDB_00003 1111525849484910_bin.15__k141_136913__AMMFCDDB_00003 1111525849484910_bin.15__k141_136913 C1656 AMMFCDDB_00003 ARO:3000804 MexF MexF is the multidrug inner membrane transporter of the MexEF-OprN complex. mexF corresponds to 2 loci in Pseudomonas aeruginosa PAO1 (gene name: mexF/mexB) and 4 loci in Pseudomonas aeruginosa LESB58 (gene name: mexD/mexB). resistance-nodulation-cell division (RND) antibiotic efflux pump 89.2 0 1 1049 0.9924457034938622 0.989642184557439 fluoroquinolone antibiotic antibiotic efflux 36 M0010117 1111525849484910_bin.15__k141_136913 AMMFCDDB_00003 1111525849484910_bin.15__k141_136913__AMMFCDDB_00003 1111525849484910_bin.15__k141_136913 C1656 AMMFCDDB_00003 ARO:3000804 MexF MexF is the multidrug inner membrane transporter of the MexEF-OprN complex. mexF corresponds to 2 loci in Pseudomonas aeruginosa PAO1 (gene name: mexF/mexB) and 4 loci in Pseudomonas aeruginosa LESB58 (gene name: mexD/mexB). resistance-nodulation-cell division (RND) antibiotic efflux pump 89.2 0 1 1049 0.9924457034938622 0.989642184557439 fluoroquinolone antibiotic antibiotic efflux 37 M0010118 1111525849484910_bin.15__k141_136913 AMMFCDDB_00003 1111525849484910_bin.15__k141_136913__AMMFCDDB_00003 1111525849484910_bin.15__k141_136913 C1656 AMMFCDDB_00003 ARO:3000804 MexF MexF is the multidrug inner membrane transporter of the MexEF-OprN complex. mexF corresponds to 2 loci in Pseudomonas aeruginosa PAO1 (gene name: mexF/mexB) and 4 loci in Pseudomonas aeruginosa LESB58 (gene name: mexD/mexB). resistance-nodulation-cell division (RND) antibiotic efflux pump 89.2 0 1 1049 0.9924457034938622 0.989642184557439 fluoroquinolone antibiotic antibiotic efflux 38 M0010119 1111525849484910_bin.15__k141_136913 AMMFCDDB_00003 1111525849484910_bin.15__k141_136913__AMMFCDDB_00003 1111525849484910_bin.15__k141_136913 C1656 AMMFCDDB_00003 ARO:3000804 MexF MexF is the multidrug inner membrane transporter of the MexEF-OprN complex. mexF corresponds to 2 loci in Pseudomonas aeruginosa PAO1 (gene name: mexF/mexB) and 4 loci in Pseudomonas aeruginosa LESB58 (gene name: mexD/mexB). resistance-nodulation-cell division (RND) antibiotic efflux pump 89.2 0 1 1049 0.9924457034938622 0.989642184557439 fluoroquinolone antibiotic antibiotic efflux 39 M0010120 1111525849484910_bin.15__k141_136913 AMMFCDDB_00003 1111525849484910_bin.15__k141_136913__AMMFCDDB_00003 1111525849484910_bin.15__k141_136913 C1656 AMMFCDDB_00003 ARO:3000804 MexF MexF is the multidrug inner membrane transporter of the MexEF-OprN complex. mexF corresponds to 2 loci in Pseudomonas aeruginosa PAO1 (gene name: mexF/mexB) and 4 loci in Pseudomonas aeruginosa LESB58 (gene name: mexD/mexB). resistance-nodulation-cell division (RND) antibiotic efflux pump 89.2 0 1 1049 0.9924457034938622 0.989642184557439 fluoroquinolone antibiotic antibiotic efflux 40 M0010121 1111525849484910_bin.15__k141_136913 AMMFCDDB_00003 1111525849484910_bin.15__k141_136913__AMMFCDDB_00003 1111525849484910_bin.15__k141_136913 C1656 AMMFCDDB_00003 ARO:3000804 MexF MexF is the multidrug inner membrane transporter of the MexEF-OprN complex. mexF corresponds to 2 loci in Pseudomonas aeruginosa PAO1 (gene name: mexF/mexB) and 4 loci in Pseudomonas aeruginosa LESB58 (gene name: mexD/mexB). resistance-nodulation-cell division (RND) antibiotic efflux pump 89.2 0 1 1049 0.9924457034938622 0.989642184557439 fluoroquinolone antibiotic antibiotic efflux 41 M0010122 1111525849484910_bin.15__k141_136913 AMMFCDDB_00003 1111525849484910_bin.15__k141_136913__AMMFCDDB_00003 1111525849484910_bin.15__k141_136913 C1656 AMMFCDDB_00003 ARO:3000804 MexF MexF is the multidrug inner membrane transporter of the MexEF-OprN complex. mexF corresponds to 2 loci in Pseudomonas aeruginosa PAO1 (gene name: mexF/mexB) and 4 loci in Pseudomonas aeruginosa LESB58 (gene name: mexD/mexB). resistance-nodulation-cell division (RND) antibiotic efflux pump 89.2 0 1 1049 0.9924457034938622 0.989642184557439 fluoroquinolone antibiotic antibiotic efflux 42 M0010123 1111525849484910_bin.15__k141_136913 AMMFCDDB_00003 1111525849484910_bin.15__k141_136913__AMMFCDDB_00003 1111525849484910_bin.15__k141_136913 C1656 AMMFCDDB_00003 ARO:3000804 MexF MexF is the multidrug inner membrane transporter of the MexEF-OprN complex. mexF corresponds to 2 loci in Pseudomonas aeruginosa PAO1 (gene name: mexF/mexB) and 4 loci in Pseudomonas aeruginosa LESB58 (gene name: mexD/mexB). resistance-nodulation-cell division (RND) antibiotic efflux pump 89.2 0 1 1049 0.9924457034938622 0.989642184557439 fluoroquinolone antibiotic antibiotic efflux 43 M0010124 1111525849484910_bin.15__k141_136913 AMMFCDDB_00003 1111525849484910_bin.15__k141_136913__AMMFCDDB_00003 1111525849484910_bin.15__k141_136913 C1656 AMMFCDDB_00003 ARO:3000804 MexF MexF is the multidrug inner membrane transporter of the MexEF-OprN complex. mexF corresponds to 2 loci in Pseudomonas aeruginosa PAO1 (gene name: mexF/mexB) and 4 loci in Pseudomonas aeruginosa LESB58 (gene name: mexD/mexB). resistance-nodulation-cell division (RND) antibiotic efflux pump 89.2 0 1 1049 0.9924457034938622 0.989642184557439 fluoroquinolone antibiotic antibiotic efflux 44 M0010125 1111525849484910_bin.15__k141_136913 AMMFCDDB_00004 1111525849484910_bin.15__k141_136913__AMMFCDDB_00004 1111525849484910_bin.15__k141_136913 C1656 AMMFCDDB_00004 ARO:3000805 OprN OprN is the outer membrane channel component of the MexEF-OprN multidrug efflux complex. resistance-nodulation-cell division (RND) antibiotic efflux pump 79.2 5.28e-246 14 465 0.9576271186440678 0.957627118644068 fluoroquinolone antibiotic antibiotic efflux 45 M0010134 1111525849484910_bin.15__k141_136913 AMMFCDDB_00003 1111525849484910_bin.15__k141_136913__AMMFCDDB_00003 1111525849484910_bin.15__k141_136913 C1656 AMMFCDDB_00003 ARO:3000804 MexF MexF is the multidrug inner membrane transporter of the MexEF-OprN complex. mexF corresponds to 2 loci in Pseudomonas aeruginosa PAO1 (gene name: mexF/mexB) and 4 loci in Pseudomonas aeruginosa LESB58 (gene name: mexD/mexB). resistance-nodulation-cell division (RND) antibiotic efflux pump 89.2 0 1 1049 0.9924457034938622 0.989642184557439 fluoroquinolone antibiotic antibiotic efflux 46 M0010135 1111525849484910_bin.15__k141_136913 AMMFCDDB_00003 1111525849484910_bin.15__k141_136913__AMMFCDDB_00003 1111525849484910_bin.15__k141_136913 C1656 AMMFCDDB_00003 ARO:3000804 MexF MexF is the multidrug inner membrane transporter of the MexEF-OprN complex. mexF corresponds to 2 loci in Pseudomonas aeruginosa PAO1 (gene name: mexF/mexB) and 4 loci in Pseudomonas aeruginosa LESB58 (gene name: mexD/mexB). resistance-nodulation-cell division (RND) antibiotic efflux pump 89.2 0 1 1049 0.9924457034938622 0.989642184557439 fluoroquinolone antibiotic antibiotic efflux 47 M0010136 1111525849484910_bin.15__k141_136913 AMMFCDDB_00003 1111525849484910_bin.15__k141_136913__AMMFCDDB_00003 1111525849484910_bin.15__k141_136913 C1656 AMMFCDDB_00003 ARO:3000804 MexF MexF is the multidrug inner membrane transporter of the MexEF-OprN complex. mexF corresponds to 2 loci in Pseudomonas aeruginosa PAO1 (gene name: mexF/mexB) and 4 loci in Pseudomonas aeruginosa LESB58 (gene name: mexD/mexB). resistance-nodulation-cell division (RND) antibiotic efflux pump 89.2 0 1 1049 0.9924457034938622 0.989642184557439 fluoroquinolone antibiotic antibiotic efflux 48 M0010150 1111525849484910_bin.15__k141_136913 AMMFCDDB_00003 1111525849484910_bin.15__k141_136913__AMMFCDDB_00003 1111525849484910_bin.15__k141_136913 C1656 AMMFCDDB_00003 ARO:3000804 MexF MexF is the multidrug inner membrane transporter of the MexEF-OprN complex. mexF corresponds to 2 loci in Pseudomonas aeruginosa PAO1 (gene name: mexF/mexB) and 4 loci in Pseudomonas aeruginosa LESB58 (gene name: mexD/mexB). resistance-nodulation-cell division (RND) antibiotic efflux pump 89.2 0 1 1049 0.9924457034938622 0.989642184557439 fluoroquinolone antibiotic antibiotic efflux 49 M0010151 1111525849484910_bin.15__k141_136913 AMMFCDDB_00003 1111525849484910_bin.15__k141_136913__AMMFCDDB_00003 1111525849484910_bin.15__k141_136913 C1656 AMMFCDDB_00003 ARO:3000804 MexF MexF is the multidrug inner membrane transporter of the MexEF-OprN complex. mexF corresponds to 2 loci in Pseudomonas aeruginosa PAO1 (gene name: mexF/mexB) and 4 loci in Pseudomonas aeruginosa LESB58 (gene name: mexD/mexB). resistance-nodulation-cell division (RND) antibiotic efflux pump 89.2 0 1 1049 0.9924457034938622 0.989642184557439 fluoroquinolone antibiotic antibiotic efflux 50 M0010165 1111525849484910_bin.15__k141_136913 AMMFCDDB_00003 1111525849484910_bin.15__k141_136913__AMMFCDDB_00003 1111525849484910_bin.15__k141_136913 C1656 AMMFCDDB_00003 ARO:3000804 MexF MexF is the multidrug inner membrane transporter of the MexEF-OprN complex. mexF corresponds to 2 loci in Pseudomonas aeruginosa PAO1 (gene name: mexF/mexB) and 4 loci in Pseudomonas aeruginosa LESB58 (gene name: mexD/mexB). resistance-nodulation-cell division (RND) antibiotic efflux pump 89.2 0 1 1049 0.9924457034938622 0.989642184557439 fluoroquinolone antibiotic antibiotic efflux 51 M0010166 1111525849484910_bin.15__k141_136913 AMMFCDDB_00003 1111525849484910_bin.15__k141_136913__AMMFCDDB_00003 1111525849484910_bin.15__k141_136913 C1656 AMMFCDDB_00003 ARO:3000804 MexF MexF is the multidrug inner membrane transporter of the MexEF-OprN complex. mexF corresponds to 2 loci in Pseudomonas aeruginosa PAO1 (gene name: mexF/mexB) and 4 loci in Pseudomonas aeruginosa LESB58 (gene name: mexD/mexB). resistance-nodulation-cell division (RND) antibiotic efflux pump 89.2 0 1 1049 0.9924457034938622 0.989642184557439 fluoroquinolone antibiotic antibiotic efflux 52 M0010169 1111525849484910_bin.15__k141_136913 AMMFCDDB_00004 1111525849484910_bin.15__k141_136913__AMMFCDDB_00004 1111525849484910_bin.15__k141_136913 C1656 AMMFCDDB_00004 ARO:3000805 OprN OprN is the outer membrane channel component of the MexEF-OprN multidrug efflux complex. resistance-nodulation-cell division (RND) antibiotic efflux pump 79.2 5.28e-246 14 465 0.9576271186440678 0.957627118644068 fluoroquinolone antibiotic antibiotic efflux 53 M0010174 1111525849484910_bin.15__k141_136913 AMMFCDDB_00004 1111525849484910_bin.15__k141_136913__AMMFCDDB_00004 1111525849484910_bin.15__k141_136913 C1656 AMMFCDDB_00004 ARO:3000805 OprN OprN is the outer membrane channel component of the MexEF-OprN multidrug efflux complex. resistance-nodulation-cell division (RND) antibiotic efflux pump 79.2 5.28e-246 14 465 0.9576271186440678 0.957627118644068 fluoroquinolone antibiotic antibiotic efflux 54 M0010184 1111525849484910_bin.15__k141_136913 AMMFCDDB_00003 1111525849484910_bin.15__k141_136913__AMMFCDDB_00003 1111525849484910_bin.15__k141_136913 C1656 AMMFCDDB_00003 ARO:3000804 MexF MexF is the multidrug inner membrane transporter of the MexEF-OprN complex. mexF corresponds to 2 loci in Pseudomonas aeruginosa PAO1 (gene name: mexF/mexB) and 4 loci in Pseudomonas aeruginosa LESB58 (gene name: mexD/mexB). resistance-nodulation-cell division (RND) antibiotic efflux pump 89.2 0 1 1049 0.9924457034938622 0.989642184557439 fluoroquinolone antibiotic antibiotic efflux 55 M0010185 1111525849484910_bin.15__k141_136913 AMMFCDDB_00003 1111525849484910_bin.15__k141_136913__AMMFCDDB_00003 1111525849484910_bin.15__k141_136913 C1656 AMMFCDDB_00003 ARO:3000804 MexF MexF is the multidrug inner membrane transporter of the MexEF-OprN complex. mexF corresponds to 2 loci in Pseudomonas aeruginosa PAO1 (gene name: mexF/mexB) and 4 loci in Pseudomonas aeruginosa LESB58 (gene name: mexD/mexB). resistance-nodulation-cell division (RND) antibiotic efflux pump 89.2 0 1 1049 0.9924457034938622 0.989642184557439 fluoroquinolone antibiotic antibiotic efflux 56 M0010186 1111525849484910_bin.15__k141_136913 AMMFCDDB_00003 1111525849484910_bin.15__k141_136913__AMMFCDDB_00003 1111525849484910_bin.15__k141_136913 C1656 AMMFCDDB_00003 ARO:3000804 MexF MexF is the multidrug inner membrane transporter of the MexEF-OprN complex. mexF corresponds to 2 loci in Pseudomonas aeruginosa PAO1 (gene name: mexF/mexB) and 4 loci in Pseudomonas aeruginosa LESB58 (gene name: mexD/mexB). resistance-nodulation-cell division (RND) antibiotic efflux pump 89.2 0 1 1049 0.9924457034938622 0.989642184557439 fluoroquinolone antibiotic antibiotic efflux 57 M0010187 1111525849484910_bin.15__k141_136913 AMMFCDDB_00003 1111525849484910_bin.15__k141_136913__AMMFCDDB_00003 1111525849484910_bin.15__k141_136913 C1656 AMMFCDDB_00003 ARO:3000804 MexF MexF is the multidrug inner membrane transporter of the MexEF-OprN complex. mexF corresponds to 2 loci in Pseudomonas aeruginosa PAO1 (gene name: mexF/mexB) and 4 loci in Pseudomonas aeruginosa LESB58 (gene name: mexD/mexB). resistance-nodulation-cell division (RND) antibiotic efflux pump 89.2 0 1 1049 0.9924457034938622 0.989642184557439 fluoroquinolone antibiotic antibiotic efflux 58 M0010188 1111525849484910_bin.15__k141_136913 AMMFCDDB_00003 1111525849484910_bin.15__k141_136913__AMMFCDDB_00003 1111525849484910_bin.15__k141_136913 C1656 AMMFCDDB_00003 ARO:3000804 MexF MexF is the multidrug inner membrane transporter of the MexEF-OprN complex. mexF corresponds to 2 loci in Pseudomonas aeruginosa PAO1 (gene name: mexF/mexB) and 4 loci in Pseudomonas aeruginosa LESB58 (gene name: mexD/mexB). resistance-nodulation-cell division (RND) antibiotic efflux pump 89.2 0 1 1049 0.9924457034938622 0.989642184557439 fluoroquinolone antibiotic antibiotic efflux 59 M0010189 1111525849484910_bin.15__k141_136913 AMMFCDDB_00003 1111525849484910_bin.15__k141_136913__AMMFCDDB_00003 1111525849484910_bin.15__k141_136913 C1656 AMMFCDDB_00003 ARO:3000804 MexF MexF is the multidrug inner membrane transporter of the MexEF-OprN complex. mexF corresponds to 2 loci in Pseudomonas aeruginosa PAO1 (gene name: mexF/mexB) and 4 loci in Pseudomonas aeruginosa LESB58 (gene name: mexD/mexB). resistance-nodulation-cell division (RND) antibiotic efflux pump 89.2 0 1 1049 0.9924457034938622 0.989642184557439 fluoroquinolone antibiotic antibiotic efflux 60 M0010191 1111525849484910_bin.15__k141_136913 AMMFCDDB_00003 1111525849484910_bin.15__k141_136913__AMMFCDDB_00003 1111525849484910_bin.15__k141_136913 C1656 AMMFCDDB_00003 ARO:3000804 MexF MexF is the multidrug inner membrane transporter of the MexEF-OprN complex. mexF corresponds to 2 loci in Pseudomonas aeruginosa PAO1 (gene name: mexF/mexB) and 4 loci in Pseudomonas aeruginosa LESB58 (gene name: mexD/mexB). resistance-nodulation-cell division (RND) antibiotic efflux pump 89.2 0 1 1049 0.9924457034938622 0.989642184557439 fluoroquinolone antibiotic antibiotic efflux 61 M0010192 1111525849484910_bin.15__k141_136913 AMMFCDDB_00003 1111525849484910_bin.15__k141_136913__AMMFCDDB_00003 1111525849484910_bin.15__k141_136913 C1656 AMMFCDDB_00003 ARO:3000804 MexF MexF is the multidrug inner membrane transporter of the MexEF-OprN complex. mexF corresponds to 2 loci in Pseudomonas aeruginosa PAO1 (gene name: mexF/mexB) and 4 loci in Pseudomonas aeruginosa LESB58 (gene name: mexD/mexB). resistance-nodulation-cell division (RND) antibiotic efflux pump 89.2 0 1 1049 0.9924457034938622 0.989642184557439 fluoroquinolone antibiotic antibiotic efflux 62 M0010193 1111525849484910_bin.15__k141_136913 AMMFCDDB_00003 1111525849484910_bin.15__k141_136913__AMMFCDDB_00003 1111525849484910_bin.15__k141_136913 C1656 AMMFCDDB_00003 ARO:3000804 MexF MexF is the multidrug inner membrane transporter of the MexEF-OprN complex. mexF corresponds to 2 loci in Pseudomonas aeruginosa PAO1 (gene name: mexF/mexB) and 4 loci in Pseudomonas aeruginosa LESB58 (gene name: mexD/mexB). resistance-nodulation-cell division (RND) antibiotic efflux pump 89.2 0 1 1049 0.9924457034938622 0.989642184557439 fluoroquinolone antibiotic antibiotic efflux 63 M0010194 1111525849484910_bin.15__k141_136913 AMMFCDDB_00003 1111525849484910_bin.15__k141_136913__AMMFCDDB_00003 1111525849484910_bin.15__k141_136913 C1656 AMMFCDDB_00003 ARO:3000804 MexF MexF is the multidrug inner membrane transporter of the MexEF-OprN complex. mexF corresponds to 2 loci in Pseudomonas aeruginosa PAO1 (gene name: mexF/mexB) and 4 loci in Pseudomonas aeruginosa LESB58 (gene name: mexD/mexB). resistance-nodulation-cell division (RND) antibiotic efflux pump 89.2 0 1 1049 0.9924457034938622 0.989642184557439 fluoroquinolone antibiotic antibiotic efflux 64 M0010195 1111525849484910_bin.15__k141_136913 AMMFCDDB_00003 1111525849484910_bin.15__k141_136913__AMMFCDDB_00003 1111525849484910_bin.15__k141_136913 C1656 AMMFCDDB_00003 ARO:3000804 MexF MexF is the multidrug inner membrane transporter of the MexEF-OprN complex. mexF corresponds to 2 loci in Pseudomonas aeruginosa PAO1 (gene name: mexF/mexB) and 4 loci in Pseudomonas aeruginosa LESB58 (gene name: mexD/mexB). resistance-nodulation-cell division (RND) antibiotic efflux pump 89.2 0 1 1049 0.9924457034938622 0.989642184557439 fluoroquinolone antibiotic antibiotic efflux 65 M0010196 1111525849484910_bin.15__k141_136913 AMMFCDDB_00003 1111525849484910_bin.15__k141_136913__AMMFCDDB_00003 1111525849484910_bin.15__k141_136913 C1656 AMMFCDDB_00003 ARO:3000804 MexF MexF is the multidrug inner membrane transporter of the MexEF-OprN complex. mexF corresponds to 2 loci in Pseudomonas aeruginosa PAO1 (gene name: mexF/mexB) and 4 loci in Pseudomonas aeruginosa LESB58 (gene name: mexD/mexB). resistance-nodulation-cell division (RND) antibiotic efflux pump 89.2 0 1 1049 0.9924457034938622 0.989642184557439 fluoroquinolone antibiotic antibiotic efflux 66 M0010205 1111525849484910_bin.15__k141_136913 AMMFCDDB_00003 1111525849484910_bin.15__k141_136913__AMMFCDDB_00003 1111525849484910_bin.15__k141_136913 C1656 AMMFCDDB_00003 ARO:3000804 MexF MexF is the multidrug inner membrane transporter of the MexEF-OprN complex. mexF corresponds to 2 loci in Pseudomonas aeruginosa PAO1 (gene name: mexF/mexB) and 4 loci in Pseudomonas aeruginosa LESB58 (gene name: mexD/mexB). resistance-nodulation-cell division (RND) antibiotic efflux pump 89.2 0 1 1049 0.9924457034938622 0.989642184557439 fluoroquinolone antibiotic antibiotic efflux 67 M0010206 1111525849484910_bin.15__k141_136913 AMMFCDDB_00003 1111525849484910_bin.15__k141_136913__AMMFCDDB_00003 1111525849484910_bin.15__k141_136913 C1656 AMMFCDDB_00003 ARO:3000804 MexF MexF is the multidrug inner membrane transporter of the MexEF-OprN complex. mexF corresponds to 2 loci in Pseudomonas aeruginosa PAO1 (gene name: mexF/mexB) and 4 loci in Pseudomonas aeruginosa LESB58 (gene name: mexD/mexB). resistance-nodulation-cell division (RND) antibiotic efflux pump 89.2 0 1 1049 0.9924457034938622 0.989642184557439 fluoroquinolone antibiotic antibiotic efflux 68 M0010210 1111525849484910_bin.15__k141_136913 AMMFCDDB_00003 1111525849484910_bin.15__k141_136913__AMMFCDDB_00003 1111525849484910_bin.15__k141_136913 C1656 AMMFCDDB_00003 ARO:3000804 MexF MexF is the multidrug inner membrane transporter of the MexEF-OprN complex. mexF corresponds to 2 loci in Pseudomonas aeruginosa PAO1 (gene name: mexF/mexB) and 4 loci in Pseudomonas aeruginosa LESB58 (gene name: mexD/mexB). resistance-nodulation-cell division (RND) antibiotic efflux pump 89.2 0 1 1049 0.9924457034938622 0.989642184557439 fluoroquinolone antibiotic antibiotic efflux 69 M0010212 1111525849484910_bin.15__k141_136913 AMMFCDDB_00002 1111525849484910_bin.15__k141_136913__AMMFCDDB_00002 1111525849484910_bin.15__k141_136913 C1656 AMMFCDDB_00002 ARO:3000803 MexE MexE is the membrane fusion protein of the MexEF-OprN multidrug efflux complex. resistance-nodulation-cell division (RND) antibiotic efflux pump 72 3.3e-189 9 413 0.9854721549636803 0.983091787439614 fluoroquinolone antibiotic antibiotic efflux 70 M0021601 1111525849736171_bin.24__k141_13581 PLGIHBHJ_00001 1111525849736171_bin.24__k141_13581__PLGIHBHJ_00001 1111525849736171_bin.24__k141_13581 C1967 PLGIHBHJ_00001 ARO:3007420 Klebsiella pneumoniae lamB with mutations conferring resistance to ceftazidime-avibactam LamB is a maltoporin that negatively regulates antibiotic resistance. Knockout strains of lamB are shown to exhibit higher levels of resistance than wild-type strains. Mutations in the lamB gene of Klebsiella are associated with resistance to ceftazidime-avibactam. Sugar Porin (SP) 77 2.07e-261 1 430 1.0116279069767442 1.01398601398601 fluoroquinolone antibiotic reduced permeability to antibiotic 71 M0021602 1111525849736171_bin.24__k141_13581 PLGIHBHJ_00001 1111525849736171_bin.24__k141_13581__PLGIHBHJ_00001 1111525849736171_bin.24__k141_13581 C1967 PLGIHBHJ_00001 ARO:3007420 Klebsiella pneumoniae lamB with mutations conferring resistance to ceftazidime-avibactam LamB is a maltoporin that negatively regulates antibiotic resistance. Knockout strains of lamB are shown to exhibit higher levels of resistance than wild-type strains. Mutations in the lamB gene of Klebsiella are associated with resistance to ceftazidime-avibactam. Sugar Porin (SP) 77 2.07e-261 1 430 1.0116279069767442 1.01398601398601 fluoroquinolone antibiotic reduced permeability to antibiotic 72 M0021603 1111525849736171_bin.24__k141_13581 PLGIHBHJ_00001 1111525849736171_bin.24__k141_13581__PLGIHBHJ_00001 1111525849736171_bin.24__k141_13581 C1967 PLGIHBHJ_00001 ARO:3007420 Klebsiella pneumoniae lamB with mutations conferring resistance to ceftazidime-avibactam LamB is a maltoporin that negatively regulates antibiotic resistance. Knockout strains of lamB are shown to exhibit higher levels of resistance than wild-type strains. Mutations in the lamB gene of Klebsiella are associated with resistance to ceftazidime-avibactam. Sugar Porin (SP) 77 2.07e-261 1 430 1.0116279069767442 1.01398601398601 fluoroquinolone antibiotic reduced permeability to antibiotic 73 M0021604 1111525849736171_bin.24__k141_13581 PLGIHBHJ_00001 1111525849736171_bin.24__k141_13581__PLGIHBHJ_00001 1111525849736171_bin.24__k141_13581 C1967 PLGIHBHJ_00001 ARO:3007420 Klebsiella pneumoniae lamB with mutations conferring resistance to ceftazidime-avibactam LamB is a maltoporin that negatively regulates antibiotic resistance. Knockout strains of lamB are shown to exhibit higher levels of resistance than wild-type strains. Mutations in the lamB gene of Klebsiella are associated with resistance to ceftazidime-avibactam. Sugar Porin (SP) 77 2.07e-261 1 430 1.0116279069767442 1.01398601398601 fluoroquinolone antibiotic reduced permeability to antibiotic 74 M0021605 1111525849736171_bin.24__k141_13581 PLGIHBHJ_00001 1111525849736171_bin.24__k141_13581__PLGIHBHJ_00001 1111525849736171_bin.24__k141_13581 C1967 PLGIHBHJ_00001 ARO:3007420 Klebsiella pneumoniae lamB with mutations conferring resistance to ceftazidime-avibactam LamB is a maltoporin that negatively regulates antibiotic resistance. Knockout strains of lamB are shown to exhibit higher levels of resistance than wild-type strains. Mutations in the lamB gene of Klebsiella are associated with resistance to ceftazidime-avibactam. Sugar Porin (SP) 77 2.07e-261 1 430 1.0116279069767442 1.01398601398601 fluoroquinolone antibiotic reduced permeability to antibiotic 75 M0021606 1111525849736171_bin.24__k141_13581 PLGIHBHJ_00001 1111525849736171_bin.24__k141_13581__PLGIHBHJ_00001 1111525849736171_bin.24__k141_13581 C1967 PLGIHBHJ_00001 ARO:3007420 Klebsiella pneumoniae lamB with mutations conferring resistance to ceftazidime-avibactam LamB is a maltoporin that negatively regulates antibiotic resistance. Knockout strains of lamB are shown to exhibit higher levels of resistance than wild-type strains. Mutations in the lamB gene of Klebsiella are associated with resistance to ceftazidime-avibactam. Sugar Porin (SP) 77 2.07e-261 1 430 1.0116279069767442 1.01398601398601 fluoroquinolone antibiotic reduced permeability to antibiotic 76 M0021607 1111525849736171_bin.24__k141_13581 PLGIHBHJ_00001 1111525849736171_bin.24__k141_13581__PLGIHBHJ_00001 1111525849736171_bin.24__k141_13581 C1967 PLGIHBHJ_00001 ARO:3007420 Klebsiella pneumoniae lamB with mutations conferring resistance to ceftazidime-avibactam LamB is a maltoporin that negatively regulates antibiotic resistance. Knockout strains of lamB are shown to exhibit higher levels of resistance than wild-type strains. Mutations in the lamB gene of Klebsiella are associated with resistance to ceftazidime-avibactam. Sugar Porin (SP) 77 2.07e-261 1 430 1.0116279069767442 1.01398601398601 fluoroquinolone antibiotic reduced permeability to antibiotic 77 M0021612 1111525849736171_bin.24__k141_282110 OFMJACGM_00005 1111525849736171_bin.24__k141_282110__OFMJACGM_00005 1111525849736171_bin.24__k141_282110 C1968 OFMJACGM_00005 ARO:3003922 oqxA RND efflux pump conferring resistance to fluoroquinolone. resistance-nodulation-cell division (RND) antibiotic efflux pump 72 3.3e-183 23 391 0.9618320610687023 0.966751918158568 fluoroquinolone antibiotic antibiotic efflux 78 M0021613 1111525849736171_bin.24__k141_282110 OFMJACGM_00005 1111525849736171_bin.24__k141_282110__OFMJACGM_00005 1111525849736171_bin.24__k141_282110 C1968 OFMJACGM_00005 ARO:3003922 oqxA RND efflux pump conferring resistance to fluoroquinolone. resistance-nodulation-cell division (RND) antibiotic efflux pump 72 3.3e-183 23 391 0.9618320610687023 0.966751918158568 fluoroquinolone antibiotic antibiotic efflux 79 M0022455 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 80 M0022456 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 81 M0022457 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 82 M0022458 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 83 M0022459 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 84 M0022460 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 85 M0022461 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 86 M0022462 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 87 M0022463 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 88 M0022464 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 89 M0022465 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 90 M0022473 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 91 M0022474 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 92 M0022475 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 93 M0022476 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 94 M0022477 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 95 M0022478 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 96 M0022479 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 97 M0022480 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 98 M0022481 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 99 M0022482 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 100 M0022483 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 101 M0022485 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 102 M0022486 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 103 M0022513 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 104 M0022514 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 105 M0022515 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 106 M0022516 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 107 M0022517 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 108 M0022518 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 109 M0022519 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 110 M0022532 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 111 M0022533 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 112 M0022534 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 113 M0022535 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 114 M0022536 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 115 M0022537 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 116 M0022538 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 117 M0022539 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 118 M0022540 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 119 M0022541 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 120 M0022542 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 121 M0022543 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 122 M0022544 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 123 M0022545 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 124 M0022546 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 125 M0022547 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 126 M0022554 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 127 M0022555 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 128 M0022556 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 129 M0022557 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 130 M0022558 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 131 M0022559 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 132 M0022560 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 133 M0022561 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 134 M0022566 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 135 M0022569 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 136 M0022571 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 137 M0022572 1111525849736979_bin.18__k141_31798 ALIGDCEL_00001 1111525849736979_bin.18__k141_31798__ALIGDCEL_00001 1111525849736979_bin.18__k141_31798 C2014 ALIGDCEL_00001 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.7 0 1 836 0.9870740305522914 0.990566037735849 pyrazine antibiotic antibiotic target alteration 138 M0029485 1111525849747079_bin.13__k141_113099 BLJGIOBO_00003 1111525849747079_bin.13__k141_113099__BLJGIOBO_00003 1111525849747079_bin.13__k141_113099 C2194 BLJGIOBO_00003 ARO:3004574 Acinetobacter baumannii AbaQ AbaQ is an MFS transporter mainly involved in the extrusion of quinolone-type drugs in A. baumannii. major facilitator superfamily (MFS) antibiotic efflux pump 72.4 7.21e-231 4 430 0.9727272727272728 0.986175115207373 fluoroquinolone antibiotic antibiotic efflux 139 M0035247 1111525849760419_bin.3__k141_39468 NLFLGJIB_00036 1111525849760419_bin.3__k141_39468__NLFLGJIB_00036 1111525849760419_bin.3__k141_39468 C2298 NLFLGJIB_00036 ARO:3000823 ramA RamA (resistance antibiotic multiple) is a positive regulator of AcrAB-TolC and leads to high level multidrug resistance in Klebsiella pneumoniae, Salmonella enterica, and Enterobacter aerugenes, increasing the expression of both the mar operon as well as AcrAB. RamA also decreases OmpF expression. resistance-nodulation-cell division (RND) antibiotic efflux pump 92 2.9e-77 1 113 1.0 0.911290322580645 fluoroquinolone antibiotic antibiotic efflux 140 M0056133 1111525849862289_bin.26__k141_590765 INMOJBGM_00002 1111525849862289_bin.26__k141_590765__INMOJBGM_00002 1111525849862289_bin.26__k141_590765 C2762 INMOJBGM_00002 ARO:3000250 ErmC ErmC is a methyltransferase that catalyzes the methylation of A2058 of the 23S ribosomal RNA in two steps. Expression of ErmC is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present, it binds the leader peptide causing a change in conformation allowing for the expression of ErmC. Erm 23S ribosomal RNA methyltransferase 99.6 9.79e-176 1 244 1.0 1 macrolide antibiotic antibiotic target alteration 141 M0056134 1111525849862289_bin.26__k141_590765 INMOJBGM_00002 1111525849862289_bin.26__k141_590765__INMOJBGM_00002 1111525849862289_bin.26__k141_590765 C2762 INMOJBGM_00002 ARO:3000250 ErmC ErmC is a methyltransferase that catalyzes the methylation of A2058 of the 23S ribosomal RNA in two steps. Expression of ErmC is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present, it binds the leader peptide causing a change in conformation allowing for the expression of ErmC. Erm 23S ribosomal RNA methyltransferase 99.6 9.79e-176 1 244 1.0 1 macrolide antibiotic antibiotic target alteration 142 M0056135 1111525849862289_bin.26__k141_590765 INMOJBGM_00002 1111525849862289_bin.26__k141_590765__INMOJBGM_00002 1111525849862289_bin.26__k141_590765 C2762 INMOJBGM_00002 ARO:3000250 ErmC ErmC is a methyltransferase that catalyzes the methylation of A2058 of the 23S ribosomal RNA in two steps. Expression of ErmC is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present, it binds the leader peptide causing a change in conformation allowing for the expression of ErmC. Erm 23S ribosomal RNA methyltransferase 99.6 9.79e-176 1 244 1.0 1 macrolide antibiotic antibiotic target alteration 143 M0056137 1111525849862289_bin.26__k141_590765 INMOJBGM_00002 1111525849862289_bin.26__k141_590765__INMOJBGM_00002 1111525849862289_bin.26__k141_590765 C2762 INMOJBGM_00002 ARO:3000250 ErmC ErmC is a methyltransferase that catalyzes the methylation of A2058 of the 23S ribosomal RNA in two steps. Expression of ErmC is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present, it binds the leader peptide causing a change in conformation allowing for the expression of ErmC. Erm 23S ribosomal RNA methyltransferase 99.6 9.79e-176 1 244 1.0 1 macrolide antibiotic antibiotic target alteration 144 M0056138 1111525849862289_bin.26__k141_590765 INMOJBGM_00002 1111525849862289_bin.26__k141_590765__INMOJBGM_00002 1111525849862289_bin.26__k141_590765 C2762 INMOJBGM_00002 ARO:3000250 ErmC ErmC is a methyltransferase that catalyzes the methylation of A2058 of the 23S ribosomal RNA in two steps. Expression of ErmC is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present, it binds the leader peptide causing a change in conformation allowing for the expression of ErmC. Erm 23S ribosomal RNA methyltransferase 99.6 9.79e-176 1 244 1.0 1 macrolide antibiotic antibiotic target alteration 145 M0056139 1111525849862289_bin.26__k141_590765 INMOJBGM_00002 1111525849862289_bin.26__k141_590765__INMOJBGM_00002 1111525849862289_bin.26__k141_590765 C2762 INMOJBGM_00002 ARO:3000250 ErmC ErmC is a methyltransferase that catalyzes the methylation of A2058 of the 23S ribosomal RNA in two steps. Expression of ErmC is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present, it binds the leader peptide causing a change in conformation allowing for the expression of ErmC. Erm 23S ribosomal RNA methyltransferase 99.6 9.79e-176 1 244 1.0 1 macrolide antibiotic antibiotic target alteration 146 M0059306 CP052009.1 LGLOEKLK_00039 CP052009.1__LGLOEKLK_00039 CP052009.1 C92 LGLOEKLK_00039 ARO:3000251 msrA MsrA is an ABC-F subfamily ribosomal protection protein expressed in Staphylococcus species which confers resistance to erythromycin and streptogramin B antibiotics through antibiotic target protection mechanisms. It is associated with plasmid DNA. msr-type ABC-F protein 95.7 2.0997789948253e-320 1 488 1.0 1 macrolide antibiotic antibiotic target protection 147 M0059307 CP052009.1 LGLOEKLK_00039 CP052009.1__LGLOEKLK_00039 CP052009.1 C92 LGLOEKLK_00039 ARO:3000251 msrA MsrA is an ABC-F subfamily ribosomal protection protein expressed in Staphylococcus species which confers resistance to erythromycin and streptogramin B antibiotics through antibiotic target protection mechanisms. It is associated with plasmid DNA. msr-type ABC-F protein 95.7 2.0997789948253e-320 1 488 1.0 1 macrolide antibiotic antibiotic target protection 148 M0059308 CP052009.1 LGLOEKLK_00039 CP052009.1__LGLOEKLK_00039 CP052009.1 C92 LGLOEKLK_00039 ARO:3000251 msrA MsrA is an ABC-F subfamily ribosomal protection protein expressed in Staphylococcus species which confers resistance to erythromycin and streptogramin B antibiotics through antibiotic target protection mechanisms. It is associated with plasmid DNA. msr-type ABC-F protein 95.7 2.0997789948253e-320 1 488 1.0 1 macrolide antibiotic antibiotic target protection 149 M0059309 CP052009.1 LGLOEKLK_00039 CP052009.1__LGLOEKLK_00039 CP052009.1 C92 LGLOEKLK_00039 ARO:3000251 msrA MsrA is an ABC-F subfamily ribosomal protection protein expressed in Staphylococcus species which confers resistance to erythromycin and streptogramin B antibiotics through antibiotic target protection mechanisms. It is associated with plasmid DNA. msr-type ABC-F protein 95.7 2.0997789948253e-320 1 488 1.0 1 macrolide antibiotic antibiotic target protection 150 M0059310 CP052009.1 LGLOEKLK_00038 CP052009.1__LGLOEKLK_00038 CP052009.1 C92 LGLOEKLK_00038 ARO:3000319 mphC The mphC gene was identified from Staphylococcus aureus. This gene shows similarity to mphB gene from Escherchia coli. macrolide phosphotransferase (MPH) 98.7 1.82e-228 1 299 1.0 1 macrolide antibiotic antibiotic inactivation 151 M0059329 CP052009.1 LGLOEKLK_00039 CP052009.1__LGLOEKLK_00039 CP052009.1 C92 LGLOEKLK_00039 ARO:3000251 msrA MsrA is an ABC-F subfamily ribosomal protection protein expressed in Staphylococcus species which confers resistance to erythromycin and streptogramin B antibiotics through antibiotic target protection mechanisms. It is associated with plasmid DNA. msr-type ABC-F protein 95.7 2.0997789948253e-320 1 488 1.0 1 macrolide antibiotic antibiotic target protection 152 M0059333 CP052009.1 LGLOEKLK_00039 CP052009.1__LGLOEKLK_00039 CP052009.1 C92 LGLOEKLK_00039 ARO:3000251 msrA MsrA is an ABC-F subfamily ribosomal protection protein expressed in Staphylococcus species which confers resistance to erythromycin and streptogramin B antibiotics through antibiotic target protection mechanisms. It is associated with plasmid DNA. msr-type ABC-F protein 95.7 2.0997789948253e-320 1 488 1.0 1 macrolide antibiotic antibiotic target protection 153 M0059334 CP052009.1 LGLOEKLK_00039 CP052009.1__LGLOEKLK_00039 CP052009.1 C92 LGLOEKLK_00039 ARO:3000251 msrA MsrA is an ABC-F subfamily ribosomal protection protein expressed in Staphylococcus species which confers resistance to erythromycin and streptogramin B antibiotics through antibiotic target protection mechanisms. It is associated with plasmid DNA. msr-type ABC-F protein 95.7 2.0997789948253e-320 1 488 1.0 1 macrolide antibiotic antibiotic target protection 154 M0059335 CP052009.1 LGLOEKLK_00039 CP052009.1__LGLOEKLK_00039 CP052009.1 C92 LGLOEKLK_00039 ARO:3000251 msrA MsrA is an ABC-F subfamily ribosomal protection protein expressed in Staphylococcus species which confers resistance to erythromycin and streptogramin B antibiotics through antibiotic target protection mechanisms. It is associated with plasmid DNA. msr-type ABC-F protein 95.7 2.0997789948253e-320 1 488 1.0 1 macrolide antibiotic antibiotic target protection 155 M0059665 CP113227.1 GAHJGFOD_00167 CP113227.1__GAHJGFOD_00167 CP113227.1 C206 GAHJGFOD_00167 ARO:3002272 VIM-2 VIM-2 is a beta-lactamase found in Pseudomonas spp. VIM beta-lactamase 100 1.91e-193 1 266 1.0 1 carbapenem antibiotic inactivation 156 M0059666 CP113227.1 GAHJGFOD_00167 CP113227.1__GAHJGFOD_00167 CP113227.1 C206 GAHJGFOD_00167 ARO:3002272 VIM-2 VIM-2 is a beta-lactamase found in Pseudomonas spp. VIM beta-lactamase 100 1.91e-193 1 266 1.0 1 carbapenem antibiotic inactivation 157 M0059667 CP113227.1 GAHJGFOD_00167 CP113227.1__GAHJGFOD_00167 CP113227.1 C206 GAHJGFOD_00167 ARO:3002272 VIM-2 VIM-2 is a beta-lactamase found in Pseudomonas spp. VIM beta-lactamase 100 1.91e-193 1 266 1.0 1 carbapenem antibiotic inactivation 158 M0059668 CP113227.1 GAHJGFOD_00167 CP113227.1__GAHJGFOD_00167 CP113227.1 C206 GAHJGFOD_00167 ARO:3002272 VIM-2 VIM-2 is a beta-lactamase found in Pseudomonas spp. VIM beta-lactamase 100 1.91e-193 1 266 1.0 1 carbapenem antibiotic inactivation 159 M0059689 CP113227.1 GAHJGFOD_00169 CP113227.1__GAHJGFOD_00169 CP113227.1 C206 GAHJGFOD_00169 ARO:3002864 dfrB1 A plasmid-associated trimethoprim-resistant dihydrofolate reductase detected in Bordetella bronchispetica on pKBB958. trimethoprim resistant dihydrofolate reductase dfr 98.7 1.44e-54 1 78 1.0 1 diaminopyrimidine antibiotic antibiotic target replacement 160 M0059690 CP113227.1 GAHJGFOD_00169 CP113227.1__GAHJGFOD_00169 CP113227.1 C206 GAHJGFOD_00169 ARO:3002864 dfrB1 A plasmid-associated trimethoprim-resistant dihydrofolate reductase detected in Bordetella bronchispetica on pKBB958. trimethoprim resistant dihydrofolate reductase dfr 98.7 1.44e-54 1 78 1.0 1 diaminopyrimidine antibiotic antibiotic target replacement 161 M0064519 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 162 M0064520 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 163 M0064521 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 164 M0064522 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 165 M0064523 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 166 M0064524 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 167 M0064525 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 168 M0064526 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 169 M0064527 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 170 M0064528 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 171 M0064529 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 172 M0064530 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 173 M0064531 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 174 M0064532 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 175 M0064533 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 176 M0064534 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 177 M0064535 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 178 M0064536 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 179 M0064537 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 180 M0064538 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 181 M0064539 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 182 M0064540 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 183 M0064541 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 184 M0064542 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 185 M0064543 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 186 M0064544 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 187 M0064545 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 188 M0064546 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 189 M0064547 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 190 M0064548 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 191 M0064549 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 192 M0064550 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 193 M0064551 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 194 M0064552 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 195 M0064553 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 196 M0064554 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 197 M0064555 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 198 M0064556 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 199 M0064557 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 200 M0064558 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 201 M0064559 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 202 M0064560 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 203 M0064561 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 204 M0064562 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 205 M0064563 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 206 M0064564 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 207 M0064565 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 208 M0064566 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 209 M0064567 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 210 M0064568 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 211 M0064569 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 212 M0064570 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 213 M0064571 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 214 M0064572 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 215 M0064573 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 216 M0064579 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 217 M0064580 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 218 M0064581 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 219 M0064582 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 220 M0064583 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 221 M0064584 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 222 M0064789 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 223 M0064790 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 224 M0064791 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 225 M0064798 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 226 M0064803 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 227 M0064804 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 228 M0064805 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 229 M0064806 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 230 M0064807 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 231 M0064811 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201__DPMGKMCC_00009 DP1807004505_bin.10__NODE_127_length_11143_cov_5.836201 C2866 DPMGKMCC_00009 ARO:3004957 Mycobacterium tuberculosis clpC1 with mutation conferring resistance to pyrazinamide Mutations that occur in clpC1 that result in or contribute to antibiotic resistance to pyrazinamide. pyrazinamide resistant clpC1 73.3 0 1 820 0.985781990521327 0.981132075471698 pyrazine antibiotic antibiotic target alteration 232 M0069114 DSKIN0031-1_bin.8__k141_19928 COFOKFAB_00016 DSKIN0031-1_bin.8__k141_19928__COFOKFAB_00016 DSKIN0031-1_bin.8__k141_19928 C2988 COFOKFAB_00016 ARO:3003010 ceoB ceoB is a cytoplasmic membrane component of the CeoAB-OpcM efflux pump. resistance-nodulation-cell division (RND) antibiotic efflux pump 71.6 0 1 1026 0.9473684210526315 0.999026290165531 fluoroquinolone antibiotic antibiotic efflux 233 M0069115 DSKIN0031-1_bin.8__k141_19928 COFOKFAB_00016 DSKIN0031-1_bin.8__k141_19928__COFOKFAB_00016 DSKIN0031-1_bin.8__k141_19928 C2988 COFOKFAB_00016 ARO:3003010 ceoB ceoB is a cytoplasmic membrane component of the CeoAB-OpcM efflux pump. resistance-nodulation-cell division (RND) antibiotic efflux pump 71.6 0 1 1026 0.9473684210526315 0.999026290165531 fluoroquinolone antibiotic antibiotic efflux 234 M0069116 DSKIN0031-1_bin.8__k141_19928 COFOKFAB_00016 DSKIN0031-1_bin.8__k141_19928__COFOKFAB_00016 DSKIN0031-1_bin.8__k141_19928 C2988 COFOKFAB_00016 ARO:3003010 ceoB ceoB is a cytoplasmic membrane component of the CeoAB-OpcM efflux pump. resistance-nodulation-cell division (RND) antibiotic efflux pump 71.6 0 1 1026 0.9473684210526315 0.999026290165531 fluoroquinolone antibiotic antibiotic efflux 235 M0069117 DSKIN0031-1_bin.8__k141_19928 COFOKFAB_00016 DSKIN0031-1_bin.8__k141_19928__COFOKFAB_00016 DSKIN0031-1_bin.8__k141_19928 C2988 COFOKFAB_00016 ARO:3003010 ceoB ceoB is a cytoplasmic membrane component of the CeoAB-OpcM efflux pump. resistance-nodulation-cell division (RND) antibiotic efflux pump 71.6 0 1 1026 0.9473684210526315 0.999026290165531 fluoroquinolone antibiotic antibiotic efflux 236 M0069118 DSKIN0031-1_bin.8__k141_19928 COFOKFAB_00016 DSKIN0031-1_bin.8__k141_19928__COFOKFAB_00016 DSKIN0031-1_bin.8__k141_19928 C2988 COFOKFAB_00016 ARO:3003010 ceoB ceoB is a cytoplasmic membrane component of the CeoAB-OpcM efflux pump. resistance-nodulation-cell division (RND) antibiotic efflux pump 71.6 0 1 1026 0.9473684210526315 0.999026290165531 fluoroquinolone antibiotic antibiotic efflux 237 M0069119 DSKIN0031-1_bin.8__k141_19928 COFOKFAB_00016 DSKIN0031-1_bin.8__k141_19928__COFOKFAB_00016 DSKIN0031-1_bin.8__k141_19928 C2988 COFOKFAB_00016 ARO:3003010 ceoB ceoB is a cytoplasmic membrane component of the CeoAB-OpcM efflux pump. resistance-nodulation-cell division (RND) antibiotic efflux pump 71.6 0 1 1026 0.9473684210526315 0.999026290165531 fluoroquinolone antibiotic antibiotic efflux 238 M0069120 DSKIN0031-1_bin.8__k141_19928 COFOKFAB_00016 DSKIN0031-1_bin.8__k141_19928__COFOKFAB_00016 DSKIN0031-1_bin.8__k141_19928 C2988 COFOKFAB_00016 ARO:3003010 ceoB ceoB is a cytoplasmic membrane component of the CeoAB-OpcM efflux pump. resistance-nodulation-cell division (RND) antibiotic efflux pump 71.6 0 1 1026 0.9473684210526315 0.999026290165531 fluoroquinolone antibiotic antibiotic efflux 239 M0071129 KR827394.1 BKPKMKFO_00166 KR827394.1__BKPKMKFO_00166 KR827394.1 C238 BKPKMKFO_00166 ARO:3000504 golS GolS is a regulator activated by the presence of golD, and promotes the expression of the MdsABC efflux pump. resistance-nodulation-cell division (RND) antibiotic efflux pump 79.5 3.69e-78 1 146 0.9182389937106918 0.948051948051948 monobactam antibiotic efflux 240 M0071171 LR735438.1 PCIDKJBF_00045 LR735438.1__PCIDKJBF_00045 LR735438.1 C244 PCIDKJBF_00045 ARO:3003046 qacA qacA is a subunit of the qac multidrug efflux pump. major facilitator superfamily (MFS) antibiotic efflux pump 98.8 0 1 514 1.0 1 fluoroquinolone antibiotic antibiotic efflux 241 M0074272 MET0114_bin.4__k81_1205 OAHCGHHK_00002 MET0114_bin.4__k81_1205__OAHCGHHK_00002 MET0114_bin.4__k81_1205 C3092 OAHCGHHK_00002 ARO:3000565 tet(38) Tet38 is a tetracycline efflux pump found in the Gram-positive Staphylococcus aureus. It is regulated by mgrA, which also regulates NorB. major facilitator superfamily (MFS) antibiotic efflux pump 99.8 5.24e-298 3 452 0.995575221238938 1 tetracycline antibiotic antibiotic efflux 242 M0074273 MET0114_bin.4__k81_1205 OAHCGHHK_00002 MET0114_bin.4__k81_1205__OAHCGHHK_00002 MET0114_bin.4__k81_1205 C3092 OAHCGHHK_00002 ARO:3000565 tet(38) Tet38 is a tetracycline efflux pump found in the Gram-positive Staphylococcus aureus. It is regulated by mgrA, which also regulates NorB. major facilitator superfamily (MFS) antibiotic efflux pump 99.8 5.24e-298 3 452 0.995575221238938 1 tetracycline antibiotic antibiotic efflux 243 M0074274 MET0114_bin.4__k81_1205 OAHCGHHK_00002 MET0114_bin.4__k81_1205__OAHCGHHK_00002 MET0114_bin.4__k81_1205 C3092 OAHCGHHK_00002 ARO:3000565 tet(38) Tet38 is a tetracycline efflux pump found in the Gram-positive Staphylococcus aureus. It is regulated by mgrA, which also regulates NorB. major facilitator superfamily (MFS) antibiotic efflux pump 99.8 5.24e-298 3 452 0.995575221238938 1 tetracycline antibiotic antibiotic efflux 244 M0074275 MET0114_bin.4__k81_1205 OAHCGHHK_00002 MET0114_bin.4__k81_1205__OAHCGHHK_00002 MET0114_bin.4__k81_1205 C3092 OAHCGHHK_00002 ARO:3000565 tet(38) Tet38 is a tetracycline efflux pump found in the Gram-positive Staphylococcus aureus. It is regulated by mgrA, which also regulates NorB. major facilitator superfamily (MFS) antibiotic efflux pump 99.8 5.24e-298 3 452 0.995575221238938 1 tetracycline antibiotic antibiotic efflux 245 M0074276 MET0114_bin.4__k81_1205 OAHCGHHK_00002 MET0114_bin.4__k81_1205__OAHCGHHK_00002 MET0114_bin.4__k81_1205 C3092 OAHCGHHK_00002 ARO:3000565 tet(38) Tet38 is a tetracycline efflux pump found in the Gram-positive Staphylococcus aureus. It is regulated by mgrA, which also regulates NorB. major facilitator superfamily (MFS) antibiotic efflux pump 99.8 5.24e-298 3 452 0.995575221238938 1 tetracycline antibiotic antibiotic efflux 246 M0074292 MET0114_bin.4__k81_1205 OAHCGHHK_00002 MET0114_bin.4__k81_1205__OAHCGHHK_00002 MET0114_bin.4__k81_1205 C3092 OAHCGHHK_00002 ARO:3000565 tet(38) Tet38 is a tetracycline efflux pump found in the Gram-positive Staphylococcus aureus. It is regulated by mgrA, which also regulates NorB. major facilitator superfamily (MFS) antibiotic efflux pump 99.8 5.24e-298 3 452 0.995575221238938 1 tetracycline antibiotic antibiotic efflux 247 M0074293 MET0114_bin.4__k81_1205 OAHCGHHK_00002 MET0114_bin.4__k81_1205__OAHCGHHK_00002 MET0114_bin.4__k81_1205 C3092 OAHCGHHK_00002 ARO:3000565 tet(38) Tet38 is a tetracycline efflux pump found in the Gram-positive Staphylococcus aureus. It is regulated by mgrA, which also regulates NorB. major facilitator superfamily (MFS) antibiotic efflux pump 99.8 5.24e-298 3 452 0.995575221238938 1 tetracycline antibiotic antibiotic efflux 248 M0074294 MET0114_bin.4__k81_1205 OAHCGHHK_00002 MET0114_bin.4__k81_1205__OAHCGHHK_00002 MET0114_bin.4__k81_1205 C3092 OAHCGHHK_00002 ARO:3000565 tet(38) Tet38 is a tetracycline efflux pump found in the Gram-positive Staphylococcus aureus. It is regulated by mgrA, which also regulates NorB. major facilitator superfamily (MFS) antibiotic efflux pump 99.8 5.24e-298 3 452 0.995575221238938 1 tetracycline antibiotic antibiotic efflux 249 M0075201 MET0158_bin.3__k81_10926 LFCOFDKL_00022 MET0158_bin.3__k81_10926__LFCOFDKL_00022 MET0158_bin.3__k81_10926 C3099 LFCOFDKL_00022 ARO:3007843 VRA-F VRA-F is an ABC transporter ATP-binding protein, or ATP-binding cassette. ATP-binding cassette (ABC) antibiotic efflux pump 72.6 2.43e-131 23 274 0.9163636363636364 0.99604743083004 glycopeptide antibiotic antibiotic efflux 250 M0075202 MET0158_bin.3__k81_10926 LFCOFDKL_00022 MET0158_bin.3__k81_10926__LFCOFDKL_00022 MET0158_bin.3__k81_10926 C3099 LFCOFDKL_00022 ARO:3007843 VRA-F VRA-F is an ABC transporter ATP-binding protein, or ATP-binding cassette. ATP-binding cassette (ABC) antibiotic efflux pump 72.6 2.43e-131 23 274 0.9163636363636364 0.99604743083004 glycopeptide antibiotic antibiotic efflux 251 M0076322 MET0225_bin.9__k81_94919 CLDLBHMF_00002 MET0225_bin.9__k81_94919__CLDLBHMF_00002 MET0225_bin.9__k81_94919 C3133 CLDLBHMF_00002 ARO:3004721 Mycobacterium tuberculosis rpsA mutations conferring resistance to pyrazinamide RpsA, the 30S ribosomal protein S1 of Mycobacterium tuberculosis, is involved in trans-translation and is targeted by pyrazinonic acid, the active form of the antibiotic pyrazinamide, which disrupts the initiation of mRNA translation. Mutations in the amino acid sequence of rpsA can confer resistance to pyrazinamide maintaining rpsA function. pyrazinamide resistant rpsA 76.4 1.03e-240 28 498 0.9538152610441767 0.987525987525988 pyrazine antibiotic antibiotic target alteration 252 M0076323 MET0225_bin.9__k81_94919 CLDLBHMF_00002 MET0225_bin.9__k81_94919__CLDLBHMF_00002 MET0225_bin.9__k81_94919 C3133 CLDLBHMF_00002 ARO:3004721 Mycobacterium tuberculosis rpsA mutations conferring resistance to pyrazinamide RpsA, the 30S ribosomal protein S1 of Mycobacterium tuberculosis, is involved in trans-translation and is targeted by pyrazinonic acid, the active form of the antibiotic pyrazinamide, which disrupts the initiation of mRNA translation. Mutations in the amino acid sequence of rpsA can confer resistance to pyrazinamide maintaining rpsA function. pyrazinamide resistant rpsA 76.4 1.03e-240 28 498 0.9538152610441767 0.987525987525988 pyrazine antibiotic antibiotic target alteration 253 M0080845 MET0490_bin.4__k81_25948 ABFKLGAC_00038 MET0490_bin.4__k81_25948__ABFKLGAC_00038 MET0490_bin.4__k81_25948 C3229 ABFKLGAC_00038 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 82.1 1.37e-274 1 458 0.9978213507625272 0.997821350762527 phosphonic acid antibiotic antibiotic target alteration 254 M0084526 NC_005000.1 INKOPDBK_00021 NC_005000.1__INKOPDBK_00021 NC_005000.1 C277 INKOPDBK_00021 ARO:3000375 ErmB ErmB confers the MLSb phenotype. Similar to ErmC, expression of ErmB is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present, it binds the leader peptide causing a change in conformation allowing for the expression of ErmB. Erm 23S ribosomal RNA methyltransferase 98.4 1.13e-173 1 245 1.0 0.987903225806452 macrolide antibiotic antibiotic target alteration 255 M0084527 NC_005000.1 INKOPDBK_00021 NC_005000.1__INKOPDBK_00021 NC_005000.1 C277 INKOPDBK_00021 ARO:3000375 ErmB ErmB confers the MLSb phenotype. Similar to ErmC, expression of ErmB is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present, it binds the leader peptide causing a change in conformation allowing for the expression of ErmB. Erm 23S ribosomal RNA methyltransferase 98.4 1.13e-173 1 245 1.0 0.987903225806452 macrolide antibiotic antibiotic target alteration 256 M0084528 NC_005000.1 INKOPDBK_00014 NC_005000.1__INKOPDBK_00014 NC_005000.1 C277 INKOPDBK_00014 ARO:3002897 SAT-4 SAT-4 is a plasmid-mediated streptothricin acetyltransferase and streptothricin (a nucleoside antibiotic) resistant determinant. Originally described from a Campylobacter coli BE/G4 plasmid gene sequence by Jacob et al, 1994. streptothricin acetyltransferase (SAT) 99.4 1.34e-130 1 180 1.0 1 nucleoside antibiotic antibiotic inactivation 257 M0084529 NC_005000.1 INKOPDBK_00014 NC_005000.1__INKOPDBK_00014 NC_005000.1 C277 INKOPDBK_00014 ARO:3002897 SAT-4 SAT-4 is a plasmid-mediated streptothricin acetyltransferase and streptothricin (a nucleoside antibiotic) resistant determinant. Originally described from a Campylobacter coli BE/G4 plasmid gene sequence by Jacob et al, 1994. streptothricin acetyltransferase (SAT) 99.4 1.34e-130 1 180 1.0 1 nucleoside antibiotic antibiotic inactivation 258 M0084530 NC_005000.1 INKOPDBK_00014 NC_005000.1__INKOPDBK_00014 NC_005000.1 C277 INKOPDBK_00014 ARO:3002897 SAT-4 SAT-4 is a plasmid-mediated streptothricin acetyltransferase and streptothricin (a nucleoside antibiotic) resistant determinant. Originally described from a Campylobacter coli BE/G4 plasmid gene sequence by Jacob et al, 1994. streptothricin acetyltransferase (SAT) 99.4 1.34e-130 1 180 1.0 1 nucleoside antibiotic antibiotic inactivation 259 M0084633 NC_013382.1 CGPOLLLN_00001 NC_013382.1__CGPOLLLN_00001 NC_013382.1 C4 CGPOLLLN_00001 ARO:3003046 qacA qacA is a subunit of the qac multidrug efflux pump. major facilitator superfamily (MFS) antibiotic efflux pump 99.8 0 1 514 1.0 1 fluoroquinolone antibiotic antibiotic efflux 260 M0084634 NC_013382.1 CGPOLLLN_00001 NC_013382.1__CGPOLLLN_00001 NC_013382.1 C4 CGPOLLLN_00001 ARO:3003046 qacA qacA is a subunit of the qac multidrug efflux pump. major facilitator superfamily (MFS) antibiotic efflux pump 99.8 0 1 514 1.0 1 fluoroquinolone antibiotic antibiotic efflux 261 M0084669 NC_015423.1 EHFCPMHH_00071 NC_015423.1__EHFCPMHH_00071 NC_015423.1 C320 EHFCPMHH_00071 ARO:3003923 oqxB RND efflux pump conferring resistance to fluoroquinolone. resistance-nodulation-cell division (RND) antibiotic efflux pump 72.5 0 1 1041 0.9867298578199052 0.991428571428571 fluoroquinolone antibiotic antibiotic efflux 262 M0084670 NC_015423.1 EHFCPMHH_00071 NC_015423.1__EHFCPMHH_00071 NC_015423.1 C320 EHFCPMHH_00071 ARO:3003923 oqxB RND efflux pump conferring resistance to fluoroquinolone. resistance-nodulation-cell division (RND) antibiotic efflux pump 72.5 0 1 1041 0.9867298578199052 0.991428571428571 fluoroquinolone antibiotic antibiotic efflux 263 M0084671 NC_015423.1 EHFCPMHH_00071 NC_015423.1__EHFCPMHH_00071 NC_015423.1 C320 EHFCPMHH_00071 ARO:3003923 oqxB RND efflux pump conferring resistance to fluoroquinolone. resistance-nodulation-cell division (RND) antibiotic efflux pump 72.5 0 1 1041 0.9867298578199052 0.991428571428571 fluoroquinolone antibiotic antibiotic efflux 264 M0086875 NZ_AP023307.1 JFGLBHGK_00006 NZ_AP023307.1__JFGLBHGK_00006 NZ_AP023307.1 C371 JFGLBHGK_00006 ARO:3000186 tet(M) Tet(M) is a ribosomal protection protein that confers tetracycline resistance. It is found on transposable DNA elements and its horizontal transfer between bacterial species has been documented. tetracycline-resistant ribosomal protection protein 96.1 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 265 M0086876 NZ_AP023307.1 JFGLBHGK_00006 NZ_AP023307.1__JFGLBHGK_00006 NZ_AP023307.1 C371 JFGLBHGK_00006 ARO:3000186 tet(M) Tet(M) is a ribosomal protection protein that confers tetracycline resistance. It is found on transposable DNA elements and its horizontal transfer between bacterial species has been documented. tetracycline-resistant ribosomal protection protein 96.1 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 266 M0086877 NZ_AP023307.1 JFGLBHGK_00006 NZ_AP023307.1__JFGLBHGK_00006 NZ_AP023307.1 C371 JFGLBHGK_00006 ARO:3000186 tet(M) Tet(M) is a ribosomal protection protein that confers tetracycline resistance. It is found on transposable DNA elements and its horizontal transfer between bacterial species has been documented. tetracycline-resistant ribosomal protection protein 96.1 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 267 M0086878 NZ_AP023307.1 JFGLBHGK_00006 NZ_AP023307.1__JFGLBHGK_00006 NZ_AP023307.1 C371 JFGLBHGK_00006 ARO:3000186 tet(M) Tet(M) is a ribosomal protection protein that confers tetracycline resistance. It is found on transposable DNA elements and its horizontal transfer between bacterial species has been documented. tetracycline-resistant ribosomal protection protein 96.1 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 268 M0086879 NZ_AP023307.1 JFGLBHGK_00006 NZ_AP023307.1__JFGLBHGK_00006 NZ_AP023307.1 C371 JFGLBHGK_00006 ARO:3000186 tet(M) Tet(M) is a ribosomal protection protein that confers tetracycline resistance. It is found on transposable DNA elements and its horizontal transfer between bacterial species has been documented. tetracycline-resistant ribosomal protection protein 96.1 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 269 M0086880 NZ_AP023307.1 JFGLBHGK_00006 NZ_AP023307.1__JFGLBHGK_00006 NZ_AP023307.1 C371 JFGLBHGK_00006 ARO:3000186 tet(M) Tet(M) is a ribosomal protection protein that confers tetracycline resistance. It is found on transposable DNA elements and its horizontal transfer between bacterial species has been documented. tetracycline-resistant ribosomal protection protein 96.1 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 270 M0086881 NZ_AP023307.1 JFGLBHGK_00006 NZ_AP023307.1__JFGLBHGK_00006 NZ_AP023307.1 C371 JFGLBHGK_00006 ARO:3000186 tet(M) Tet(M) is a ribosomal protection protein that confers tetracycline resistance. It is found on transposable DNA elements and its horizontal transfer between bacterial species has been documented. tetracycline-resistant ribosomal protection protein 96.1 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 271 M0086882 NZ_AP023307.1 JFGLBHGK_00006 NZ_AP023307.1__JFGLBHGK_00006 NZ_AP023307.1 C371 JFGLBHGK_00006 ARO:3000186 tet(M) Tet(M) is a ribosomal protection protein that confers tetracycline resistance. It is found on transposable DNA elements and its horizontal transfer between bacterial species has been documented. tetracycline-resistant ribosomal protection protein 96.1 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 272 M0086883 NZ_AP023307.1 JFGLBHGK_00006 NZ_AP023307.1__JFGLBHGK_00006 NZ_AP023307.1 C371 JFGLBHGK_00006 ARO:3000186 tet(M) Tet(M) is a ribosomal protection protein that confers tetracycline resistance. It is found on transposable DNA elements and its horizontal transfer between bacterial species has been documented. tetracycline-resistant ribosomal protection protein 96.1 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 273 M0086884 NZ_AP023307.1 JFGLBHGK_00006 NZ_AP023307.1__JFGLBHGK_00006 NZ_AP023307.1 C371 JFGLBHGK_00006 ARO:3000186 tet(M) Tet(M) is a ribosomal protection protein that confers tetracycline resistance. It is found on transposable DNA elements and its horizontal transfer between bacterial species has been documented. tetracycline-resistant ribosomal protection protein 96.1 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 274 M0086885 NZ_AP023307.1 JFGLBHGK_00006 NZ_AP023307.1__JFGLBHGK_00006 NZ_AP023307.1 C371 JFGLBHGK_00006 ARO:3000186 tet(M) Tet(M) is a ribosomal protection protein that confers tetracycline resistance. It is found on transposable DNA elements and its horizontal transfer between bacterial species has been documented. tetracycline-resistant ribosomal protection protein 96.1 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 275 M0086886 NZ_AP023307.1 JFGLBHGK_00006 NZ_AP023307.1__JFGLBHGK_00006 NZ_AP023307.1 C371 JFGLBHGK_00006 ARO:3000186 tet(M) Tet(M) is a ribosomal protection protein that confers tetracycline resistance. It is found on transposable DNA elements and its horizontal transfer between bacterial species has been documented. tetracycline-resistant ribosomal protection protein 96.1 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 276 M0086887 NZ_AP023307.1 JFGLBHGK_00006 NZ_AP023307.1__JFGLBHGK_00006 NZ_AP023307.1 C371 JFGLBHGK_00006 ARO:3000186 tet(M) Tet(M) is a ribosomal protection protein that confers tetracycline resistance. It is found on transposable DNA elements and its horizontal transfer between bacterial species has been documented. tetracycline-resistant ribosomal protection protein 96.1 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 277 M0086888 NZ_AP023307.1 JFGLBHGK_00006 NZ_AP023307.1__JFGLBHGK_00006 NZ_AP023307.1 C371 JFGLBHGK_00006 ARO:3000186 tet(M) Tet(M) is a ribosomal protection protein that confers tetracycline resistance. It is found on transposable DNA elements and its horizontal transfer between bacterial species has been documented. tetracycline-resistant ribosomal protection protein 96.1 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 278 M0086889 NZ_AP023307.1 JFGLBHGK_00006 NZ_AP023307.1__JFGLBHGK_00006 NZ_AP023307.1 C371 JFGLBHGK_00006 ARO:3000186 tet(M) Tet(M) is a ribosomal protection protein that confers tetracycline resistance. It is found on transposable DNA elements and its horizontal transfer between bacterial species has been documented. tetracycline-resistant ribosomal protection protein 96.1 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 279 M0086890 NZ_AP023307.1 JFGLBHGK_00006 NZ_AP023307.1__JFGLBHGK_00006 NZ_AP023307.1 C371 JFGLBHGK_00006 ARO:3000186 tet(M) Tet(M) is a ribosomal protection protein that confers tetracycline resistance. It is found on transposable DNA elements and its horizontal transfer between bacterial species has been documented. tetracycline-resistant ribosomal protection protein 96.1 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 280 M0086891 NZ_AP023307.1 JFGLBHGK_00006 NZ_AP023307.1__JFGLBHGK_00006 NZ_AP023307.1 C371 JFGLBHGK_00006 ARO:3000186 tet(M) Tet(M) is a ribosomal protection protein that confers tetracycline resistance. It is found on transposable DNA elements and its horizontal transfer between bacterial species has been documented. tetracycline-resistant ribosomal protection protein 96.1 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 281 M0086892 NZ_AP023307.1 JFGLBHGK_00006 NZ_AP023307.1__JFGLBHGK_00006 NZ_AP023307.1 C371 JFGLBHGK_00006 ARO:3000186 tet(M) Tet(M) is a ribosomal protection protein that confers tetracycline resistance. It is found on transposable DNA elements and its horizontal transfer between bacterial species has been documented. tetracycline-resistant ribosomal protection protein 96.1 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 282 M0086893 NZ_AP023307.1 JFGLBHGK_00006 NZ_AP023307.1__JFGLBHGK_00006 NZ_AP023307.1 C371 JFGLBHGK_00006 ARO:3000186 tet(M) Tet(M) is a ribosomal protection protein that confers tetracycline resistance. It is found on transposable DNA elements and its horizontal transfer between bacterial species has been documented. tetracycline-resistant ribosomal protection protein 96.1 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 283 M0086894 NZ_AP023307.1 JFGLBHGK_00006 NZ_AP023307.1__JFGLBHGK_00006 NZ_AP023307.1 C371 JFGLBHGK_00006 ARO:3000186 tet(M) Tet(M) is a ribosomal protection protein that confers tetracycline resistance. It is found on transposable DNA elements and its horizontal transfer between bacterial species has been documented. tetracycline-resistant ribosomal protection protein 96.1 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 284 M0086895 NZ_AP023307.1 JFGLBHGK_00006 NZ_AP023307.1__JFGLBHGK_00006 NZ_AP023307.1 C371 JFGLBHGK_00006 ARO:3000186 tet(M) Tet(M) is a ribosomal protection protein that confers tetracycline resistance. It is found on transposable DNA elements and its horizontal transfer between bacterial species has been documented. tetracycline-resistant ribosomal protection protein 96.1 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 285 M0086896 NZ_AP023307.1 JFGLBHGK_00006 NZ_AP023307.1__JFGLBHGK_00006 NZ_AP023307.1 C371 JFGLBHGK_00006 ARO:3000186 tet(M) Tet(M) is a ribosomal protection protein that confers tetracycline resistance. It is found on transposable DNA elements and its horizontal transfer between bacterial species has been documented. tetracycline-resistant ribosomal protection protein 96.1 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 286 M0086897 NZ_AP023307.1 JFGLBHGK_00006 NZ_AP023307.1__JFGLBHGK_00006 NZ_AP023307.1 C371 JFGLBHGK_00006 ARO:3000186 tet(M) Tet(M) is a ribosomal protection protein that confers tetracycline resistance. It is found on transposable DNA elements and its horizontal transfer between bacterial species has been documented. tetracycline-resistant ribosomal protection protein 96.1 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 287 M0086898 NZ_AP023307.1 JFGLBHGK_00006 NZ_AP023307.1__JFGLBHGK_00006 NZ_AP023307.1 C371 JFGLBHGK_00006 ARO:3000186 tet(M) Tet(M) is a ribosomal protection protein that confers tetracycline resistance. It is found on transposable DNA elements and its horizontal transfer between bacterial species has been documented. tetracycline-resistant ribosomal protection protein 96.1 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 288 M0086899 NZ_AP023307.1 JFGLBHGK_00006 NZ_AP023307.1__JFGLBHGK_00006 NZ_AP023307.1 C371 JFGLBHGK_00006 ARO:3000186 tet(M) Tet(M) is a ribosomal protection protein that confers tetracycline resistance. It is found on transposable DNA elements and its horizontal transfer between bacterial species has been documented. tetracycline-resistant ribosomal protection protein 96.1 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 289 M0086900 NZ_AP023307.1 JFGLBHGK_00006 NZ_AP023307.1__JFGLBHGK_00006 NZ_AP023307.1 C371 JFGLBHGK_00006 ARO:3000186 tet(M) Tet(M) is a ribosomal protection protein that confers tetracycline resistance. It is found on transposable DNA elements and its horizontal transfer between bacterial species has been documented. tetracycline-resistant ribosomal protection protein 96.1 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 290 M0086901 NZ_AP023307.1 JFGLBHGK_00006 NZ_AP023307.1__JFGLBHGK_00006 NZ_AP023307.1 C371 JFGLBHGK_00006 ARO:3000186 tet(M) Tet(M) is a ribosomal protection protein that confers tetracycline resistance. It is found on transposable DNA elements and its horizontal transfer between bacterial species has been documented. tetracycline-resistant ribosomal protection protein 96.1 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 291 M0086902 NZ_AP023307.1 JFGLBHGK_00006 NZ_AP023307.1__JFGLBHGK_00006 NZ_AP023307.1 C371 JFGLBHGK_00006 ARO:3000186 tet(M) Tet(M) is a ribosomal protection protein that confers tetracycline resistance. It is found on transposable DNA elements and its horizontal transfer between bacterial species has been documented. tetracycline-resistant ribosomal protection protein 96.1 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 292 M0086903 NZ_AP023307.1 JFGLBHGK_00006 NZ_AP023307.1__JFGLBHGK_00006 NZ_AP023307.1 C371 JFGLBHGK_00006 ARO:3000186 tet(M) Tet(M) is a ribosomal protection protein that confers tetracycline resistance. It is found on transposable DNA elements and its horizontal transfer between bacterial species has been documented. tetracycline-resistant ribosomal protection protein 96.1 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 293 M0086904 NZ_AP023307.1 JFGLBHGK_00006 NZ_AP023307.1__JFGLBHGK_00006 NZ_AP023307.1 C371 JFGLBHGK_00006 ARO:3000186 tet(M) Tet(M) is a ribosomal protection protein that confers tetracycline resistance. It is found on transposable DNA elements and its horizontal transfer between bacterial species has been documented. tetracycline-resistant ribosomal protection protein 96.1 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 294 M0086905 NZ_AP023307.1 JFGLBHGK_00006 NZ_AP023307.1__JFGLBHGK_00006 NZ_AP023307.1 C371 JFGLBHGK_00006 ARO:3000186 tet(M) Tet(M) is a ribosomal protection protein that confers tetracycline resistance. It is found on transposable DNA elements and its horizontal transfer between bacterial species has been documented. tetracycline-resistant ribosomal protection protein 96.1 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 295 M0086906 NZ_AP023307.1 JFGLBHGK_00006 NZ_AP023307.1__JFGLBHGK_00006 NZ_AP023307.1 C371 JFGLBHGK_00006 ARO:3000186 tet(M) Tet(M) is a ribosomal protection protein that confers tetracycline resistance. It is found on transposable DNA elements and its horizontal transfer between bacterial species has been documented. tetracycline-resistant ribosomal protection protein 96.1 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 296 M0086907 NZ_AP023307.1 JFGLBHGK_00006 NZ_AP023307.1__JFGLBHGK_00006 NZ_AP023307.1 C371 JFGLBHGK_00006 ARO:3000186 tet(M) Tet(M) is a ribosomal protection protein that confers tetracycline resistance. It is found on transposable DNA elements and its horizontal transfer between bacterial species has been documented. tetracycline-resistant ribosomal protection protein 96.1 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 297 M0086908 NZ_AP023307.1 JFGLBHGK_00006 NZ_AP023307.1__JFGLBHGK_00006 NZ_AP023307.1 C371 JFGLBHGK_00006 ARO:3000186 tet(M) Tet(M) is a ribosomal protection protein that confers tetracycline resistance. It is found on transposable DNA elements and its horizontal transfer between bacterial species has been documented. tetracycline-resistant ribosomal protection protein 96.1 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 298 M0086909 NZ_AP023307.1 JFGLBHGK_00006 NZ_AP023307.1__JFGLBHGK_00006 NZ_AP023307.1 C371 JFGLBHGK_00006 ARO:3000186 tet(M) Tet(M) is a ribosomal protection protein that confers tetracycline resistance. It is found on transposable DNA elements and its horizontal transfer between bacterial species has been documented. tetracycline-resistant ribosomal protection protein 96.1 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 299 M0086910 NZ_AP023307.1 JFGLBHGK_00006 NZ_AP023307.1__JFGLBHGK_00006 NZ_AP023307.1 C371 JFGLBHGK_00006 ARO:3000186 tet(M) Tet(M) is a ribosomal protection protein that confers tetracycline resistance. It is found on transposable DNA elements and its horizontal transfer between bacterial species has been documented. tetracycline-resistant ribosomal protection protein 96.1 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 300 M0086911 NZ_AP023307.1 JFGLBHGK_00006 NZ_AP023307.1__JFGLBHGK_00006 NZ_AP023307.1 C371 JFGLBHGK_00006 ARO:3000186 tet(M) Tet(M) is a ribosomal protection protein that confers tetracycline resistance. It is found on transposable DNA elements and its horizontal transfer between bacterial species has been documented. tetracycline-resistant ribosomal protection protein 96.1 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 301 M0086912 NZ_AP023307.1 JFGLBHGK_00006 NZ_AP023307.1__JFGLBHGK_00006 NZ_AP023307.1 C371 JFGLBHGK_00006 ARO:3000186 tet(M) Tet(M) is a ribosomal protection protein that confers tetracycline resistance. It is found on transposable DNA elements and its horizontal transfer between bacterial species has been documented. tetracycline-resistant ribosomal protection protein 96.1 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 302 M0086913 NZ_AP023307.1 JFGLBHGK_00006 NZ_AP023307.1__JFGLBHGK_00006 NZ_AP023307.1 C371 JFGLBHGK_00006 ARO:3000186 tet(M) Tet(M) is a ribosomal protection protein that confers tetracycline resistance. It is found on transposable DNA elements and its horizontal transfer between bacterial species has been documented. tetracycline-resistant ribosomal protection protein 96.1 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 303 M0086914 NZ_AP023307.1 JFGLBHGK_00006 NZ_AP023307.1__JFGLBHGK_00006 NZ_AP023307.1 C371 JFGLBHGK_00006 ARO:3000186 tet(M) Tet(M) is a ribosomal protection protein that confers tetracycline resistance. It is found on transposable DNA elements and its horizontal transfer between bacterial species has been documented. tetracycline-resistant ribosomal protection protein 96.1 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 304 M0086982 NZ_AP024950.1 IBHAHPKB_00022 NZ_AP024950.1__IBHAHPKB_00022 NZ_AP024950.1 C379 IBHAHPKB_00022 ARO:3004239 NPS-1 NPS-1 is a plasmid-encoded class D beta-lactamases identified from two Pseudomonas aeruginosa isolates in 1986. NPS beta-lactamase 98.8 4.5e-189 1 260 1.0 1 cephalosporin antibiotic inactivation 305 M0096172 NZ_CP040561.1 PNGAHLAO_00024 NZ_CP040561.1__PNGAHLAO_00024 NZ_CP040561.1 C639 PNGAHLAO_00024 ARO:3000319 mphC The mphC gene was identified from Staphylococcus aureus. This gene shows similarity to mphB gene from Escherchia coli. macrolide phosphotransferase (MPH) 98.7 1.82e-228 1 299 1.0 1 macrolide antibiotic antibiotic inactivation 306 M0096173 NZ_CP040734.1 BKPCKCLO_00023 NZ_CP040734.1__BKPCKCLO_00023 NZ_CP040734.1 C641 BKPCKCLO_00023 ARO:3000251 msrA MsrA is an ABC-F subfamily ribosomal protection protein expressed in Staphylococcus species which confers resistance to erythromycin and streptogramin B antibiotics through antibiotic target protection mechanisms. It is associated with plasmid DNA. msr-type ABC-F protein 97.5 0 1 488 1.0 1 macrolide antibiotic antibiotic target protection 307 M0097264 NZ_CP045917.1 KMEIDAKP_00448 NZ_CP045917.1__KMEIDAKP_00448 NZ_CP045917.1 C672 KMEIDAKP_00448 ARO:3002639 APH(3'')-Ib APH(3'')-Ib is an aminoglycoside phosphotransferase encoded by plasmids, transposons, integrative conjugative elements and chromosomes in Enterobacteriaceae and Pseudomonas spp. APH(3'') 100 3.6e-203 1 267 1.0 1 aminoglycoside antibiotic antibiotic inactivation 308 M0099074 NZ_CP049911.1 IKFCJDKM_00142 NZ_CP049911.1__IKFCJDKM_00142 NZ_CP049911.1 C706 IKFCJDKM_00142 ARO:3000410 sul1 Sul1 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria. It is linked to other resistance genes of class 1 integrons. sulfonamide resistant sul 100 2e-198 6 283 0.9823321554770318 0.996415770609319 sulfonamide antibiotic antibiotic target replacement 309 M0101062 NZ_CP054007.1 ENMLDDLB_00019 NZ_CP054007.1__ENMLDDLB_00019 NZ_CP054007.1 C742 ENMLDDLB_00019 ARO:3003046 qacA qacA is a subunit of the qac multidrug efflux pump. major facilitator superfamily (MFS) antibiotic efflux pump 99 0 1 514 1.0 1 fluoroquinolone antibiotic antibiotic efflux 310 M0101112 NZ_CP059303.1 IGLJDEHD_00001 NZ_CP059303.1__IGLJDEHD_00001 NZ_CP059303.1 C765 IGLJDEHD_00001 ARO:3000566 tet(39) Tet39 is a tetracycline efflux pump found in Gram-negative bacteria, including Brevundimonas, Stenotrophomonas, Enterobacter, Alcaligenes, Acinetobacter, and Providencia. major facilitator superfamily (MFS) antibiotic efflux pump 100 1.26e-264 1 373 1.0 0.944303797468354 tetracycline antibiotic antibiotic efflux 311 M0101113 NZ_CP059303.1 IGLJDEHD_00001 NZ_CP059303.1__IGLJDEHD_00001 NZ_CP059303.1 C765 IGLJDEHD_00001 ARO:3000566 tet(39) Tet39 is a tetracycline efflux pump found in Gram-negative bacteria, including Brevundimonas, Stenotrophomonas, Enterobacter, Alcaligenes, Acinetobacter, and Providencia. major facilitator superfamily (MFS) antibiotic efflux pump 100 1.26e-264 1 373 1.0 0.944303797468354 tetracycline antibiotic antibiotic efflux 312 M0101114 NZ_CP059303.1 IGLJDEHD_00001 NZ_CP059303.1__IGLJDEHD_00001 NZ_CP059303.1 C765 IGLJDEHD_00001 ARO:3000566 tet(39) Tet39 is a tetracycline efflux pump found in Gram-negative bacteria, including Brevundimonas, Stenotrophomonas, Enterobacter, Alcaligenes, Acinetobacter, and Providencia. major facilitator superfamily (MFS) antibiotic efflux pump 100 1.26e-264 1 373 1.0 0.944303797468354 tetracycline antibiotic antibiotic efflux 313 M0101115 NZ_CP059303.1 IGLJDEHD_00001 NZ_CP059303.1__IGLJDEHD_00001 NZ_CP059303.1 C765 IGLJDEHD_00001 ARO:3000566 tet(39) Tet39 is a tetracycline efflux pump found in Gram-negative bacteria, including Brevundimonas, Stenotrophomonas, Enterobacter, Alcaligenes, Acinetobacter, and Providencia. major facilitator superfamily (MFS) antibiotic efflux pump 100 1.26e-264 1 373 1.0 0.944303797468354 tetracycline antibiotic antibiotic efflux 314 M0101131 NZ_CP059303.1 IGLJDEHD_00001 NZ_CP059303.1__IGLJDEHD_00001 NZ_CP059303.1 C765 IGLJDEHD_00001 ARO:3000566 tet(39) Tet39 is a tetracycline efflux pump found in Gram-negative bacteria, including Brevundimonas, Stenotrophomonas, Enterobacter, Alcaligenes, Acinetobacter, and Providencia. major facilitator superfamily (MFS) antibiotic efflux pump 100 1.26e-264 1 373 1.0 0.944303797468354 tetracycline antibiotic antibiotic efflux 315 M0101132 NZ_CP059303.1 IGLJDEHD_00001 NZ_CP059303.1__IGLJDEHD_00001 NZ_CP059303.1 C765 IGLJDEHD_00001 ARO:3000566 tet(39) Tet39 is a tetracycline efflux pump found in Gram-negative bacteria, including Brevundimonas, Stenotrophomonas, Enterobacter, Alcaligenes, Acinetobacter, and Providencia. major facilitator superfamily (MFS) antibiotic efflux pump 100 1.26e-264 1 373 1.0 0.944303797468354 tetracycline antibiotic antibiotic efflux 316 M0101133 NZ_CP059303.1 IGLJDEHD_00001 NZ_CP059303.1__IGLJDEHD_00001 NZ_CP059303.1 C765 IGLJDEHD_00001 ARO:3000566 tet(39) Tet39 is a tetracycline efflux pump found in Gram-negative bacteria, including Brevundimonas, Stenotrophomonas, Enterobacter, Alcaligenes, Acinetobacter, and Providencia. major facilitator superfamily (MFS) antibiotic efflux pump 100 1.26e-264 1 373 1.0 0.944303797468354 tetracycline antibiotic antibiotic efflux 317 M0104318 NZ_CP069477.1 HNKODPLL_00002 NZ_CP069477.1__HNKODPLL_00002 NZ_CP069477.1 C835 HNKODPLL_00002 ARO:3002829 vgaA vgaA is an ABC-F subfamily protein expressed in staphylococci that confers resistance to streptogramin A antibiotics and related compounds. It is associated with plasmid DNA. vga-type ABC-F protein 99.2 0 1 522 1.0 1 lincosamide antibiotic antibiotic target protection 318 M0104438 NZ_CP070061.1 NJPBBPMF_00003 NZ_CP070061.1__NJPBBPMF_00003 NZ_CP070061.1 C852 NJPBBPMF_00003 ARO:3000521 Staphylococcus aureus mupA conferring resistance to mupirocin An alternative isoleucyl-tRNA synthetase conferring resistance to mupirocin. antibiotic-resistant isoleucyl-tRNA synthetase (ileS) 99.5 0 1 1024 1.0 1 mupirocin-like antibiotic antibiotic target alteration 319 M0104472 NZ_CP071314.1 KLINOBFJ_00035 NZ_CP071314.1__KLINOBFJ_00035 NZ_CP071314.1 C860 KLINOBFJ_00035 ARO:3002660 APH(6)-Id APH(6)-Id is an aminoglycoside phosphotransferase encoded by plasmids, integrative conjugative elements and chromosomal genomic islands in K. pneumoniae, Salmonella spp., E. coli, Shigella flexneri, Providencia alcalifaciens, Pseudomonas spp., V. cholerae, Edwardsiella tarda, Pasteurella multocida and Aeromonas bestiarum. APH(6) 99.6 1.07e-205 1 278 1.0 1 aminoglycoside antibiotic antibiotic inactivation 320 M0105057 NZ_CP084442.1 DNBIKNCJ_00016 NZ_CP084442.1__DNBIKNCJ_00016 NZ_CP084442.1 C961 DNBIKNCJ_00016 ARO:3008823 PC1 BlaZ family penicillin-hydrolyzing class A beta-lactamase PC1. BlaZ beta-lactamase 97.5 1.43e-191 1 281 1.0 1 penicillin beta-lactam antibiotic inactivation 321 M0105343 NZ_CP090012.1 JIOAFOCJ_00005 NZ_CP090012.1__JIOAFOCJ_00005 NZ_CP090012.1 C984 JIOAFOCJ_00005 ARO:3000251 msrA MsrA is an ABC-F subfamily ribosomal protection protein expressed in Staphylococcus species which confers resistance to erythromycin and streptogramin B antibiotics through antibiotic target protection mechanisms. It is associated with plasmid DNA. msr-type ABC-F protein 97.5 0 1 488 1.0 1 macrolide antibiotic antibiotic target protection 322 M0105364 NZ_CP090013.1 DHGPAPEB_00004 NZ_CP090013.1__DHGPAPEB_00004 NZ_CP090013.1 C985 DHGPAPEB_00004 ARO:3003046 qacA qacA is a subunit of the qac multidrug efflux pump. major facilitator superfamily (MFS) antibiotic efflux pump 99.8 0 1 514 1.0 1 fluoroquinolone antibiotic antibiotic efflux 323 M0105365 NZ_CP090013.1 DHGPAPEB_00004 NZ_CP090013.1__DHGPAPEB_00004 NZ_CP090013.1 C985 DHGPAPEB_00004 ARO:3003046 qacA qacA is a subunit of the qac multidrug efflux pump. major facilitator superfamily (MFS) antibiotic efflux pump 99.8 0 1 514 1.0 1 fluoroquinolone antibiotic antibiotic efflux 324 M0105366 NZ_CP090013.1 DHGPAPEB_00004 NZ_CP090013.1__DHGPAPEB_00004 NZ_CP090013.1 C985 DHGPAPEB_00004 ARO:3003046 qacA qacA is a subunit of the qac multidrug efflux pump. major facilitator superfamily (MFS) antibiotic efflux pump 99.8 0 1 514 1.0 1 fluoroquinolone antibiotic antibiotic efflux 325 M0105367 NZ_CP090013.1 DHGPAPEB_00004 NZ_CP090013.1__DHGPAPEB_00004 NZ_CP090013.1 C985 DHGPAPEB_00004 ARO:3003046 qacA qacA is a subunit of the qac multidrug efflux pump. major facilitator superfamily (MFS) antibiotic efflux pump 99.8 0 1 514 1.0 1 fluoroquinolone antibiotic antibiotic efflux 326 M0105370 NZ_CP090013.1 DHGPAPEB_00004 NZ_CP090013.1__DHGPAPEB_00004 NZ_CP090013.1 C985 DHGPAPEB_00004 ARO:3003046 qacA qacA is a subunit of the qac multidrug efflux pump. major facilitator superfamily (MFS) antibiotic efflux pump 99.8 0 1 514 1.0 1 fluoroquinolone antibiotic antibiotic efflux 327 M0105373 NZ_CP090015.1 LEFBECIM_00007 NZ_CP090015.1__LEFBECIM_00007 NZ_CP090015.1 C986 LEFBECIM_00007 ARO:3003046 qacA qacA is a subunit of the qac multidrug efflux pump. major facilitator superfamily (MFS) antibiotic efflux pump 99.4 0 1 514 1.0 1 fluoroquinolone antibiotic antibiotic efflux 328 M0105374 NZ_CP090015.1 LEFBECIM_00007 NZ_CP090015.1__LEFBECIM_00007 NZ_CP090015.1 C986 LEFBECIM_00007 ARO:3003046 qacA qacA is a subunit of the qac multidrug efflux pump. major facilitator superfamily (MFS) antibiotic efflux pump 99.4 0 1 514 1.0 1 fluoroquinolone antibiotic antibiotic efflux 329 M0105376 NZ_CP090015.1 LEFBECIM_00012 NZ_CP090015.1__LEFBECIM_00012 NZ_CP090015.1 C986 LEFBECIM_00012 ARO:3000251 msrA MsrA is an ABC-F subfamily ribosomal protection protein expressed in Staphylococcus species which confers resistance to erythromycin and streptogramin B antibiotics through antibiotic target protection mechanisms. It is associated with plasmid DNA. msr-type ABC-F protein 95.5 4.20005205529644e-320 1 488 1.0 1 macrolide antibiotic antibiotic target protection 330 M0105377 NZ_CP090015.1 LEFBECIM_00007 NZ_CP090015.1__LEFBECIM_00007 NZ_CP090015.1 C986 LEFBECIM_00007 ARO:3003046 qacA qacA is a subunit of the qac multidrug efflux pump. major facilitator superfamily (MFS) antibiotic efflux pump 99.4 0 1 514 1.0 1 fluoroquinolone antibiotic antibiotic efflux 331 M0106619 NZ_CP093209.1 PJHDJKOI_00007 NZ_CP093209.1__PJHDJKOI_00007 NZ_CP093209.1 C1008 PJHDJKOI_00007 ARO:3008823 PC1 BlaZ family penicillin-hydrolyzing class A beta-lactamase PC1. BlaZ beta-lactamase 97.9 3.52e-192 1 281 1.0 1 penicillin beta-lactam antibiotic inactivation 332 M0106620 NZ_CP093209.1 PJHDJKOI_00007 NZ_CP093209.1__PJHDJKOI_00007 NZ_CP093209.1 C1008 PJHDJKOI_00007 ARO:3008823 PC1 BlaZ family penicillin-hydrolyzing class A beta-lactamase PC1. BlaZ beta-lactamase 97.9 3.52e-192 1 281 1.0 1 penicillin beta-lactam antibiotic inactivation 333 M0106654 NZ_CP095105.1 BMGGOLPK_00014 NZ_CP095105.1__BMGGOLPK_00014 NZ_CP095105.1 C1015 BMGGOLPK_00014 ARO:3002829 vgaA vgaA is an ABC-F subfamily protein expressed in staphylococci that confers resistance to streptogramin A antibiotics and related compounds. It is associated with plasmid DNA. vga-type ABC-F protein 97.9 0 1 522 1.0 1 lincosamide antibiotic antibiotic target protection 334 M0106655 NZ_CP095105.1 BMGGOLPK_00014 NZ_CP095105.1__BMGGOLPK_00014 NZ_CP095105.1 C1015 BMGGOLPK_00014 ARO:3002829 vgaA vgaA is an ABC-F subfamily protein expressed in staphylococci that confers resistance to streptogramin A antibiotics and related compounds. It is associated with plasmid DNA. vga-type ABC-F protein 97.9 0 1 522 1.0 1 lincosamide antibiotic antibiotic target protection 335 M0106656 NZ_CP095105.1 BMGGOLPK_00014 NZ_CP095105.1__BMGGOLPK_00014 NZ_CP095105.1 C1015 BMGGOLPK_00014 ARO:3002829 vgaA vgaA is an ABC-F subfamily protein expressed in staphylococci that confers resistance to streptogramin A antibiotics and related compounds. It is associated with plasmid DNA. vga-type ABC-F protein 97.9 0 1 522 1.0 1 lincosamide antibiotic antibiotic target protection 336 M0106657 NZ_CP095105.1 BMGGOLPK_00014 NZ_CP095105.1__BMGGOLPK_00014 NZ_CP095105.1 C1015 BMGGOLPK_00014 ARO:3002829 vgaA vgaA is an ABC-F subfamily protein expressed in staphylococci that confers resistance to streptogramin A antibiotics and related compounds. It is associated with plasmid DNA. vga-type ABC-F protein 97.9 0 1 522 1.0 1 lincosamide antibiotic antibiotic target protection 337 M0106658 NZ_CP095105.1 BMGGOLPK_00014 NZ_CP095105.1__BMGGOLPK_00014 NZ_CP095105.1 C1015 BMGGOLPK_00014 ARO:3002829 vgaA vgaA is an ABC-F subfamily protein expressed in staphylococci that confers resistance to streptogramin A antibiotics and related compounds. It is associated with plasmid DNA. vga-type ABC-F protein 97.9 0 1 522 1.0 1 lincosamide antibiotic antibiotic target protection 338 M0106659 NZ_CP095105.1 BMGGOLPK_00014 NZ_CP095105.1__BMGGOLPK_00014 NZ_CP095105.1 C1015 BMGGOLPK_00014 ARO:3002829 vgaA vgaA is an ABC-F subfamily protein expressed in staphylococci that confers resistance to streptogramin A antibiotics and related compounds. It is associated with plasmid DNA. vga-type ABC-F protein 97.9 0 1 522 1.0 1 lincosamide antibiotic antibiotic target protection 339 M0106660 NZ_CP095105.1 BMGGOLPK_00014 NZ_CP095105.1__BMGGOLPK_00014 NZ_CP095105.1 C1015 BMGGOLPK_00014 ARO:3002829 vgaA vgaA is an ABC-F subfamily protein expressed in staphylococci that confers resistance to streptogramin A antibiotics and related compounds. It is associated with plasmid DNA. vga-type ABC-F protein 97.9 0 1 522 1.0 1 lincosamide antibiotic antibiotic target protection 340 M0106661 NZ_CP095105.1 BMGGOLPK_00014 NZ_CP095105.1__BMGGOLPK_00014 NZ_CP095105.1 C1015 BMGGOLPK_00014 ARO:3002829 vgaA vgaA is an ABC-F subfamily protein expressed in staphylococci that confers resistance to streptogramin A antibiotics and related compounds. It is associated with plasmid DNA. vga-type ABC-F protein 97.9 0 1 522 1.0 1 lincosamide antibiotic antibiotic target protection 341 M0106662 NZ_CP095105.1 BMGGOLPK_00014 NZ_CP095105.1__BMGGOLPK_00014 NZ_CP095105.1 C1015 BMGGOLPK_00014 ARO:3002829 vgaA vgaA is an ABC-F subfamily protein expressed in staphylococci that confers resistance to streptogramin A antibiotics and related compounds. It is associated with plasmid DNA. vga-type ABC-F protein 97.9 0 1 522 1.0 1 lincosamide antibiotic antibiotic target protection 342 M0106663 NZ_CP095105.1 BMGGOLPK_00014 NZ_CP095105.1__BMGGOLPK_00014 NZ_CP095105.1 C1015 BMGGOLPK_00014 ARO:3002829 vgaA vgaA is an ABC-F subfamily protein expressed in staphylococci that confers resistance to streptogramin A antibiotics and related compounds. It is associated with plasmid DNA. vga-type ABC-F protein 97.9 0 1 522 1.0 1 lincosamide antibiotic antibiotic target protection 343 M0106664 NZ_CP095105.1 BMGGOLPK_00014 NZ_CP095105.1__BMGGOLPK_00014 NZ_CP095105.1 C1015 BMGGOLPK_00014 ARO:3002829 vgaA vgaA is an ABC-F subfamily protein expressed in staphylococci that confers resistance to streptogramin A antibiotics and related compounds. It is associated with plasmid DNA. vga-type ABC-F protein 97.9 0 1 522 1.0 1 lincosamide antibiotic antibiotic target protection 344 M0106665 NZ_CP095105.1 BMGGOLPK_00014 NZ_CP095105.1__BMGGOLPK_00014 NZ_CP095105.1 C1015 BMGGOLPK_00014 ARO:3002829 vgaA vgaA is an ABC-F subfamily protein expressed in staphylococci that confers resistance to streptogramin A antibiotics and related compounds. It is associated with plasmid DNA. vga-type ABC-F protein 97.9 0 1 522 1.0 1 lincosamide antibiotic antibiotic target protection 345 M0106666 NZ_CP095105.1 BMGGOLPK_00014 NZ_CP095105.1__BMGGOLPK_00014 NZ_CP095105.1 C1015 BMGGOLPK_00014 ARO:3002829 vgaA vgaA is an ABC-F subfamily protein expressed in staphylococci that confers resistance to streptogramin A antibiotics and related compounds. It is associated with plasmid DNA. vga-type ABC-F protein 97.9 0 1 522 1.0 1 lincosamide antibiotic antibiotic target protection 346 M0106667 NZ_CP095105.1 BMGGOLPK_00014 NZ_CP095105.1__BMGGOLPK_00014 NZ_CP095105.1 C1015 BMGGOLPK_00014 ARO:3002829 vgaA vgaA is an ABC-F subfamily protein expressed in staphylococci that confers resistance to streptogramin A antibiotics and related compounds. It is associated with plasmid DNA. vga-type ABC-F protein 97.9 0 1 522 1.0 1 lincosamide antibiotic antibiotic target protection 347 M0106668 NZ_CP095105.1 BMGGOLPK_00014 NZ_CP095105.1__BMGGOLPK_00014 NZ_CP095105.1 C1015 BMGGOLPK_00014 ARO:3002829 vgaA vgaA is an ABC-F subfamily protein expressed in staphylococci that confers resistance to streptogramin A antibiotics and related compounds. It is associated with plasmid DNA. vga-type ABC-F protein 97.9 0 1 522 1.0 1 lincosamide antibiotic antibiotic target protection 348 M0106717 NZ_CP096541.1 FBNENCCH_00006 NZ_CP096541.1__FBNENCCH_00006 NZ_CP096541.1 C1022 FBNENCCH_00006 ARO:3003441 cfrA CfrA is a chloramphenicol-florfenicol resistance gene and methyltransferase enzyme. Methylation of position 8 of A2503 in 23S rRNA confers resistance to chloramphenicol antibiotics first identified by Schwarz 2000 as cfr from Mammaliicoccus sciuri. Additional Oxazolidinone resistance mediated by the cfr gene in a human isolated was first reported from Colombia in linezolid- and methicillin-resistant Staphylococcus aureus. Cfr 23S ribosomal RNA methyltransferase 100 1.68e-256 1 349 1.0 1 lincosamide antibiotic antibiotic target alteration 349 M0106718 NZ_CP096541.1 FBNENCCH_00012 NZ_CP096541.1__FBNENCCH_00012 NZ_CP096541.1 C1022 FBNENCCH_00012 ARO:3000375 ErmB ErmB confers the MLSb phenotype. Similar to ErmC, expression of ErmB is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present, it binds the leader peptide causing a change in conformation allowing for the expression of ErmB. Erm 23S ribosomal RNA methyltransferase 98 3.24e-173 1 245 1.0 0.987903225806452 macrolide antibiotic antibiotic target alteration 350 M0106719 NZ_CP096541.1 FBNENCCH_00012 NZ_CP096541.1__FBNENCCH_00012 NZ_CP096541.1 C1022 FBNENCCH_00012 ARO:3000375 ErmB ErmB confers the MLSb phenotype. Similar to ErmC, expression of ErmB is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present, it binds the leader peptide causing a change in conformation allowing for the expression of ErmB. Erm 23S ribosomal RNA methyltransferase 98 3.24e-173 1 245 1.0 0.987903225806452 macrolide antibiotic antibiotic target alteration 351 M0106720 NZ_CP096541.1 FBNENCCH_00012 NZ_CP096541.1__FBNENCCH_00012 NZ_CP096541.1 C1022 FBNENCCH_00012 ARO:3000375 ErmB ErmB confers the MLSb phenotype. Similar to ErmC, expression of ErmB is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present, it binds the leader peptide causing a change in conformation allowing for the expression of ErmB. Erm 23S ribosomal RNA methyltransferase 98 3.24e-173 1 245 1.0 0.987903225806452 macrolide antibiotic antibiotic target alteration 352 M0106855 NZ_CP098821.1 EFLHLBLD_00042 NZ_CP098821.1__EFLHLBLD_00042 NZ_CP098821.1 C1034 EFLHLBLD_00042 ARO:3008823 PC1 BlaZ family penicillin-hydrolyzing class A beta-lactamase PC1. BlaZ beta-lactamase 97.9 5e-192 1 281 1.0 1 penicillin beta-lactam antibiotic inactivation 353 M0106856 NZ_CP098821.1 EFLHLBLD_00042 NZ_CP098821.1__EFLHLBLD_00042 NZ_CP098821.1 C1034 EFLHLBLD_00042 ARO:3008823 PC1 BlaZ family penicillin-hydrolyzing class A beta-lactamase PC1. BlaZ beta-lactamase 97.9 5e-192 1 281 1.0 1 penicillin beta-lactam antibiotic inactivation 354 M0106857 NZ_CP098821.1 EFLHLBLD_00042 NZ_CP098821.1__EFLHLBLD_00042 NZ_CP098821.1 C1034 EFLHLBLD_00042 ARO:3008823 PC1 BlaZ family penicillin-hydrolyzing class A beta-lactamase PC1. BlaZ beta-lactamase 97.9 5e-192 1 281 1.0 1 penicillin beta-lactam antibiotic inactivation 355 M0106858 NZ_CP098821.1 EFLHLBLD_00042 NZ_CP098821.1__EFLHLBLD_00042 NZ_CP098821.1 C1034 EFLHLBLD_00042 ARO:3008823 PC1 BlaZ family penicillin-hydrolyzing class A beta-lactamase PC1. BlaZ beta-lactamase 97.9 5e-192 1 281 1.0 1 penicillin beta-lactam antibiotic inactivation 356 M0106859 NZ_CP098821.1 EFLHLBLD_00042 NZ_CP098821.1__EFLHLBLD_00042 NZ_CP098821.1 C1034 EFLHLBLD_00042 ARO:3008823 PC1 BlaZ family penicillin-hydrolyzing class A beta-lactamase PC1. BlaZ beta-lactamase 97.9 5e-192 1 281 1.0 1 penicillin beta-lactam antibiotic inactivation 357 M0106860 NZ_CP098821.1 EFLHLBLD_00042 NZ_CP098821.1__EFLHLBLD_00042 NZ_CP098821.1 C1034 EFLHLBLD_00042 ARO:3008823 PC1 BlaZ family penicillin-hydrolyzing class A beta-lactamase PC1. BlaZ beta-lactamase 97.9 5e-192 1 281 1.0 1 penicillin beta-lactam antibiotic inactivation 358 M0106861 NZ_CP098821.1 EFLHLBLD_00042 NZ_CP098821.1__EFLHLBLD_00042 NZ_CP098821.1 C1034 EFLHLBLD_00042 ARO:3008823 PC1 BlaZ family penicillin-hydrolyzing class A beta-lactamase PC1. BlaZ beta-lactamase 97.9 5e-192 1 281 1.0 1 penicillin beta-lactam antibiotic inactivation 359 M0106866 NZ_CP098821.1 EFLHLBLD_00042 NZ_CP098821.1__EFLHLBLD_00042 NZ_CP098821.1 C1034 EFLHLBLD_00042 ARO:3008823 PC1 BlaZ family penicillin-hydrolyzing class A beta-lactamase PC1. BlaZ beta-lactamase 97.9 5e-192 1 281 1.0 1 penicillin beta-lactam antibiotic inactivation 360 M0106912 NZ_CP104280.1 AKDFDHLG_00020 NZ_CP104280.1__AKDFDHLG_00020 NZ_CP104280.1 C1073 AKDFDHLG_00020 ARO:3002703 cmx cmx is a plasmid or transposon-encoded chloramphenicol exporter that is found in Corynebacterium striatum and Pseudomonas aeruginosa. major facilitator superfamily (MFS) antibiotic efflux pump 99.7 2.43e-252 1 391 1.0 1 phenicol antibiotic antibiotic efflux 361 M0106913 NZ_CP104280.1 AKDFDHLG_00020 NZ_CP104280.1__AKDFDHLG_00020 NZ_CP104280.1 C1073 AKDFDHLG_00020 ARO:3002703 cmx cmx is a plasmid or transposon-encoded chloramphenicol exporter that is found in Corynebacterium striatum and Pseudomonas aeruginosa. major facilitator superfamily (MFS) antibiotic efflux pump 99.7 2.43e-252 1 391 1.0 1 phenicol antibiotic antibiotic efflux 362 M0109478 NZ_CP118846.1 JCMBGFDL_00049 NZ_CP118846.1__JCMBGFDL_00049 NZ_CP118846.1 C1127 JCMBGFDL_00049 ARO:3002865 dfrC dfrC is a chromosome-encoded dihydrofolate reductase found in Staphylococcus aureus. trimethoprim resistant dihydrofolate reductase dfr 80.4 1.35e-95 1 158 1.0 0.981366459627329 diaminopyrimidine antibiotic antibiotic target replacement 363 M0109543 NZ_CP118944.1 LNEGBHAO_00037 NZ_CP118944.1__LNEGBHAO_00037 NZ_CP118944.1 C1128 LNEGBHAO_00037 ARO:3002639 APH(3'')-Ib APH(3'')-Ib is an aminoglycoside phosphotransferase encoded by plasmids, transposons, integrative conjugative elements and chromosomes in Enterobacteriaceae and Pseudomonas spp. APH(3'') 99.6 5.98e-202 1 267 1.0 1 aminoglycoside antibiotic antibiotic inactivation 364 M0109544 NZ_CP118944.1 LNEGBHAO_00038 NZ_CP118944.1__LNEGBHAO_00038 NZ_CP118944.1 C1128 LNEGBHAO_00038 ARO:3002660 APH(6)-Id APH(6)-Id is an aminoglycoside phosphotransferase encoded by plasmids, integrative conjugative elements and chromosomal genomic islands in K. pneumoniae, Salmonella spp., E. coli, Shigella flexneri, Providencia alcalifaciens, Pseudomonas spp., V. cholerae, Edwardsiella tarda, Pasteurella multocida and Aeromonas bestiarum. APH(6) 99.6 1.07e-205 1 278 1.0 1 aminoglycoside antibiotic antibiotic inactivation 365 M0109570 NZ_CP119342.1 IHNPCGDK_00023 NZ_CP119342.1__IHNPCGDK_00023 NZ_CP119342.1 C1133 IHNPCGDK_00023 ARO:3000621 PC1 beta-lactamase (blaZ) The blaZ beta-lactamase is found in Bacillus subtilis and Staphylococcus aureus. BlaZ beta-lactamase 95 7.61e-187 1 281 1.0 1 penicillin beta-lactam antibiotic inactivation 366 M0109571 NZ_CP119342.1 IHNPCGDK_00023 NZ_CP119342.1__IHNPCGDK_00023 NZ_CP119342.1 C1133 IHNPCGDK_00023 ARO:3000621 PC1 beta-lactamase (blaZ) The blaZ beta-lactamase is found in Bacillus subtilis and Staphylococcus aureus. BlaZ beta-lactamase 95 7.61e-187 1 281 1.0 1 penicillin beta-lactam antibiotic inactivation 367 M0110865 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 368 M0110866 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 369 M0110867 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 370 M0110868 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 371 M0110869 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 372 M0110870 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 373 M0110871 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 374 M0110872 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 375 M0110873 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 376 M0110874 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 377 M0110875 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 378 M0110876 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 379 M0110877 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 380 M0110878 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 381 M0110879 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 382 M0110880 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 383 M0110881 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 384 M0110882 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 385 M0110883 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 386 M0110884 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 387 M0110885 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 388 M0110886 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 389 M0110887 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 390 M0110888 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 391 M0110889 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 392 M0110890 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 393 M0110891 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 394 M0110892 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 395 M0110893 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 396 M0110894 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 397 M0110895 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 398 M0110896 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 399 M0110897 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 400 M0110898 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 401 M0110899 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 402 M0110900 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 403 M0110901 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 404 M0110902 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 405 M0110903 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 406 M0110904 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 407 M0110905 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 408 M0110906 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 409 M0110907 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 410 M0110908 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 411 M0110909 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 412 M0110910 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 413 M0110911 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 414 M0110912 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 415 M0110913 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 416 M0110914 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 417 M0110915 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 418 M0110916 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 419 M0110917 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 420 M0110918 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 421 M0110919 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 422 M0110920 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 423 M0110921 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 424 M0110922 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 425 M0110923 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 426 M0110924 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 427 M0110925 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 428 M0110926 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 429 M0110927 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 430 M0110928 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 431 M0110929 NZ_CP121525.1 KAOOAMGK_00173 NZ_CP121525.1__KAOOAMGK_00173 NZ_CP121525.1 C1 KAOOAMGK_00173 ARO:3003902 Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria. antibiotic-resistant UhpT 96.1 0 1 459 1.0 1 phosphonic acid antibiotic antibiotic target alteration 432 M0110965 NZ_CP121525.1 KAOOAMGK_00025 NZ_CP121525.1__KAOOAMGK_00025 NZ_CP121525.1 C1 KAOOAMGK_00025 ARO:3000178 tet(K) TetK is a tetracycline efflux protein found in both Gram-negative (Haemophilus and Gallibacterium) and Gram-positive (many species, including mycobacteria) bacteria. major facilitator superfamily (MFS) antibiotic efflux pump 100 5.90999999977171e-315 1 459 1.0 1 tetracycline antibiotic antibiotic efflux 433 M0110966 NZ_CP121525.1 KAOOAMGK_00025 NZ_CP121525.1__KAOOAMGK_00025 NZ_CP121525.1 C1 KAOOAMGK_00025 ARO:3000178 tet(K) TetK is a tetracycline efflux protein found in both Gram-negative (Haemophilus and Gallibacterium) and Gram-positive (many species, including mycobacteria) bacteria. major facilitator superfamily (MFS) antibiotic efflux pump 100 5.90999999977171e-315 1 459 1.0 1 tetracycline antibiotic antibiotic efflux 434 M0110967 NZ_CP121525.1 KAOOAMGK_00025 NZ_CP121525.1__KAOOAMGK_00025 NZ_CP121525.1 C1 KAOOAMGK_00025 ARO:3000178 tet(K) TetK is a tetracycline efflux protein found in both Gram-negative (Haemophilus and Gallibacterium) and Gram-positive (many species, including mycobacteria) bacteria. major facilitator superfamily (MFS) antibiotic efflux pump 100 5.90999999977171e-315 1 459 1.0 1 tetracycline antibiotic antibiotic efflux 435 M0110968 NZ_CP121525.1 KAOOAMGK_00025 NZ_CP121525.1__KAOOAMGK_00025 NZ_CP121525.1 C1 KAOOAMGK_00025 ARO:3000178 tet(K) TetK is a tetracycline efflux protein found in both Gram-negative (Haemophilus and Gallibacterium) and Gram-positive (many species, including mycobacteria) bacteria. major facilitator superfamily (MFS) antibiotic efflux pump 100 5.90999999977171e-315 1 459 1.0 1 tetracycline antibiotic antibiotic efflux 436 M0111158 NZ_CP121525.1 KAOOAMGK_00025 NZ_CP121525.1__KAOOAMGK_00025 NZ_CP121525.1 C1 KAOOAMGK_00025 ARO:3000178 tet(K) TetK is a tetracycline efflux protein found in both Gram-negative (Haemophilus and Gallibacterium) and Gram-positive (many species, including mycobacteria) bacteria. major facilitator superfamily (MFS) antibiotic efflux pump 100 5.90999999977171e-315 1 459 1.0 1 tetracycline antibiotic antibiotic efflux 437 M0111945 NZ_CP121525.1 KAOOAMGK_00025 NZ_CP121525.1__KAOOAMGK_00025 NZ_CP121525.1 C1 KAOOAMGK_00025 ARO:3000178 tet(K) TetK is a tetracycline efflux protein found in both Gram-negative (Haemophilus and Gallibacterium) and Gram-positive (many species, including mycobacteria) bacteria. major facilitator superfamily (MFS) antibiotic efflux pump 100 5.90999999977171e-315 1 459 1.0 1 tetracycline antibiotic antibiotic efflux 438 M0111946 NZ_CP121525.1 KAOOAMGK_00025 NZ_CP121525.1__KAOOAMGK_00025 NZ_CP121525.1 C1 KAOOAMGK_00025 ARO:3000178 tet(K) TetK is a tetracycline efflux protein found in both Gram-negative (Haemophilus and Gallibacterium) and Gram-positive (many species, including mycobacteria) bacteria. major facilitator superfamily (MFS) antibiotic efflux pump 100 5.90999999977171e-315 1 459 1.0 1 tetracycline antibiotic antibiotic efflux 439 M0112287 NZ_CP121525.1 KAOOAMGK_00025 NZ_CP121525.1__KAOOAMGK_00025 NZ_CP121525.1 C1 KAOOAMGK_00025 ARO:3000178 tet(K) TetK is a tetracycline efflux protein found in both Gram-negative (Haemophilus and Gallibacterium) and Gram-positive (many species, including mycobacteria) bacteria. major facilitator superfamily (MFS) antibiotic efflux pump 100 5.90999999977171e-315 1 459 1.0 1 tetracycline antibiotic antibiotic efflux 440 M0112585 NZ_CP125670.1 HPKNOADA_00062 NZ_CP125670.1__HPKNOADA_00062 NZ_CP125670.1 C1166 HPKNOADA_00062 ARO:3000504 golS GolS is a regulator activated by the presence of golD, and promotes the expression of the MdsABC efflux pump. resistance-nodulation-cell division (RND) antibiotic efflux pump 70.5 2.2e-61 1 129 0.8486842105263158 0.837662337662338 monobactam antibiotic efflux 441 M0112860 NZ_CP130568.1 APAGFDOH_00032 NZ_CP130568.1__APAGFDOH_00032 NZ_CP130568.1 C1193 APAGFDOH_00032 ARO:3000251 msrA MsrA is an ABC-F subfamily ribosomal protection protein expressed in Staphylococcus species which confers resistance to erythromycin and streptogramin B antibiotics through antibiotic target protection mechanisms. It is associated with plasmid DNA. msr-type ABC-F protein 95.7 2.0997789948253e-320 1 488 1.0 1 macrolide antibiotic antibiotic target protection 442 M0112862 NZ_CP131786.1 DEOCPECH_00283 NZ_CP131786.1__DEOCPECH_00283 NZ_CP131786.1 C1195 DEOCPECH_00283 ARO:3002660 APH(6)-Id APH(6)-Id is an aminoglycoside phosphotransferase encoded by plasmids, integrative conjugative elements and chromosomal genomic islands in K. pneumoniae, Salmonella spp., E. coli, Shigella flexneri, Providencia alcalifaciens, Pseudomonas spp., V. cholerae, Edwardsiella tarda, Pasteurella multocida and Aeromonas bestiarum. APH(6) 99.6 1.07e-205 1 278 1.0 1 aminoglycoside antibiotic antibiotic inactivation 443 M0112863 NZ_CP131786.1 DEOCPECH_00284 NZ_CP131786.1__DEOCPECH_00284 NZ_CP131786.1 C1195 DEOCPECH_00284 ARO:3002639 APH(3'')-Ib APH(3'')-Ib is an aminoglycoside phosphotransferase encoded by plasmids, transposons, integrative conjugative elements and chromosomes in Enterobacteriaceae and Pseudomonas spp. APH(3'') 100 3.6e-203 1 267 1.0 1 aminoglycoside antibiotic antibiotic inactivation 444 M0112968 NZ_CP133000.1 BPNGJCOO_00025 NZ_CP133000.1__BPNGJCOO_00025 NZ_CP133000.1 C1201 BPNGJCOO_00025 ARO:3000251 msrA MsrA is an ABC-F subfamily ribosomal protection protein expressed in Staphylococcus species which confers resistance to erythromycin and streptogramin B antibiotics through antibiotic target protection mechanisms. It is associated with plasmid DNA. msr-type ABC-F protein 95.7 2.0997789948253e-320 1 488 1.0 1 macrolide antibiotic antibiotic target protection 445 M0115361 NZ_CP146093.1 PIJCFOGG_00279 NZ_CP146093.1__PIJCFOGG_00279 NZ_CP146093.1 C1268 PIJCFOGG_00279 ARO:3000790 mdsB MdsB is the inner membrane transporter of the multidrug and metal efflux complex MdsABC. mdsB corresponds to 1 locus in Pseudomonas aeruginosa PAO1 (gene name: mexQ) and 2 loci in Pseudomonas aeruginosa LESB58. resistance-nodulation-cell division (RND) antibiotic efflux pump 80 0 1 1047 0.9896030245746692 0.992417061611374 monobactam antibiotic efflux 446 M0115362 NZ_CP146093.1 PIJCFOGG_00279 NZ_CP146093.1__PIJCFOGG_00279 NZ_CP146093.1 C1268 PIJCFOGG_00279 ARO:3000790 mdsB MdsB is the inner membrane transporter of the multidrug and metal efflux complex MdsABC. mdsB corresponds to 1 locus in Pseudomonas aeruginosa PAO1 (gene name: mexQ) and 2 loci in Pseudomonas aeruginosa LESB58. resistance-nodulation-cell division (RND) antibiotic efflux pump 80 0 1 1047 0.9896030245746692 0.992417061611374 monobactam antibiotic efflux 447 M0115363 NZ_CP146093.1 PIJCFOGG_00279 NZ_CP146093.1__PIJCFOGG_00279 NZ_CP146093.1 C1268 PIJCFOGG_00279 ARO:3000790 mdsB MdsB is the inner membrane transporter of the multidrug and metal efflux complex MdsABC. mdsB corresponds to 1 locus in Pseudomonas aeruginosa PAO1 (gene name: mexQ) and 2 loci in Pseudomonas aeruginosa LESB58. resistance-nodulation-cell division (RND) antibiotic efflux pump 80 0 1 1047 0.9896030245746692 0.992417061611374 monobactam antibiotic efflux 448 M0115364 NZ_CP146093.1 PIJCFOGG_00279 NZ_CP146093.1__PIJCFOGG_00279 NZ_CP146093.1 C1268 PIJCFOGG_00279 ARO:3000790 mdsB MdsB is the inner membrane transporter of the multidrug and metal efflux complex MdsABC. mdsB corresponds to 1 locus in Pseudomonas aeruginosa PAO1 (gene name: mexQ) and 2 loci in Pseudomonas aeruginosa LESB58. resistance-nodulation-cell division (RND) antibiotic efflux pump 80 0 1 1047 0.9896030245746692 0.992417061611374 monobactam antibiotic efflux 449 M0115365 NZ_CP146093.1 PIJCFOGG_00279 NZ_CP146093.1__PIJCFOGG_00279 NZ_CP146093.1 C1268 PIJCFOGG_00279 ARO:3000790 mdsB MdsB is the inner membrane transporter of the multidrug and metal efflux complex MdsABC. mdsB corresponds to 1 locus in Pseudomonas aeruginosa PAO1 (gene name: mexQ) and 2 loci in Pseudomonas aeruginosa LESB58. resistance-nodulation-cell division (RND) antibiotic efflux pump 80 0 1 1047 0.9896030245746692 0.992417061611374 monobactam antibiotic efflux 450 M0115366 NZ_CP146093.1 PIJCFOGG_00279 NZ_CP146093.1__PIJCFOGG_00279 NZ_CP146093.1 C1268 PIJCFOGG_00279 ARO:3000790 mdsB MdsB is the inner membrane transporter of the multidrug and metal efflux complex MdsABC. mdsB corresponds to 1 locus in Pseudomonas aeruginosa PAO1 (gene name: mexQ) and 2 loci in Pseudomonas aeruginosa LESB58. resistance-nodulation-cell division (RND) antibiotic efflux pump 80 0 1 1047 0.9896030245746692 0.992417061611374 monobactam antibiotic efflux 451 M0115498 NZ_CP146093.1 PIJCFOGG_00279 NZ_CP146093.1__PIJCFOGG_00279 NZ_CP146093.1 C1268 PIJCFOGG_00279 ARO:3000790 mdsB MdsB is the inner membrane transporter of the multidrug and metal efflux complex MdsABC. mdsB corresponds to 1 locus in Pseudomonas aeruginosa PAO1 (gene name: mexQ) and 2 loci in Pseudomonas aeruginosa LESB58. resistance-nodulation-cell division (RND) antibiotic efflux pump 80 0 1 1047 0.9896030245746692 0.992417061611374 monobactam antibiotic efflux 452 M0115499 NZ_CP146093.1 PIJCFOGG_00279 NZ_CP146093.1__PIJCFOGG_00279 NZ_CP146093.1 C1268 PIJCFOGG_00279 ARO:3000790 mdsB MdsB is the inner membrane transporter of the multidrug and metal efflux complex MdsABC. mdsB corresponds to 1 locus in Pseudomonas aeruginosa PAO1 (gene name: mexQ) and 2 loci in Pseudomonas aeruginosa LESB58. resistance-nodulation-cell division (RND) antibiotic efflux pump 80 0 1 1047 0.9896030245746692 0.992417061611374 monobactam antibiotic efflux 453 M0115500 NZ_CP146093.1 PIJCFOGG_00279 NZ_CP146093.1__PIJCFOGG_00279 NZ_CP146093.1 C1268 PIJCFOGG_00279 ARO:3000790 mdsB MdsB is the inner membrane transporter of the multidrug and metal efflux complex MdsABC. mdsB corresponds to 1 locus in Pseudomonas aeruginosa PAO1 (gene name: mexQ) and 2 loci in Pseudomonas aeruginosa LESB58. resistance-nodulation-cell division (RND) antibiotic efflux pump 80 0 1 1047 0.9896030245746692 0.992417061611374 monobactam antibiotic efflux 454 M0115501 NZ_CP146093.1 PIJCFOGG_00279 NZ_CP146093.1__PIJCFOGG_00279 NZ_CP146093.1 C1268 PIJCFOGG_00279 ARO:3000790 mdsB MdsB is the inner membrane transporter of the multidrug and metal efflux complex MdsABC. mdsB corresponds to 1 locus in Pseudomonas aeruginosa PAO1 (gene name: mexQ) and 2 loci in Pseudomonas aeruginosa LESB58. resistance-nodulation-cell division (RND) antibiotic efflux pump 80 0 1 1047 0.9896030245746692 0.992417061611374 monobactam antibiotic efflux 455 M0115535 NZ_CP146093.1 PIJCFOGG_00279 NZ_CP146093.1__PIJCFOGG_00279 NZ_CP146093.1 C1268 PIJCFOGG_00279 ARO:3000790 mdsB MdsB is the inner membrane transporter of the multidrug and metal efflux complex MdsABC. mdsB corresponds to 1 locus in Pseudomonas aeruginosa PAO1 (gene name: mexQ) and 2 loci in Pseudomonas aeruginosa LESB58. resistance-nodulation-cell division (RND) antibiotic efflux pump 80 0 1 1047 0.9896030245746692 0.992417061611374 monobactam antibiotic efflux 456 M0115536 NZ_CP146093.1 PIJCFOGG_00279 NZ_CP146093.1__PIJCFOGG_00279 NZ_CP146093.1 C1268 PIJCFOGG_00279 ARO:3000790 mdsB MdsB is the inner membrane transporter of the multidrug and metal efflux complex MdsABC. mdsB corresponds to 1 locus in Pseudomonas aeruginosa PAO1 (gene name: mexQ) and 2 loci in Pseudomonas aeruginosa LESB58. resistance-nodulation-cell division (RND) antibiotic efflux pump 80 0 1 1047 0.9896030245746692 0.992417061611374 monobactam antibiotic efflux 457 M0115537 NZ_CP146093.1 PIJCFOGG_00279 NZ_CP146093.1__PIJCFOGG_00279 NZ_CP146093.1 C1268 PIJCFOGG_00279 ARO:3000790 mdsB MdsB is the inner membrane transporter of the multidrug and metal efflux complex MdsABC. mdsB corresponds to 1 locus in Pseudomonas aeruginosa PAO1 (gene name: mexQ) and 2 loci in Pseudomonas aeruginosa LESB58. resistance-nodulation-cell division (RND) antibiotic efflux pump 80 0 1 1047 0.9896030245746692 0.992417061611374 monobactam antibiotic efflux 458 M0115538 NZ_CP146093.1 PIJCFOGG_00279 NZ_CP146093.1__PIJCFOGG_00279 NZ_CP146093.1 C1268 PIJCFOGG_00279 ARO:3000790 mdsB MdsB is the inner membrane transporter of the multidrug and metal efflux complex MdsABC. mdsB corresponds to 1 locus in Pseudomonas aeruginosa PAO1 (gene name: mexQ) and 2 loci in Pseudomonas aeruginosa LESB58. resistance-nodulation-cell division (RND) antibiotic efflux pump 80 0 1 1047 0.9896030245746692 0.992417061611374 monobactam antibiotic efflux 459 M0115539 NZ_CP146093.1 PIJCFOGG_00279 NZ_CP146093.1__PIJCFOGG_00279 NZ_CP146093.1 C1268 PIJCFOGG_00279 ARO:3000790 mdsB MdsB is the inner membrane transporter of the multidrug and metal efflux complex MdsABC. mdsB corresponds to 1 locus in Pseudomonas aeruginosa PAO1 (gene name: mexQ) and 2 loci in Pseudomonas aeruginosa LESB58. resistance-nodulation-cell division (RND) antibiotic efflux pump 80 0 1 1047 0.9896030245746692 0.992417061611374 monobactam antibiotic efflux 460 M0115540 NZ_CP146093.1 PIJCFOGG_00279 NZ_CP146093.1__PIJCFOGG_00279 NZ_CP146093.1 C1268 PIJCFOGG_00279 ARO:3000790 mdsB MdsB is the inner membrane transporter of the multidrug and metal efflux complex MdsABC. mdsB corresponds to 1 locus in Pseudomonas aeruginosa PAO1 (gene name: mexQ) and 2 loci in Pseudomonas aeruginosa LESB58. resistance-nodulation-cell division (RND) antibiotic efflux pump 80 0 1 1047 0.9896030245746692 0.992417061611374 monobactam antibiotic efflux 461 M0115541 NZ_CP146093.1 PIJCFOGG_00279 NZ_CP146093.1__PIJCFOGG_00279 NZ_CP146093.1 C1268 PIJCFOGG_00279 ARO:3000790 mdsB MdsB is the inner membrane transporter of the multidrug and metal efflux complex MdsABC. mdsB corresponds to 1 locus in Pseudomonas aeruginosa PAO1 (gene name: mexQ) and 2 loci in Pseudomonas aeruginosa LESB58. resistance-nodulation-cell division (RND) antibiotic efflux pump 80 0 1 1047 0.9896030245746692 0.992417061611374 monobactam antibiotic efflux 462 M0115542 NZ_CP146093.1 PIJCFOGG_00279 NZ_CP146093.1__PIJCFOGG_00279 NZ_CP146093.1 C1268 PIJCFOGG_00279 ARO:3000790 mdsB MdsB is the inner membrane transporter of the multidrug and metal efflux complex MdsABC. mdsB corresponds to 1 locus in Pseudomonas aeruginosa PAO1 (gene name: mexQ) and 2 loci in Pseudomonas aeruginosa LESB58. resistance-nodulation-cell division (RND) antibiotic efflux pump 80 0 1 1047 0.9896030245746692 0.992417061611374 monobactam antibiotic efflux 463 M0115543 NZ_CP146093.1 PIJCFOGG_00279 NZ_CP146093.1__PIJCFOGG_00279 NZ_CP146093.1 C1268 PIJCFOGG_00279 ARO:3000790 mdsB MdsB is the inner membrane transporter of the multidrug and metal efflux complex MdsABC. mdsB corresponds to 1 locus in Pseudomonas aeruginosa PAO1 (gene name: mexQ) and 2 loci in Pseudomonas aeruginosa LESB58. resistance-nodulation-cell division (RND) antibiotic efflux pump 80 0 1 1047 0.9896030245746692 0.992417061611374 monobactam antibiotic efflux 464 M0115544 NZ_CP146093.1 PIJCFOGG_00279 NZ_CP146093.1__PIJCFOGG_00279 NZ_CP146093.1 C1268 PIJCFOGG_00279 ARO:3000790 mdsB MdsB is the inner membrane transporter of the multidrug and metal efflux complex MdsABC. mdsB corresponds to 1 locus in Pseudomonas aeruginosa PAO1 (gene name: mexQ) and 2 loci in Pseudomonas aeruginosa LESB58. resistance-nodulation-cell division (RND) antibiotic efflux pump 80 0 1 1047 0.9896030245746692 0.992417061611374 monobactam antibiotic efflux 465 M0115545 NZ_CP146093.1 PIJCFOGG_00279 NZ_CP146093.1__PIJCFOGG_00279 NZ_CP146093.1 C1268 PIJCFOGG_00279 ARO:3000790 mdsB MdsB is the inner membrane transporter of the multidrug and metal efflux complex MdsABC. mdsB corresponds to 1 locus in Pseudomonas aeruginosa PAO1 (gene name: mexQ) and 2 loci in Pseudomonas aeruginosa LESB58. resistance-nodulation-cell division (RND) antibiotic efflux pump 80 0 1 1047 0.9896030245746692 0.992417061611374 monobactam antibiotic efflux 466 M0115546 NZ_CP146093.1 PIJCFOGG_00279 NZ_CP146093.1__PIJCFOGG_00279 NZ_CP146093.1 C1268 PIJCFOGG_00279 ARO:3000790 mdsB MdsB is the inner membrane transporter of the multidrug and metal efflux complex MdsABC. mdsB corresponds to 1 locus in Pseudomonas aeruginosa PAO1 (gene name: mexQ) and 2 loci in Pseudomonas aeruginosa LESB58. resistance-nodulation-cell division (RND) antibiotic efflux pump 80 0 1 1047 0.9896030245746692 0.992417061611374 monobactam antibiotic efflux 467 M0115547 NZ_CP146093.1 PIJCFOGG_00279 NZ_CP146093.1__PIJCFOGG_00279 NZ_CP146093.1 C1268 PIJCFOGG_00279 ARO:3000790 mdsB MdsB is the inner membrane transporter of the multidrug and metal efflux complex MdsABC. mdsB corresponds to 1 locus in Pseudomonas aeruginosa PAO1 (gene name: mexQ) and 2 loci in Pseudomonas aeruginosa LESB58. resistance-nodulation-cell division (RND) antibiotic efflux pump 80 0 1 1047 0.9896030245746692 0.992417061611374 monobactam antibiotic efflux 468 M0115586 NZ_CP146093.1 PIJCFOGG_00279 NZ_CP146093.1__PIJCFOGG_00279 NZ_CP146093.1 C1268 PIJCFOGG_00279 ARO:3000790 mdsB MdsB is the inner membrane transporter of the multidrug and metal efflux complex MdsABC. mdsB corresponds to 1 locus in Pseudomonas aeruginosa PAO1 (gene name: mexQ) and 2 loci in Pseudomonas aeruginosa LESB58. resistance-nodulation-cell division (RND) antibiotic efflux pump 80 0 1 1047 0.9896030245746692 0.992417061611374 monobactam antibiotic efflux 469 M0115587 NZ_CP146093.1 PIJCFOGG_00279 NZ_CP146093.1__PIJCFOGG_00279 NZ_CP146093.1 C1268 PIJCFOGG_00279 ARO:3000790 mdsB MdsB is the inner membrane transporter of the multidrug and metal efflux complex MdsABC. mdsB corresponds to 1 locus in Pseudomonas aeruginosa PAO1 (gene name: mexQ) and 2 loci in Pseudomonas aeruginosa LESB58. resistance-nodulation-cell division (RND) antibiotic efflux pump 80 0 1 1047 0.9896030245746692 0.992417061611374 monobactam antibiotic efflux 470 M0115725 NZ_CP146094.1 LHPNBJEB_00403 NZ_CP146094.1__LHPNBJEB_00403 NZ_CP146094.1 C1269 LHPNBJEB_00403 ARO:3000504 golS GolS is a regulator activated by the presence of golD, and promotes the expression of the MdsABC efflux pump. resistance-nodulation-cell division (RND) antibiotic efflux pump 81.1 9.49e-81 1 148 0.9308176100628931 0.961038961038961 monobactam antibiotic efflux 471 M0115726 NZ_CP146094.1 LHPNBJEB_00403 NZ_CP146094.1__LHPNBJEB_00403 NZ_CP146094.1 C1269 LHPNBJEB_00403 ARO:3000504 golS GolS is a regulator activated by the presence of golD, and promotes the expression of the MdsABC efflux pump. resistance-nodulation-cell division (RND) antibiotic efflux pump 81.1 9.49e-81 1 148 0.9308176100628931 0.961038961038961 monobactam antibiotic efflux 472 M0115727 NZ_CP146094.1 LHPNBJEB_00403 NZ_CP146094.1__LHPNBJEB_00403 NZ_CP146094.1 C1269 LHPNBJEB_00403 ARO:3000504 golS GolS is a regulator activated by the presence of golD, and promotes the expression of the MdsABC efflux pump. resistance-nodulation-cell division (RND) antibiotic efflux pump 81.1 9.49e-81 1 148 0.9308176100628931 0.961038961038961 monobactam antibiotic efflux 473 M0115849 NZ_CP146094.1 LHPNBJEB_00403 NZ_CP146094.1__LHPNBJEB_00403 NZ_CP146094.1 C1269 LHPNBJEB_00403 ARO:3000504 golS GolS is a regulator activated by the presence of golD, and promotes the expression of the MdsABC efflux pump. resistance-nodulation-cell division (RND) antibiotic efflux pump 81.1 9.49e-81 1 148 0.9308176100628931 0.961038961038961 monobactam antibiotic efflux 474 M0115850 NZ_CP146094.1 LHPNBJEB_00403 NZ_CP146094.1__LHPNBJEB_00403 NZ_CP146094.1 C1269 LHPNBJEB_00403 ARO:3000504 golS GolS is a regulator activated by the presence of golD, and promotes the expression of the MdsABC efflux pump. resistance-nodulation-cell division (RND) antibiotic efflux pump 81.1 9.49e-81 1 148 0.9308176100628931 0.961038961038961 monobactam antibiotic efflux 475 M0115851 NZ_CP146094.1 LHPNBJEB_00403 NZ_CP146094.1__LHPNBJEB_00403 NZ_CP146094.1 C1269 LHPNBJEB_00403 ARO:3000504 golS GolS is a regulator activated by the presence of golD, and promotes the expression of the MdsABC efflux pump. resistance-nodulation-cell division (RND) antibiotic efflux pump 81.1 9.49e-81 1 148 0.9308176100628931 0.961038961038961 monobactam antibiotic efflux 476 M0115852 NZ_CP146094.1 LHPNBJEB_00403 NZ_CP146094.1__LHPNBJEB_00403 NZ_CP146094.1 C1269 LHPNBJEB_00403 ARO:3000504 golS GolS is a regulator activated by the presence of golD, and promotes the expression of the MdsABC efflux pump. resistance-nodulation-cell division (RND) antibiotic efflux pump 81.1 9.49e-81 1 148 0.9308176100628931 0.961038961038961 monobactam antibiotic efflux 477 M0115853 NZ_CP146094.1 LHPNBJEB_00403 NZ_CP146094.1__LHPNBJEB_00403 NZ_CP146094.1 C1269 LHPNBJEB_00403 ARO:3000504 golS GolS is a regulator activated by the presence of golD, and promotes the expression of the MdsABC efflux pump. resistance-nodulation-cell division (RND) antibiotic efflux pump 81.1 9.49e-81 1 148 0.9308176100628931 0.961038961038961 monobactam antibiotic efflux 478 M0115854 NZ_CP146094.1 LHPNBJEB_00403 NZ_CP146094.1__LHPNBJEB_00403 NZ_CP146094.1 C1269 LHPNBJEB_00403 ARO:3000504 golS GolS is a regulator activated by the presence of golD, and promotes the expression of the MdsABC efflux pump. resistance-nodulation-cell division (RND) antibiotic efflux pump 81.1 9.49e-81 1 148 0.9308176100628931 0.961038961038961 monobactam antibiotic efflux 479 M0115855 NZ_CP146094.1 LHPNBJEB_00403 NZ_CP146094.1__LHPNBJEB_00403 NZ_CP146094.1 C1269 LHPNBJEB_00403 ARO:3000504 golS GolS is a regulator activated by the presence of golD, and promotes the expression of the MdsABC efflux pump. resistance-nodulation-cell division (RND) antibiotic efflux pump 81.1 9.49e-81 1 148 0.9308176100628931 0.961038961038961 monobactam antibiotic efflux 480 M0115856 NZ_CP146094.1 LHPNBJEB_00403 NZ_CP146094.1__LHPNBJEB_00403 NZ_CP146094.1 C1269 LHPNBJEB_00403 ARO:3000504 golS GolS is a regulator activated by the presence of golD, and promotes the expression of the MdsABC efflux pump. resistance-nodulation-cell division (RND) antibiotic efflux pump 81.1 9.49e-81 1 148 0.9308176100628931 0.961038961038961 monobactam antibiotic efflux 481 M0115857 NZ_CP146094.1 LHPNBJEB_00403 NZ_CP146094.1__LHPNBJEB_00403 NZ_CP146094.1 C1269 LHPNBJEB_00403 ARO:3000504 golS GolS is a regulator activated by the presence of golD, and promotes the expression of the MdsABC efflux pump. resistance-nodulation-cell division (RND) antibiotic efflux pump 81.1 9.49e-81 1 148 0.9308176100628931 0.961038961038961 monobactam antibiotic efflux 482 M0115858 NZ_CP146094.1 LHPNBJEB_00403 NZ_CP146094.1__LHPNBJEB_00403 NZ_CP146094.1 C1269 LHPNBJEB_00403 ARO:3000504 golS GolS is a regulator activated by the presence of golD, and promotes the expression of the MdsABC efflux pump. resistance-nodulation-cell division (RND) antibiotic efflux pump 81.1 9.49e-81 1 148 0.9308176100628931 0.961038961038961 monobactam antibiotic efflux 483 M0115859 NZ_CP146094.1 LHPNBJEB_00403 NZ_CP146094.1__LHPNBJEB_00403 NZ_CP146094.1 C1269 LHPNBJEB_00403 ARO:3000504 golS GolS is a regulator activated by the presence of golD, and promotes the expression of the MdsABC efflux pump. resistance-nodulation-cell division (RND) antibiotic efflux pump 81.1 9.49e-81 1 148 0.9308176100628931 0.961038961038961 monobactam antibiotic efflux 484 M0115860 NZ_CP146094.1 LHPNBJEB_00403 NZ_CP146094.1__LHPNBJEB_00403 NZ_CP146094.1 C1269 LHPNBJEB_00403 ARO:3000504 golS GolS is a regulator activated by the presence of golD, and promotes the expression of the MdsABC efflux pump. resistance-nodulation-cell division (RND) antibiotic efflux pump 81.1 9.49e-81 1 148 0.9308176100628931 0.961038961038961 monobactam antibiotic efflux 485 M0115861 NZ_CP146094.1 LHPNBJEB_00403 NZ_CP146094.1__LHPNBJEB_00403 NZ_CP146094.1 C1269 LHPNBJEB_00403 ARO:3000504 golS GolS is a regulator activated by the presence of golD, and promotes the expression of the MdsABC efflux pump. resistance-nodulation-cell division (RND) antibiotic efflux pump 81.1 9.49e-81 1 148 0.9308176100628931 0.961038961038961 monobactam antibiotic efflux 486 M0115862 NZ_CP146094.1 LHPNBJEB_00403 NZ_CP146094.1__LHPNBJEB_00403 NZ_CP146094.1 C1269 LHPNBJEB_00403 ARO:3000504 golS GolS is a regulator activated by the presence of golD, and promotes the expression of the MdsABC efflux pump. resistance-nodulation-cell division (RND) antibiotic efflux pump 81.1 9.49e-81 1 148 0.9308176100628931 0.961038961038961 monobactam antibiotic efflux 487 M0115863 NZ_CP146094.1 LHPNBJEB_00403 NZ_CP146094.1__LHPNBJEB_00403 NZ_CP146094.1 C1269 LHPNBJEB_00403 ARO:3000504 golS GolS is a regulator activated by the presence of golD, and promotes the expression of the MdsABC efflux pump. resistance-nodulation-cell division (RND) antibiotic efflux pump 81.1 9.49e-81 1 148 0.9308176100628931 0.961038961038961 monobactam antibiotic efflux 488 M0115864 NZ_CP146094.1 LHPNBJEB_00403 NZ_CP146094.1__LHPNBJEB_00403 NZ_CP146094.1 C1269 LHPNBJEB_00403 ARO:3000504 golS GolS is a regulator activated by the presence of golD, and promotes the expression of the MdsABC efflux pump. resistance-nodulation-cell division (RND) antibiotic efflux pump 81.1 9.49e-81 1 148 0.9308176100628931 0.961038961038961 monobactam antibiotic efflux 489 M0115865 NZ_CP146094.1 LHPNBJEB_00403 NZ_CP146094.1__LHPNBJEB_00403 NZ_CP146094.1 C1269 LHPNBJEB_00403 ARO:3000504 golS GolS is a regulator activated by the presence of golD, and promotes the expression of the MdsABC efflux pump. resistance-nodulation-cell division (RND) antibiotic efflux pump 81.1 9.49e-81 1 148 0.9308176100628931 0.961038961038961 monobactam antibiotic efflux 490 M0115956 NZ_CP151149.1 LJHPLMKJ_00004 NZ_CP151149.1__LJHPLMKJ_00004 NZ_CP151149.1 C1306 LJHPLMKJ_00004 ARO:3003046 qacA qacA is a subunit of the qac multidrug efflux pump. major facilitator superfamily (MFS) antibiotic efflux pump 99.8 0 1 514 1.0 1 fluoroquinolone antibiotic antibiotic efflux 491 M0115957 NZ_CP151149.1 LJHPLMKJ_00004 NZ_CP151149.1__LJHPLMKJ_00004 NZ_CP151149.1 C1306 LJHPLMKJ_00004 ARO:3003046 qacA qacA is a subunit of the qac multidrug efflux pump. major facilitator superfamily (MFS) antibiotic efflux pump 99.8 0 1 514 1.0 1 fluoroquinolone antibiotic antibiotic efflux 492 M0115958 NZ_CP151149.1 LJHPLMKJ_00004 NZ_CP151149.1__LJHPLMKJ_00004 NZ_CP151149.1 C1306 LJHPLMKJ_00004 ARO:3003046 qacA qacA is a subunit of the qac multidrug efflux pump. major facilitator superfamily (MFS) antibiotic efflux pump 99.8 0 1 514 1.0 1 fluoroquinolone antibiotic antibiotic efflux 493 M0115959 NZ_CP151149.1 LJHPLMKJ_00004 NZ_CP151149.1__LJHPLMKJ_00004 NZ_CP151149.1 C1306 LJHPLMKJ_00004 ARO:3003046 qacA qacA is a subunit of the qac multidrug efflux pump. major facilitator superfamily (MFS) antibiotic efflux pump 99.8 0 1 514 1.0 1 fluoroquinolone antibiotic antibiotic efflux 494 M0115969 NZ_CP155542.1 PDPMKEMA_00032 NZ_CP155542.1__PDPMKEMA_00032 NZ_CP155542.1 C1316 PDPMKEMA_00032 ARO:3000251 msrA MsrA is an ABC-F subfamily ribosomal protection protein expressed in Staphylococcus species which confers resistance to erythromycin and streptogramin B antibiotics through antibiotic target protection mechanisms. It is associated with plasmid DNA. msr-type ABC-F protein 95.7 2.0997789948253e-320 1 488 1.0 1 macrolide antibiotic antibiotic target protection 495 M0115970 NZ_CP155542.1 PDPMKEMA_00020 NZ_CP155542.1__PDPMKEMA_00020 NZ_CP155542.1 C1316 PDPMKEMA_00020 ARO:3003046 qacA qacA is a subunit of the qac multidrug efflux pump. major facilitator superfamily (MFS) antibiotic efflux pump 99.8 0 1 514 1.0 1 fluoroquinolone antibiotic antibiotic efflux 496 M0115977 NZ_CP155542.1 PDPMKEMA_00032 NZ_CP155542.1__PDPMKEMA_00032 NZ_CP155542.1 C1316 PDPMKEMA_00032 ARO:3000251 msrA MsrA is an ABC-F subfamily ribosomal protection protein expressed in Staphylococcus species which confers resistance to erythromycin and streptogramin B antibiotics through antibiotic target protection mechanisms. It is associated with plasmid DNA. msr-type ABC-F protein 95.7 2.0997789948253e-320 1 488 1.0 1 macrolide antibiotic antibiotic target protection 497 M0115978 NZ_CP155542.1 PDPMKEMA_00032 NZ_CP155542.1__PDPMKEMA_00032 NZ_CP155542.1 C1316 PDPMKEMA_00032 ARO:3000251 msrA MsrA is an ABC-F subfamily ribosomal protection protein expressed in Staphylococcus species which confers resistance to erythromycin and streptogramin B antibiotics through antibiotic target protection mechanisms. It is associated with plasmid DNA. msr-type ABC-F protein 95.7 2.0997789948253e-320 1 488 1.0 1 macrolide antibiotic antibiotic target protection 498 M0115989 NZ_CP155542.1 PDPMKEMA_00020 NZ_CP155542.1__PDPMKEMA_00020 NZ_CP155542.1 C1316 PDPMKEMA_00020 ARO:3003046 qacA qacA is a subunit of the qac multidrug efflux pump. major facilitator superfamily (MFS) antibiotic efflux pump 99.8 0 1 514 1.0 1 fluoroquinolone antibiotic antibiotic efflux 499 M0116459 NZ_KT780704.1 IICPEKDE_00049 NZ_KT780704.1__IICPEKDE_00049 NZ_KT780704.1 C1332 IICPEKDE_00049 ARO:3000617 mecA A foreign PBP2a acquired by lateral gene transfer that is able to perform peptidoglycan synthesis in the presence of beta-lactams. methicillin resistant PBP2 99.7 0 1 668 1.0 1 penicillin beta-lactam antibiotic target replacement 500 M0116460 NZ_KT780704.1 IICPEKDE_00048 NZ_KT780704.1__IICPEKDE_00048 NZ_KT780704.1 C1332 IICPEKDE_00048 ARO:3000215 mecR1 mecR1 is a transmembrane spanning and signal transducing protein which in response to interaction with beta-lactam antibiotics results in upregulation of the mecA/mecR1/mecI operon. methicillin resistant PBP2 100 0 1 585 1.0 1 penicillin beta-lactam antibiotic target replacement 501 M0116461 NZ_KT780704.1 IICPEKDE_00048 NZ_KT780704.1__IICPEKDE_00048 NZ_KT780704.1 C1332 IICPEKDE_00048 ARO:3000215 mecR1 mecR1 is a transmembrane spanning and signal transducing protein which in response to interaction with beta-lactam antibiotics results in upregulation of the mecA/mecR1/mecI operon. methicillin resistant PBP2 100 0 1 585 1.0 1 penicillin beta-lactam antibiotic target replacement 502 M0116462 NZ_KT780704.1 IICPEKDE_00048 NZ_KT780704.1__IICPEKDE_00048 NZ_KT780704.1 C1332 IICPEKDE_00048 ARO:3000215 mecR1 mecR1 is a transmembrane spanning and signal transducing protein which in response to interaction with beta-lactam antibiotics results in upregulation of the mecA/mecR1/mecI operon. methicillin resistant PBP2 100 0 1 585 1.0 1 penicillin beta-lactam antibiotic target replacement 503 M0116463 NZ_KT780704.1 IICPEKDE_00048 NZ_KT780704.1__IICPEKDE_00048 NZ_KT780704.1 C1332 IICPEKDE_00048 ARO:3000215 mecR1 mecR1 is a transmembrane spanning and signal transducing protein which in response to interaction with beta-lactam antibiotics results in upregulation of the mecA/mecR1/mecI operon. methicillin resistant PBP2 100 0 1 585 1.0 1 penicillin beta-lactam antibiotic target replacement 504 M0116464 NZ_KT780704.1 IICPEKDE_00048 NZ_KT780704.1__IICPEKDE_00048 NZ_KT780704.1 C1332 IICPEKDE_00048 ARO:3000215 mecR1 mecR1 is a transmembrane spanning and signal transducing protein which in response to interaction with beta-lactam antibiotics results in upregulation of the mecA/mecR1/mecI operon. methicillin resistant PBP2 100 0 1 585 1.0 1 penicillin beta-lactam antibiotic target replacement 505 M0116465 NZ_KT780704.1 IICPEKDE_00048 NZ_KT780704.1__IICPEKDE_00048 NZ_KT780704.1 C1332 IICPEKDE_00048 ARO:3000215 mecR1 mecR1 is a transmembrane spanning and signal transducing protein which in response to interaction with beta-lactam antibiotics results in upregulation of the mecA/mecR1/mecI operon. methicillin resistant PBP2 100 0 1 585 1.0 1 penicillin beta-lactam antibiotic target replacement 506 M0116466 NZ_KT780704.1 IICPEKDE_00048 NZ_KT780704.1__IICPEKDE_00048 NZ_KT780704.1 C1332 IICPEKDE_00048 ARO:3000215 mecR1 mecR1 is a transmembrane spanning and signal transducing protein which in response to interaction with beta-lactam antibiotics results in upregulation of the mecA/mecR1/mecI operon. methicillin resistant PBP2 100 0 1 585 1.0 1 penicillin beta-lactam antibiotic target replacement 507 M0116467 NZ_KT780704.1 IICPEKDE_00048 NZ_KT780704.1__IICPEKDE_00048 NZ_KT780704.1 C1332 IICPEKDE_00048 ARO:3000215 mecR1 mecR1 is a transmembrane spanning and signal transducing protein which in response to interaction with beta-lactam antibiotics results in upregulation of the mecA/mecR1/mecI operon. methicillin resistant PBP2 100 0 1 585 1.0 1 penicillin beta-lactam antibiotic target replacement 508 M0116468 NZ_KT780704.1 IICPEKDE_00048 NZ_KT780704.1__IICPEKDE_00048 NZ_KT780704.1 C1332 IICPEKDE_00048 ARO:3000215 mecR1 mecR1 is a transmembrane spanning and signal transducing protein which in response to interaction with beta-lactam antibiotics results in upregulation of the mecA/mecR1/mecI operon. methicillin resistant PBP2 100 0 1 585 1.0 1 penicillin beta-lactam antibiotic target replacement 509 M0116469 NZ_KT780704.1 IICPEKDE_00048 NZ_KT780704.1__IICPEKDE_00048 NZ_KT780704.1 C1332 IICPEKDE_00048 ARO:3000215 mecR1 mecR1 is a transmembrane spanning and signal transducing protein which in response to interaction with beta-lactam antibiotics results in upregulation of the mecA/mecR1/mecI operon. methicillin resistant PBP2 100 0 1 585 1.0 1 penicillin beta-lactam antibiotic target replacement 510 M0116470 NZ_KT780704.1 IICPEKDE_00048 NZ_KT780704.1__IICPEKDE_00048 NZ_KT780704.1 C1332 IICPEKDE_00048 ARO:3000215 mecR1 mecR1 is a transmembrane spanning and signal transducing protein which in response to interaction with beta-lactam antibiotics results in upregulation of the mecA/mecR1/mecI operon. methicillin resistant PBP2 100 0 1 585 1.0 1 penicillin beta-lactam antibiotic target replacement 511 M0116471 NZ_KT780704.1 IICPEKDE_00048 NZ_KT780704.1__IICPEKDE_00048 NZ_KT780704.1 C1332 IICPEKDE_00048 ARO:3000215 mecR1 mecR1 is a transmembrane spanning and signal transducing protein which in response to interaction with beta-lactam antibiotics results in upregulation of the mecA/mecR1/mecI operon. methicillin resistant PBP2 100 0 1 585 1.0 1 penicillin beta-lactam antibiotic target replacement 512 M0116498 NZ_KX712121.1 NMLJBKCF_00003 NZ_KX712121.1__NMLJBKCF_00003 NZ_KX712121.1 C1337 NMLJBKCF_00003 ARO:3002829 vgaA vgaA is an ABC-F subfamily protein expressed in staphylococci that confers resistance to streptogramin A antibiotics and related compounds. It is associated with plasmid DNA. vga-type ABC-F protein 97.1 0 1 519 1.0 0.994252873563218 lincosamide antibiotic antibiotic target protection 513 M0116499 NZ_KX712121.1 NMLJBKCF_00003 NZ_KX712121.1__NMLJBKCF_00003 NZ_KX712121.1 C1337 NMLJBKCF_00003 ARO:3002829 vgaA vgaA is an ABC-F subfamily protein expressed in staphylococci that confers resistance to streptogramin A antibiotics and related compounds. It is associated with plasmid DNA. vga-type ABC-F protein 97.1 0 1 519 1.0 0.994252873563218 lincosamide antibiotic antibiotic target protection 514 M0116500 NZ_KX712121.1 NMLJBKCF_00003 NZ_KX712121.1__NMLJBKCF_00003 NZ_KX712121.1 C1337 NMLJBKCF_00003 ARO:3002829 vgaA vgaA is an ABC-F subfamily protein expressed in staphylococci that confers resistance to streptogramin A antibiotics and related compounds. It is associated with plasmid DNA. vga-type ABC-F protein 97.1 0 1 519 1.0 0.994252873563218 lincosamide antibiotic antibiotic target protection 515 M0116501 NZ_KX712121.1 NMLJBKCF_00003 NZ_KX712121.1__NMLJBKCF_00003 NZ_KX712121.1 C1337 NMLJBKCF_00003 ARO:3002829 vgaA vgaA is an ABC-F subfamily protein expressed in staphylococci that confers resistance to streptogramin A antibiotics and related compounds. It is associated with plasmid DNA. vga-type ABC-F protein 97.1 0 1 519 1.0 0.994252873563218 lincosamide antibiotic antibiotic target protection 516 M0116677 NZ_MN961670.1 NAFPHALK_00246 NZ_MN961670.1__NAFPHALK_00246 NZ_MN961670.1 C1383 NAFPHALK_00246 ARO:3002660 APH(6)-Id APH(6)-Id is an aminoglycoside phosphotransferase encoded by plasmids, integrative conjugative elements and chromosomal genomic islands in K. pneumoniae, Salmonella spp., E. coli, Shigella flexneri, Providencia alcalifaciens, Pseudomonas spp., V. cholerae, Edwardsiella tarda, Pasteurella multocida and Aeromonas bestiarum. APH(6) 99.6 1.07e-205 1 278 1.0 1 aminoglycoside antibiotic antibiotic inactivation 517 M0116678 NZ_MN961670.1 NAFPHALK_00246 NZ_MN961670.1__NAFPHALK_00246 NZ_MN961670.1 C1383 NAFPHALK_00246 ARO:3002660 APH(6)-Id APH(6)-Id is an aminoglycoside phosphotransferase encoded by plasmids, integrative conjugative elements and chromosomal genomic islands in K. pneumoniae, Salmonella spp., E. coli, Shigella flexneri, Providencia alcalifaciens, Pseudomonas spp., V. cholerae, Edwardsiella tarda, Pasteurella multocida and Aeromonas bestiarum. APH(6) 99.6 1.07e-205 1 278 1.0 1 aminoglycoside antibiotic antibiotic inactivation 518 M0141323 CP103138.1 IMCFKEJM_00004 CP103138.1__IMCFKEJM_00004 CP103138.1 C182 IMCFKEJM_00004 ARO:3003002 CfxA2 CfxA2 beta-lactamase is a class A beta-lactamase found in Prevotella intermedia. CfxA beta-lactamase 100 2.22e-231 1 321 1.0 1 cephalosporin antibiotic inactivation 519 M0143175 CP012668.1 FOFGEEAJ_00040 CP012668.1__FOFGEEAJ_00040 CP012668.1 C58 FOFGEEAJ_00040 ARO:3002639 APH(3'')-Ib APH(3'')-Ib is an aminoglycoside phosphotransferase encoded by plasmids, transposons, integrative conjugative elements and chromosomes in Enterobacteriaceae and Pseudomonas spp. APH(3'') 99.6 5.98e-202 1 267 1.0 1 aminoglycoside antibiotic antibiotic inactivation 520 M0143680 CP033372.1 FEOLHBOC_00168 CP033372.1__FEOLHBOC_00168 CP033372.1 C77 FEOLHBOC_00168 ARO:3007527 Bacillus subtilis rpsE mutations conferring resistance to spectinomycin Amino acid substitutions in ribosomal protein S5, rpsE, is associated with resistance to spectinomycin (SpcR). spectinomycin resistant rpsE 71.4 2.45e-79 7 167 0.9526627218934911 0.969879518072289 aminoglycoside antibiotic antibiotic target alteration 521 M0144796 CP077245.1 ANDJCPDL_00030 CP077245.1__ANDJCPDL_00030 CP077245.1 C125 ANDJCPDL_00030 ARO:3000873 TEM-1 TEM-1 is a broad-spectrum beta-lactamase found in many Gram-negative bacteria. Confers resistance to penicillins and first generation cephalosphorins. TEM beta-lactamase 100 5.12e-208 1 286 1.0 1 monobactam antibiotic inactivation 522 M0145880 CP093089.1 JMPCBMOH_00009 CP093089.1__JMPCBMOH_00009 CP093089.1 C162 JMPCBMOH_00009 ARO:3004114 porin OmpC In the presence of antibiotic stress, there is a coupled down-regulation of the porin OmpC with the OmpF. Mutants both lacking both OmpC and OmpF proteins are resistant to cephaloridine and cefazolin. Analyses of genes involved in the increased resistance to tetracycline suggest that the up-regulation of efflux pump genes is accompanied by a decrease of OmpF and OmpC synthesis. Homologs of OmpC have been identified in Escherichia coli, Salmonella enterica, Klebsiella aerogenes and Serratia marcescens. General Bacterial Porin with reduced permeability to beta-lactams 80.7 3.31e-220 8 369 0.981029810298103 0.986376021798365 monobactam reduced permeability to antibiotic 523 M0150547 LR962838.1 LGNKMOIG_00016 LR962838.1__LGNKMOIG_00016 LR962838.1 C267 LGNKMOIG_00016 ARO:3000190 tet(O) Tet(O) is a ribosomal protection protein. It is associated with conjugative plasmids. tetracycline-resistant ribosomal protection protein 99.4 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 524 M0151148 NC_006134.1 HPGPFJHI_00001 NC_006134.1__HPGPFJHI_00001 NC_006134.1 C281 HPGPFJHI_00001 ARO:3007120 tet(O/M/O) Tet(O/M/O) is a mosaic tetracycline resistance gene and ribosomal protection protein. tetracycline-resistant ribosomal protection protein 100 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 525 M0151424 NC_010864.1 NGNEIIGH_00007 NC_010864.1__NGNEIIGH_00007 NC_010864.1 C297 NGNEIIGH_00007 ARO:3000375 ErmB ErmB confers the MLSb phenotype. Similar to ErmC, expression of ErmB is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present, it binds the leader peptide causing a change in conformation allowing for the expression of ErmB. Erm 23S ribosomal RNA methyltransferase 97.1 5.38e-172 1 245 1.0 0.987903225806452 macrolide antibiotic antibiotic target alteration 526 M0151425 NC_010864.1 NGNEIIGH_00007 NC_010864.1__NGNEIIGH_00007 NC_010864.1 C297 NGNEIIGH_00007 ARO:3000375 ErmB ErmB confers the MLSb phenotype. Similar to ErmC, expression of ErmB is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present, it binds the leader peptide causing a change in conformation allowing for the expression of ErmB. Erm 23S ribosomal RNA methyltransferase 97.1 5.38e-172 1 245 1.0 0.987903225806452 macrolide antibiotic antibiotic target alteration 527 M0151426 NC_010864.1 NGNEIIGH_00007 NC_010864.1__NGNEIIGH_00007 NC_010864.1 C297 NGNEIIGH_00007 ARO:3000375 ErmB ErmB confers the MLSb phenotype. Similar to ErmC, expression of ErmB is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present, it binds the leader peptide causing a change in conformation allowing for the expression of ErmB. Erm 23S ribosomal RNA methyltransferase 97.1 5.38e-172 1 245 1.0 0.987903225806452 macrolide antibiotic antibiotic target alteration 528 M0151427 NC_010864.1 NGNEIIGH_00007 NC_010864.1__NGNEIIGH_00007 NC_010864.1 C297 NGNEIIGH_00007 ARO:3000375 ErmB ErmB confers the MLSb phenotype. Similar to ErmC, expression of ErmB is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present, it binds the leader peptide causing a change in conformation allowing for the expression of ErmB. Erm 23S ribosomal RNA methyltransferase 97.1 5.38e-172 1 245 1.0 0.987903225806452 macrolide antibiotic antibiotic target alteration 529 M0151428 NC_010864.1 NGNEIIGH_00007 NC_010864.1__NGNEIIGH_00007 NC_010864.1 C297 NGNEIIGH_00007 ARO:3000375 ErmB ErmB confers the MLSb phenotype. Similar to ErmC, expression of ErmB is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present, it binds the leader peptide causing a change in conformation allowing for the expression of ErmB. Erm 23S ribosomal RNA methyltransferase 97.1 5.38e-172 1 245 1.0 0.987903225806452 macrolide antibiotic antibiotic target alteration 530 M0151429 NC_010864.1 NGNEIIGH_00007 NC_010864.1__NGNEIIGH_00007 NC_010864.1 C297 NGNEIIGH_00007 ARO:3000375 ErmB ErmB confers the MLSb phenotype. Similar to ErmC, expression of ErmB is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present, it binds the leader peptide causing a change in conformation allowing for the expression of ErmB. Erm 23S ribosomal RNA methyltransferase 97.1 5.38e-172 1 245 1.0 0.987903225806452 macrolide antibiotic antibiotic target alteration 531 M0151430 NC_010864.1 NGNEIIGH_00007 NC_010864.1__NGNEIIGH_00007 NC_010864.1 C297 NGNEIIGH_00007 ARO:3000375 ErmB ErmB confers the MLSb phenotype. Similar to ErmC, expression of ErmB is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present, it binds the leader peptide causing a change in conformation allowing for the expression of ErmB. Erm 23S ribosomal RNA methyltransferase 97.1 5.38e-172 1 245 1.0 0.987903225806452 macrolide antibiotic antibiotic target alteration 532 M0151431 NC_010864.1 NGNEIIGH_00007 NC_010864.1__NGNEIIGH_00007 NC_010864.1 C297 NGNEIIGH_00007 ARO:3000375 ErmB ErmB confers the MLSb phenotype. Similar to ErmC, expression of ErmB is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present, it binds the leader peptide causing a change in conformation allowing for the expression of ErmB. Erm 23S ribosomal RNA methyltransferase 97.1 5.38e-172 1 245 1.0 0.987903225806452 macrolide antibiotic antibiotic target alteration 533 M0151868 NC_011642.1 CKJDBIGE_00032 NC_011642.1__CKJDBIGE_00032 NC_011642.1 C301 CKJDBIGE_00032 ARO:3002921 vanR gene in vanB cluster Also known as vanRB, is a vanR variant found in the vanB gene cluster. glycopeptide resistance gene cluster 96.3 9.03e-153 1 219 1.0 0.995454545454545 glycopeptide antibiotic antibiotic target alteration 534 M0152813 NC_013514.1 HOPLBKEO_00007 NC_013514.1__HOPLBKEO_00007 NC_013514.1 C313 HOPLBKEO_00007 ARO:3000375 ErmB ErmB confers the MLSb phenotype. Similar to ErmC, expression of ErmB is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present, it binds the leader peptide causing a change in conformation allowing for the expression of ErmB. Erm 23S ribosomal RNA methyltransferase 98.8 9.7e-175 1 245 1.0 0.987903225806452 macrolide antibiotic antibiotic target alteration 535 M0153041 NC_016009.1 AMEBNNJI_00003 NC_016009.1__AMEBNNJI_00003 NC_016009.1 C322 AMEBNNJI_00003 ARO:3000179 tet(L) TetL is a tetracycline efflux protein found in many species of Gram-negative and Gram-positive bacteria. major facilitator superfamily (MFS) antibiotic efflux pump 99.8 3.68e-296 1 428 1.0 0.934497816593886 tetracycline antibiotic antibiotic efflux 536 M0153042 NC_016009.1 AMEBNNJI_00003 NC_016009.1__AMEBNNJI_00003 NC_016009.1 C322 AMEBNNJI_00003 ARO:3000179 tet(L) TetL is a tetracycline efflux protein found in many species of Gram-negative and Gram-positive bacteria. major facilitator superfamily (MFS) antibiotic efflux pump 99.8 3.68e-296 1 428 1.0 0.934497816593886 tetracycline antibiotic antibiotic efflux 537 M0153043 NC_016009.1 AMEBNNJI_00003 NC_016009.1__AMEBNNJI_00003 NC_016009.1 C322 AMEBNNJI_00003 ARO:3000179 tet(L) TetL is a tetracycline efflux protein found in many species of Gram-negative and Gram-positive bacteria. major facilitator superfamily (MFS) antibiotic efflux pump 99.8 3.68e-296 1 428 1.0 0.934497816593886 tetracycline antibiotic antibiotic efflux 538 M0153180 NC_017472.1 MMPBIFCO_00058 NC_017472.1__MMPBIFCO_00058 NC_017472.1 C326 MMPBIFCO_00058 ARO:3000194 tet(W) Tet(W) is a ribosomal protection protein. It is associated with both conjugative and non conjugative DNA and has been found strains of Clostridioides difficile. tetracycline-resistant ribosomal protection protein 97 0 1 638 0.9937694704049844 0.998435054773083 tetracycline antibiotic antibiotic target protection 539 M0153181 NC_017472.1 MMPBIFCO_00058 NC_017472.1__MMPBIFCO_00058 NC_017472.1 C326 MMPBIFCO_00058 ARO:3000194 tet(W) Tet(W) is a ribosomal protection protein. It is associated with both conjugative and non conjugative DNA and has been found strains of Clostridioides difficile. tetracycline-resistant ribosomal protection protein 97 0 1 638 0.9937694704049844 0.998435054773083 tetracycline antibiotic antibiotic target protection 540 M0153182 NC_017472.1 MMPBIFCO_00058 NC_017472.1__MMPBIFCO_00058 NC_017472.1 C326 MMPBIFCO_00058 ARO:3000194 tet(W) Tet(W) is a ribosomal protection protein. It is associated with both conjugative and non conjugative DNA and has been found strains of Clostridioides difficile. tetracycline-resistant ribosomal protection protein 97 0 1 638 0.9937694704049844 0.998435054773083 tetracycline antibiotic antibiotic target protection 541 M0153183 NC_017472.1 MMPBIFCO_00058 NC_017472.1__MMPBIFCO_00058 NC_017472.1 C326 MMPBIFCO_00058 ARO:3000194 tet(W) Tet(W) is a ribosomal protection protein. It is associated with both conjugative and non conjugative DNA and has been found strains of Clostridioides difficile. tetracycline-resistant ribosomal protection protein 97 0 1 638 0.9937694704049844 0.998435054773083 tetracycline antibiotic antibiotic target protection 542 M0153228 NC_018995.1 LFMOKLIM_00044 NC_018995.1__LFMOKLIM_00044 NC_018995.1 C333 LFMOKLIM_00044 ARO:3000873 TEM-1 TEM-1 is a broad-spectrum beta-lactamase found in many Gram-negative bacteria. Confers resistance to penicillins and first generation cephalosphorins. TEM beta-lactamase 100 5.12e-208 1 286 1.0 1 monobactam antibiotic inactivation 543 M0163745 NZ_AP026711.1 CIPPBNBD_00001 NZ_AP026711.1__CIPPBNBD_00001 NZ_AP026711.1 C389 CIPPBNBD_00001 ARO:3000194 tet(W) Tet(W) is a ribosomal protection protein. It is associated with both conjugative and non conjugative DNA and has been found strains of Clostridioides difficile. tetracycline-resistant ribosomal protection protein 100 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 544 M0163746 NZ_AP026711.1 CIPPBNBD_00001 NZ_AP026711.1__CIPPBNBD_00001 NZ_AP026711.1 C389 CIPPBNBD_00001 ARO:3000194 tet(W) Tet(W) is a ribosomal protection protein. It is associated with both conjugative and non conjugative DNA and has been found strains of Clostridioides difficile. tetracycline-resistant ribosomal protection protein 100 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 545 M0163747 NZ_AP026711.1 CIPPBNBD_00001 NZ_AP026711.1__CIPPBNBD_00001 NZ_AP026711.1 C389 CIPPBNBD_00001 ARO:3000194 tet(W) Tet(W) is a ribosomal protection protein. It is associated with both conjugative and non conjugative DNA and has been found strains of Clostridioides difficile. tetracycline-resistant ribosomal protection protein 100 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 546 M0169824 NZ_CP036543.1 OCEPIIIF_00004 NZ_CP036543.1__OCEPIIIF_00004 NZ_CP036543.1 C614 OCEPIIIF_00004 ARO:3007106 nimD nimD is a nitroimidazole reductase mainly found in Bacteroides fragilis that is associated with the deactivation of nitroimidazole antibiotics such as metronidazole. Minimum inhibitory concentrations observed in isolates vary greatly depending on species, strain, and nitroimidazole treatment. nitroimidazole reductase 98.8 2.03e-115 1 164 1.0 1 nitroimidazole antibiotic antibiotic inactivation 547 M0173088 NZ_CP048648.1 MKFDFGGE_00053 NZ_CP048648.1__MKFDFGGE_00053 NZ_CP048648.1 C699 MKFDFGGE_00053 ARO:3000166 tet(B) Tet(B) is a tetracycline efflux protein expressed in many Gram-negative bacteria. It confers resistance to tetracycline, doxycycline, and minocycline, but not tigecycline. major facilitator superfamily (MFS) antibiotic efflux pump 99.3 3.06e-283 1 401 1.0 1 tetracycline antibiotic antibiotic efflux 548 M0173554 NZ_CP051713.1 DECOCAKO_00042 NZ_CP051713.1__DECOCAKO_00042 NZ_CP051713.1 C722 DECOCAKO_00042 ARO:3002660 APH(6)-Id APH(6)-Id is an aminoglycoside phosphotransferase encoded by plasmids, integrative conjugative elements and chromosomal genomic islands in K. pneumoniae, Salmonella spp., E. coli, Shigella flexneri, Providencia alcalifaciens, Pseudomonas spp., V. cholerae, Edwardsiella tarda, Pasteurella multocida and Aeromonas bestiarum. APH(6) 99.6 5.98e-177 15 257 0.9455252918287937 0.87410071942446 aminoglycoside antibiotic antibiotic inactivation 549 M0174016 NZ_CP054002.1 FHFIBDAF_00044 NZ_CP054002.1__FHFIBDAF_00044 NZ_CP054002.1 C739 FHFIBDAF_00044 ARO:3000205 tet(X) Tet(X) is a flavin-dependent monooxygenase conferring resistance to tetracycline antibiotics. Tet(X) hydroxylates position 11a of the tetraketide group thus inactivating the antibiotic. tetracycline inactivation enzyme 99.7 5.98e-288 1 388 1.0 1 glycylcycline antibiotic inactivation 550 M0174017 NZ_CP054002.1 FHFIBDAF_00044 NZ_CP054002.1__FHFIBDAF_00044 NZ_CP054002.1 C739 FHFIBDAF_00044 ARO:3000205 tet(X) Tet(X) is a flavin-dependent monooxygenase conferring resistance to tetracycline antibiotics. Tet(X) hydroxylates position 11a of the tetraketide group thus inactivating the antibiotic. tetracycline inactivation enzyme 99.7 5.98e-288 1 388 1.0 1 glycylcycline antibiotic inactivation 551 M0174018 NZ_CP054002.1 FHFIBDAF_00044 NZ_CP054002.1__FHFIBDAF_00044 NZ_CP054002.1 C739 FHFIBDAF_00044 ARO:3000205 tet(X) Tet(X) is a flavin-dependent monooxygenase conferring resistance to tetracycline antibiotics. Tet(X) hydroxylates position 11a of the tetraketide group thus inactivating the antibiotic. tetracycline inactivation enzyme 99.7 5.98e-288 1 388 1.0 1 glycylcycline antibiotic inactivation 552 M0174019 NZ_CP054002.1 FHFIBDAF_00044 NZ_CP054002.1__FHFIBDAF_00044 NZ_CP054002.1 C739 FHFIBDAF_00044 ARO:3000205 tet(X) Tet(X) is a flavin-dependent monooxygenase conferring resistance to tetracycline antibiotics. Tet(X) hydroxylates position 11a of the tetraketide group thus inactivating the antibiotic. tetracycline inactivation enzyme 99.7 5.98e-288 1 388 1.0 1 glycylcycline antibiotic inactivation 553 M0174020 NZ_CP054002.1 FHFIBDAF_00044 NZ_CP054002.1__FHFIBDAF_00044 NZ_CP054002.1 C739 FHFIBDAF_00044 ARO:3000205 tet(X) Tet(X) is a flavin-dependent monooxygenase conferring resistance to tetracycline antibiotics. Tet(X) hydroxylates position 11a of the tetraketide group thus inactivating the antibiotic. tetracycline inactivation enzyme 99.7 5.98e-288 1 388 1.0 1 glycylcycline antibiotic inactivation 554 M0174021 NZ_CP054002.1 FHFIBDAF_00044 NZ_CP054002.1__FHFIBDAF_00044 NZ_CP054002.1 C739 FHFIBDAF_00044 ARO:3000205 tet(X) Tet(X) is a flavin-dependent monooxygenase conferring resistance to tetracycline antibiotics. Tet(X) hydroxylates position 11a of the tetraketide group thus inactivating the antibiotic. tetracycline inactivation enzyme 99.7 5.98e-288 1 388 1.0 1 glycylcycline antibiotic inactivation 555 M0174022 NZ_CP054002.1 FHFIBDAF_00044 NZ_CP054002.1__FHFIBDAF_00044 NZ_CP054002.1 C739 FHFIBDAF_00044 ARO:3000205 tet(X) Tet(X) is a flavin-dependent monooxygenase conferring resistance to tetracycline antibiotics. Tet(X) hydroxylates position 11a of the tetraketide group thus inactivating the antibiotic. tetracycline inactivation enzyme 99.7 5.98e-288 1 388 1.0 1 glycylcycline antibiotic inactivation 556 M0174036 NZ_CP054002.1 FHFIBDAF_00044 NZ_CP054002.1__FHFIBDAF_00044 NZ_CP054002.1 C739 FHFIBDAF_00044 ARO:3000205 tet(X) Tet(X) is a flavin-dependent monooxygenase conferring resistance to tetracycline antibiotics. Tet(X) hydroxylates position 11a of the tetraketide group thus inactivating the antibiotic. tetracycline inactivation enzyme 99.7 5.98e-288 1 388 1.0 1 glycylcycline antibiotic inactivation 557 M0174037 NZ_CP054002.1 FHFIBDAF_00044 NZ_CP054002.1__FHFIBDAF_00044 NZ_CP054002.1 C739 FHFIBDAF_00044 ARO:3000205 tet(X) Tet(X) is a flavin-dependent monooxygenase conferring resistance to tetracycline antibiotics. Tet(X) hydroxylates position 11a of the tetraketide group thus inactivating the antibiotic. tetracycline inactivation enzyme 99.7 5.98e-288 1 388 1.0 1 glycylcycline antibiotic inactivation 558 M0174154 NZ_CP054002.1 FHFIBDAF_00098 NZ_CP054002.1__FHFIBDAF_00098 NZ_CP054002.1 C739 FHFIBDAF_00098 ARO:3000205 tet(X) Tet(X) is a flavin-dependent monooxygenase conferring resistance to tetracycline antibiotics. Tet(X) hydroxylates position 11a of the tetraketide group thus inactivating the antibiotic. tetracycline inactivation enzyme 99.7 1.47e-222 1 302 1.0 0.778350515463918 glycylcycline antibiotic inactivation 559 M0174155 NZ_CP054002.1 FHFIBDAF_00098 NZ_CP054002.1__FHFIBDAF_00098 NZ_CP054002.1 C739 FHFIBDAF_00098 ARO:3000205 tet(X) Tet(X) is a flavin-dependent monooxygenase conferring resistance to tetracycline antibiotics. Tet(X) hydroxylates position 11a of the tetraketide group thus inactivating the antibiotic. tetracycline inactivation enzyme 99.7 1.47e-222 1 302 1.0 0.778350515463918 glycylcycline antibiotic inactivation 560 M0174156 NZ_CP054002.1 FHFIBDAF_00098 NZ_CP054002.1__FHFIBDAF_00098 NZ_CP054002.1 C739 FHFIBDAF_00098 ARO:3000205 tet(X) Tet(X) is a flavin-dependent monooxygenase conferring resistance to tetracycline antibiotics. Tet(X) hydroxylates position 11a of the tetraketide group thus inactivating the antibiotic. tetracycline inactivation enzyme 99.7 1.47e-222 1 302 1.0 0.778350515463918 glycylcycline antibiotic inactivation 561 M0174157 NZ_CP054002.1 FHFIBDAF_00098 NZ_CP054002.1__FHFIBDAF_00098 NZ_CP054002.1 C739 FHFIBDAF_00098 ARO:3000205 tet(X) Tet(X) is a flavin-dependent monooxygenase conferring resistance to tetracycline antibiotics. Tet(X) hydroxylates position 11a of the tetraketide group thus inactivating the antibiotic. tetracycline inactivation enzyme 99.7 1.47e-222 1 302 1.0 0.778350515463918 glycylcycline antibiotic inactivation 562 M0174172 NZ_CP054002.1 FHFIBDAF_00098 NZ_CP054002.1__FHFIBDAF_00098 NZ_CP054002.1 C739 FHFIBDAF_00098 ARO:3000205 tet(X) Tet(X) is a flavin-dependent monooxygenase conferring resistance to tetracycline antibiotics. Tet(X) hydroxylates position 11a of the tetraketide group thus inactivating the antibiotic. tetracycline inactivation enzyme 99.7 1.47e-222 1 302 1.0 0.778350515463918 glycylcycline antibiotic inactivation 563 M0174173 NZ_CP054002.1 FHFIBDAF_00098 NZ_CP054002.1__FHFIBDAF_00098 NZ_CP054002.1 C739 FHFIBDAF_00098 ARO:3000205 tet(X) Tet(X) is a flavin-dependent monooxygenase conferring resistance to tetracycline antibiotics. Tet(X) hydroxylates position 11a of the tetraketide group thus inactivating the antibiotic. tetracycline inactivation enzyme 99.7 1.47e-222 1 302 1.0 0.778350515463918 glycylcycline antibiotic inactivation 564 M0174291 NZ_CP054002.1 FHFIBDAF_00044 NZ_CP054002.1__FHFIBDAF_00044 NZ_CP054002.1 C739 FHFIBDAF_00044 ARO:3000205 tet(X) Tet(X) is a flavin-dependent monooxygenase conferring resistance to tetracycline antibiotics. Tet(X) hydroxylates position 11a of the tetraketide group thus inactivating the antibiotic. tetracycline inactivation enzyme 99.7 5.98e-288 1 388 1.0 1 glycylcycline antibiotic inactivation 565 M0174306 NZ_CP054002.1 FHFIBDAF_00044 NZ_CP054002.1__FHFIBDAF_00044 NZ_CP054002.1 C739 FHFIBDAF_00044 ARO:3000205 tet(X) Tet(X) is a flavin-dependent monooxygenase conferring resistance to tetracycline antibiotics. Tet(X) hydroxylates position 11a of the tetraketide group thus inactivating the antibiotic. tetracycline inactivation enzyme 99.7 5.98e-288 1 388 1.0 1 glycylcycline antibiotic inactivation 566 M0175147 NZ_CP058300.1 HGBBDPOP_00041 NZ_CP058300.1__HGBBDPOP_00041 NZ_CP058300.1 C759 HGBBDPOP_00041 ARO:3000190 tet(O) Tet(O) is a ribosomal protection protein. It is associated with conjugative plasmids. tetracycline-resistant ribosomal protection protein 100 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 567 M0175148 NZ_CP058300.1 HGBBDPOP_00041 NZ_CP058300.1__HGBBDPOP_00041 NZ_CP058300.1 C759 HGBBDPOP_00041 ARO:3000190 tet(O) Tet(O) is a ribosomal protection protein. It is associated with conjugative plasmids. tetracycline-resistant ribosomal protection protein 100 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 568 M0175149 NZ_CP058300.1 HGBBDPOP_00041 NZ_CP058300.1__HGBBDPOP_00041 NZ_CP058300.1 C759 HGBBDPOP_00041 ARO:3000190 tet(O) Tet(O) is a ribosomal protection protein. It is associated with conjugative plasmids. tetracycline-resistant ribosomal protection protein 100 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 569 M0175150 NZ_CP058300.1 HGBBDPOP_00041 NZ_CP058300.1__HGBBDPOP_00041 NZ_CP058300.1 C759 HGBBDPOP_00041 ARO:3000190 tet(O) Tet(O) is a ribosomal protection protein. It is associated with conjugative plasmids. tetracycline-resistant ribosomal protection protein 100 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 570 M0175151 NZ_CP058300.1 HGBBDPOP_00041 NZ_CP058300.1__HGBBDPOP_00041 NZ_CP058300.1 C759 HGBBDPOP_00041 ARO:3000190 tet(O) Tet(O) is a ribosomal protection protein. It is associated with conjugative plasmids. tetracycline-resistant ribosomal protection protein 100 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 571 M0175152 NZ_CP058300.1 HGBBDPOP_00041 NZ_CP058300.1__HGBBDPOP_00041 NZ_CP058300.1 C759 HGBBDPOP_00041 ARO:3000190 tet(O) Tet(O) is a ribosomal protection protein. It is associated with conjugative plasmids. tetracycline-resistant ribosomal protection protein 100 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 572 M0175153 NZ_CP058300.1 HGBBDPOP_00041 NZ_CP058300.1__HGBBDPOP_00041 NZ_CP058300.1 C759 HGBBDPOP_00041 ARO:3000190 tet(O) Tet(O) is a ribosomal protection protein. It is associated with conjugative plasmids. tetracycline-resistant ribosomal protection protein 100 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 573 M0175154 NZ_CP058300.1 HGBBDPOP_00041 NZ_CP058300.1__HGBBDPOP_00041 NZ_CP058300.1 C759 HGBBDPOP_00041 ARO:3000190 tet(O) Tet(O) is a ribosomal protection protein. It is associated with conjugative plasmids. tetracycline-resistant ribosomal protection protein 100 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 574 M0175155 NZ_CP058300.1 HGBBDPOP_00041 NZ_CP058300.1__HGBBDPOP_00041 NZ_CP058300.1 C759 HGBBDPOP_00041 ARO:3000190 tet(O) Tet(O) is a ribosomal protection protein. It is associated with conjugative plasmids. tetracycline-resistant ribosomal protection protein 100 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 575 M0175156 NZ_CP058300.1 HGBBDPOP_00041 NZ_CP058300.1__HGBBDPOP_00041 NZ_CP058300.1 C759 HGBBDPOP_00041 ARO:3000190 tet(O) Tet(O) is a ribosomal protection protein. It is associated with conjugative plasmids. tetracycline-resistant ribosomal protection protein 100 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 576 M0175165 NZ_CP058300.1 HGBBDPOP_00041 NZ_CP058300.1__HGBBDPOP_00041 NZ_CP058300.1 C759 HGBBDPOP_00041 ARO:3000190 tet(O) Tet(O) is a ribosomal protection protein. It is associated with conjugative plasmids. tetracycline-resistant ribosomal protection protein 100 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 577 M0175166 NZ_CP058300.1 HGBBDPOP_00041 NZ_CP058300.1__HGBBDPOP_00041 NZ_CP058300.1 C759 HGBBDPOP_00041 ARO:3000190 tet(O) Tet(O) is a ribosomal protection protein. It is associated with conjugative plasmids. tetracycline-resistant ribosomal protection protein 100 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 578 M0175167 NZ_CP058300.1 HGBBDPOP_00041 NZ_CP058300.1__HGBBDPOP_00041 NZ_CP058300.1 C759 HGBBDPOP_00041 ARO:3000190 tet(O) Tet(O) is a ribosomal protection protein. It is associated with conjugative plasmids. tetracycline-resistant ribosomal protection protein 100 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 579 M0175168 NZ_CP058300.1 HGBBDPOP_00041 NZ_CP058300.1__HGBBDPOP_00041 NZ_CP058300.1 C759 HGBBDPOP_00041 ARO:3000190 tet(O) Tet(O) is a ribosomal protection protein. It is associated with conjugative plasmids. tetracycline-resistant ribosomal protection protein 100 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 580 M0175169 NZ_CP058300.1 HGBBDPOP_00041 NZ_CP058300.1__HGBBDPOP_00041 NZ_CP058300.1 C759 HGBBDPOP_00041 ARO:3000190 tet(O) Tet(O) is a ribosomal protection protein. It is associated with conjugative plasmids. tetracycline-resistant ribosomal protection protein 100 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 581 M0175170 NZ_CP058300.1 HGBBDPOP_00041 NZ_CP058300.1__HGBBDPOP_00041 NZ_CP058300.1 C759 HGBBDPOP_00041 ARO:3000190 tet(O) Tet(O) is a ribosomal protection protein. It is associated with conjugative plasmids. tetracycline-resistant ribosomal protection protein 100 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 582 M0175171 NZ_CP058300.1 HGBBDPOP_00041 NZ_CP058300.1__HGBBDPOP_00041 NZ_CP058300.1 C759 HGBBDPOP_00041 ARO:3000190 tet(O) Tet(O) is a ribosomal protection protein. It is associated with conjugative plasmids. tetracycline-resistant ribosomal protection protein 100 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 583 M0175172 NZ_CP058300.1 HGBBDPOP_00041 NZ_CP058300.1__HGBBDPOP_00041 NZ_CP058300.1 C759 HGBBDPOP_00041 ARO:3000190 tet(O) Tet(O) is a ribosomal protection protein. It is associated with conjugative plasmids. tetracycline-resistant ribosomal protection protein 100 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 584 M0175173 NZ_CP058300.1 HGBBDPOP_00041 NZ_CP058300.1__HGBBDPOP_00041 NZ_CP058300.1 C759 HGBBDPOP_00041 ARO:3000190 tet(O) Tet(O) is a ribosomal protection protein. It is associated with conjugative plasmids. tetracycline-resistant ribosomal protection protein 100 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 585 M0177471 NZ_CP060803.1 HAHMPLJO_00002 NZ_CP060803.1__HAHMPLJO_00002 NZ_CP060803.1 C775 HAHMPLJO_00002 ARO:3002919 vanR gene in vanA cluster Also known as vanRA, is a vanR variant found in the vanA gene cluster. glycopeptide resistance gene cluster 100 7.79e-171 1 231 1.0 1 glycopeptide antibiotic antibiotic target alteration 586 M0191496 NZ_CP086563.1 KAEHEGLG_00056 NZ_CP086563.1__KAEHEGLG_00056 NZ_CP086563.1 C971 KAEHEGLG_00056 ARO:3000190 tet(O) Tet(O) is a ribosomal protection protein. It is associated with conjugative plasmids. tetracycline-resistant ribosomal protection protein 99.4 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 587 M0191497 NZ_CP086563.1 KAEHEGLG_00056 NZ_CP086563.1__KAEHEGLG_00056 NZ_CP086563.1 C971 KAEHEGLG_00056 ARO:3000190 tet(O) Tet(O) is a ribosomal protection protein. It is associated with conjugative plasmids. tetracycline-resistant ribosomal protection protein 99.4 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 588 M0191498 NZ_CP086563.1 KAEHEGLG_00056 NZ_CP086563.1__KAEHEGLG_00056 NZ_CP086563.1 C971 KAEHEGLG_00056 ARO:3000190 tet(O) Tet(O) is a ribosomal protection protein. It is associated with conjugative plasmids. tetracycline-resistant ribosomal protection protein 99.4 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 589 M0191765 NZ_CP093227.1 MFMFJONB_00210 NZ_CP093227.1__MFMFJONB_00210 NZ_CP093227.1 C1009 MFMFJONB_00210 ARO:3002705 floR floR is a plasmid or chromosome-encoded chloramphenicol exporter that is found in Bordetella bronchiseptica, Escherichia coli, Klebsiella pneumoniae, Salmonella enterica subsp. enterica serovar Typhimurium str. DT104 and Vibrio cholerae. major facilitator superfamily (MFS) antibiotic efflux pump 99.3 4.61e-275 1 404 1.0 1 phenicol antibiotic antibiotic efflux 590 M0191766 NZ_CP093227.1 MFMFJONB_00210 NZ_CP093227.1__MFMFJONB_00210 NZ_CP093227.1 C1009 MFMFJONB_00210 ARO:3002705 floR floR is a plasmid or chromosome-encoded chloramphenicol exporter that is found in Bordetella bronchiseptica, Escherichia coli, Klebsiella pneumoniae, Salmonella enterica subsp. enterica serovar Typhimurium str. DT104 and Vibrio cholerae. major facilitator superfamily (MFS) antibiotic efflux pump 99.3 4.61e-275 1 404 1.0 1 phenicol antibiotic antibiotic efflux 591 M0191767 NZ_CP093227.1 MFMFJONB_00214 NZ_CP093227.1__MFMFJONB_00214 NZ_CP093227.1 C1009 MFMFJONB_00214 ARO:3002639 APH(3'')-Ib APH(3'')-Ib is an aminoglycoside phosphotransferase encoded by plasmids, transposons, integrative conjugative elements and chromosomes in Enterobacteriaceae and Pseudomonas spp. APH(3'') 99.6 5.98e-202 1 267 1.0 1 aminoglycoside antibiotic antibiotic inactivation 592 M0198123 NZ_CP123020.1 DOAFHLFM_00002 NZ_CP123020.1__DOAFHLFM_00002 NZ_CP123020.1 C1154 DOAFHLFM_00002 ARO:3000873 TEM-1 TEM-1 is a broad-spectrum beta-lactamase found in many Gram-negative bacteria. Confers resistance to penicillins and first generation cephalosphorins. TEM beta-lactamase 100 5.12e-208 1 286 1.0 1 monobactam antibiotic inactivation 593 M0199951 NZ_CP136424.1 EAOCOPNJ_00005 NZ_CP136424.1__EAOCOPNJ_00005 NZ_CP136424.1 C1221 EAOCOPNJ_00005 ARO:3000375 ErmB ErmB confers the MLSb phenotype. Similar to ErmC, expression of ErmB is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present, it binds the leader peptide causing a change in conformation allowing for the expression of ErmB. Erm 23S ribosomal RNA methyltransferase 99.1 2.77e-163 1 229 1.0 0.923387096774194 macrolide antibiotic antibiotic target alteration 594 M0199952 NZ_CP136424.1 EAOCOPNJ_00005 NZ_CP136424.1__EAOCOPNJ_00005 NZ_CP136424.1 C1221 EAOCOPNJ_00005 ARO:3000375 ErmB ErmB confers the MLSb phenotype. Similar to ErmC, expression of ErmB is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present, it binds the leader peptide causing a change in conformation allowing for the expression of ErmB. Erm 23S ribosomal RNA methyltransferase 99.1 2.77e-163 1 229 1.0 0.923387096774194 macrolide antibiotic antibiotic target alteration 595 M0199953 NZ_CP136424.1 EAOCOPNJ_00005 NZ_CP136424.1__EAOCOPNJ_00005 NZ_CP136424.1 C1221 EAOCOPNJ_00005 ARO:3000375 ErmB ErmB confers the MLSb phenotype. Similar to ErmC, expression of ErmB is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present, it binds the leader peptide causing a change in conformation allowing for the expression of ErmB. Erm 23S ribosomal RNA methyltransferase 99.1 2.77e-163 1 229 1.0 0.923387096774194 macrolide antibiotic antibiotic target alteration 596 M0199954 NZ_CP136424.1 EAOCOPNJ_00005 NZ_CP136424.1__EAOCOPNJ_00005 NZ_CP136424.1 C1221 EAOCOPNJ_00005 ARO:3000375 ErmB ErmB confers the MLSb phenotype. Similar to ErmC, expression of ErmB is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present, it binds the leader peptide causing a change in conformation allowing for the expression of ErmB. Erm 23S ribosomal RNA methyltransferase 99.1 2.77e-163 1 229 1.0 0.923387096774194 macrolide antibiotic antibiotic target alteration 597 M0199955 NZ_CP136424.1 EAOCOPNJ_00005 NZ_CP136424.1__EAOCOPNJ_00005 NZ_CP136424.1 C1221 EAOCOPNJ_00005 ARO:3000375 ErmB ErmB confers the MLSb phenotype. Similar to ErmC, expression of ErmB is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present, it binds the leader peptide causing a change in conformation allowing for the expression of ErmB. Erm 23S ribosomal RNA methyltransferase 99.1 2.77e-163 1 229 1.0 0.923387096774194 macrolide antibiotic antibiotic target alteration 598 M0199956 NZ_CP136424.1 EAOCOPNJ_00005 NZ_CP136424.1__EAOCOPNJ_00005 NZ_CP136424.1 C1221 EAOCOPNJ_00005 ARO:3000375 ErmB ErmB confers the MLSb phenotype. Similar to ErmC, expression of ErmB is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present, it binds the leader peptide causing a change in conformation allowing for the expression of ErmB. Erm 23S ribosomal RNA methyltransferase 99.1 2.77e-163 1 229 1.0 0.923387096774194 macrolide antibiotic antibiotic target alteration 599 M0199957 NZ_CP136424.1 EAOCOPNJ_00005 NZ_CP136424.1__EAOCOPNJ_00005 NZ_CP136424.1 C1221 EAOCOPNJ_00005 ARO:3000375 ErmB ErmB confers the MLSb phenotype. Similar to ErmC, expression of ErmB is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present, it binds the leader peptide causing a change in conformation allowing for the expression of ErmB. Erm 23S ribosomal RNA methyltransferase 99.1 2.77e-163 1 229 1.0 0.923387096774194 macrolide antibiotic antibiotic target alteration 600 M0199958 NZ_CP136424.1 EAOCOPNJ_00005 NZ_CP136424.1__EAOCOPNJ_00005 NZ_CP136424.1 C1221 EAOCOPNJ_00005 ARO:3000375 ErmB ErmB confers the MLSb phenotype. Similar to ErmC, expression of ErmB is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present, it binds the leader peptide causing a change in conformation allowing for the expression of ErmB. Erm 23S ribosomal RNA methyltransferase 99.1 2.77e-163 1 229 1.0 0.923387096774194 macrolide antibiotic antibiotic target alteration 601 M0199996 NZ_CP136424.1 EAOCOPNJ_00005 NZ_CP136424.1__EAOCOPNJ_00005 NZ_CP136424.1 C1221 EAOCOPNJ_00005 ARO:3000375 ErmB ErmB confers the MLSb phenotype. Similar to ErmC, expression of ErmB is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present, it binds the leader peptide causing a change in conformation allowing for the expression of ErmB. Erm 23S ribosomal RNA methyltransferase 99.1 2.77e-163 1 229 1.0 0.923387096774194 macrolide antibiotic antibiotic target alteration 602 M0199997 NZ_CP136424.1 EAOCOPNJ_00005 NZ_CP136424.1__EAOCOPNJ_00005 NZ_CP136424.1 C1221 EAOCOPNJ_00005 ARO:3000375 ErmB ErmB confers the MLSb phenotype. Similar to ErmC, expression of ErmB is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present, it binds the leader peptide causing a change in conformation allowing for the expression of ErmB. Erm 23S ribosomal RNA methyltransferase 99.1 2.77e-163 1 229 1.0 0.923387096774194 macrolide antibiotic antibiotic target alteration 603 M0199998 NZ_CP136424.1 EAOCOPNJ_00005 NZ_CP136424.1__EAOCOPNJ_00005 NZ_CP136424.1 C1221 EAOCOPNJ_00005 ARO:3000375 ErmB ErmB confers the MLSb phenotype. Similar to ErmC, expression of ErmB is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present, it binds the leader peptide causing a change in conformation allowing for the expression of ErmB. Erm 23S ribosomal RNA methyltransferase 99.1 2.77e-163 1 229 1.0 0.923387096774194 macrolide antibiotic antibiotic target alteration 604 M0201031 NZ_CP143324.1 MFAKMGKK_00030 NZ_CP143324.1__MFAKMGKK_00030 NZ_CP143324.1 C1247 MFAKMGKK_00030 ARO:3002837 lnuC lnuC is a transposon-mediated nucleotidyltransferase found in Streptococcus agalactiae. lincosamide nucleotidyltransferase (LNU) 97.6 1.96e-122 1 164 1.0 1 lincosamide antibiotic antibiotic inactivation 605 M0204921 NZ_CP143951.1 APPIBEKP_00004 NZ_CP143951.1__APPIBEKP_00004 NZ_CP143951.1 C1257 APPIBEKP_00004 ARO:3003097 CfxA6 CfxA6 beta-lactamase is a class A beta-lactamase found in an uncultured bacterium. CfxA beta-lactamase 80.3 2.84e-171 1 315 0.9936908517350158 0.95166163141994 cephalosporin antibiotic inactivation 606 M0204922 NZ_CP143951.1 APPIBEKP_00004 NZ_CP143951.1__APPIBEKP_00004 NZ_CP143951.1 C1257 APPIBEKP_00004 ARO:3003097 CfxA6 CfxA6 beta-lactamase is a class A beta-lactamase found in an uncultured bacterium. CfxA beta-lactamase 80.3 2.84e-171 1 315 0.9936908517350158 0.95166163141994 cephalosporin antibiotic inactivation 607 M0204940 NZ_CP143951.1 APPIBEKP_00004 NZ_CP143951.1__APPIBEKP_00004 NZ_CP143951.1 C1257 APPIBEKP_00004 ARO:3003097 CfxA6 CfxA6 beta-lactamase is a class A beta-lactamase found in an uncultured bacterium. CfxA beta-lactamase 80.3 2.84e-171 1 315 0.9936908517350158 0.95166163141994 cephalosporin antibiotic inactivation 608 M0206820 NZ_LC473083.1 JJMFPJDH_00025 NZ_LC473083.1__JJMFPJDH_00025 NZ_LC473083.1 C1341 JJMFPJDH_00025 ARO:3000194 tet(W) Tet(W) is a ribosomal protection protein. It is associated with both conjugative and non conjugative DNA and has been found strains of Clostridioides difficile. tetracycline-resistant ribosomal protection protein 100 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 609 M0206821 NZ_LC473083.1 JJMFPJDH_00025 NZ_LC473083.1__JJMFPJDH_00025 NZ_LC473083.1 C1341 JJMFPJDH_00025 ARO:3000194 tet(W) Tet(W) is a ribosomal protection protein. It is associated with both conjugative and non conjugative DNA and has been found strains of Clostridioides difficile. tetracycline-resistant ribosomal protection protein 100 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 610 M0206822 NZ_LC473083.1 JJMFPJDH_00025 NZ_LC473083.1__JJMFPJDH_00025 NZ_LC473083.1 C1341 JJMFPJDH_00025 ARO:3000194 tet(W) Tet(W) is a ribosomal protection protein. It is associated with both conjugative and non conjugative DNA and has been found strains of Clostridioides difficile. tetracycline-resistant ribosomal protection protein 100 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 611 M0206823 NZ_LC473083.1 JJMFPJDH_00025 NZ_LC473083.1__JJMFPJDH_00025 NZ_LC473083.1 C1341 JJMFPJDH_00025 ARO:3000194 tet(W) Tet(W) is a ribosomal protection protein. It is associated with both conjugative and non conjugative DNA and has been found strains of Clostridioides difficile. tetracycline-resistant ribosomal protection protein 100 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 612 M0206824 NZ_LC473083.1 JJMFPJDH_00025 NZ_LC473083.1__JJMFPJDH_00025 NZ_LC473083.1 C1341 JJMFPJDH_00025 ARO:3000194 tet(W) Tet(W) is a ribosomal protection protein. It is associated with both conjugative and non conjugative DNA and has been found strains of Clostridioides difficile. tetracycline-resistant ribosomal protection protein 100 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 613 M0206825 NZ_LC473083.1 JJMFPJDH_00025 NZ_LC473083.1__JJMFPJDH_00025 NZ_LC473083.1 C1341 JJMFPJDH_00025 ARO:3000194 tet(W) Tet(W) is a ribosomal protection protein. It is associated with both conjugative and non conjugative DNA and has been found strains of Clostridioides difficile. tetracycline-resistant ribosomal protection protein 100 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 614 M0206826 NZ_LC473083.1 JJMFPJDH_00025 NZ_LC473083.1__JJMFPJDH_00025 NZ_LC473083.1 C1341 JJMFPJDH_00025 ARO:3000194 tet(W) Tet(W) is a ribosomal protection protein. It is associated with both conjugative and non conjugative DNA and has been found strains of Clostridioides difficile. tetracycline-resistant ribosomal protection protein 100 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 615 M0206827 NZ_LC473083.1 JJMFPJDH_00025 NZ_LC473083.1__JJMFPJDH_00025 NZ_LC473083.1 C1341 JJMFPJDH_00025 ARO:3000194 tet(W) Tet(W) is a ribosomal protection protein. It is associated with both conjugative and non conjugative DNA and has been found strains of Clostridioides difficile. tetracycline-resistant ribosomal protection protein 100 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 616 M0206828 NZ_LC473083.1 JJMFPJDH_00025 NZ_LC473083.1__JJMFPJDH_00025 NZ_LC473083.1 C1341 JJMFPJDH_00025 ARO:3000194 tet(W) Tet(W) is a ribosomal protection protein. It is associated with both conjugative and non conjugative DNA and has been found strains of Clostridioides difficile. tetracycline-resistant ribosomal protection protein 100 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 617 M0206829 NZ_LC473083.1 JJMFPJDH_00025 NZ_LC473083.1__JJMFPJDH_00025 NZ_LC473083.1 C1341 JJMFPJDH_00025 ARO:3000194 tet(W) Tet(W) is a ribosomal protection protein. It is associated with both conjugative and non conjugative DNA and has been found strains of Clostridioides difficile. tetracycline-resistant ribosomal protection protein 100 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 618 M0207041 NZ_LR135334.1 GMLELPKF_00006 NZ_LR135334.1__GMLELPKF_00006 NZ_LR135334.1 C1349 GMLELPKF_00006 ARO:3004629 AAC(6')-Im AAC(6')-Im is an aminoglycoside acetyltransferase encoded by plasmids in E. coli, and E. faecium. AAC(6') 100 5.08e-134 1 178 1.0 1 aminoglycoside antibiotic antibiotic inactivation 619 M0207042 NZ_LR135334.1 GMLELPKF_00006 NZ_LR135334.1__GMLELPKF_00006 NZ_LR135334.1 C1349 GMLELPKF_00006 ARO:3004629 AAC(6')-Im AAC(6')-Im is an aminoglycoside acetyltransferase encoded by plasmids in E. coli, and E. faecium. AAC(6') 100 5.08e-134 1 178 1.0 1 aminoglycoside antibiotic antibiotic inactivation 620 M0207043 NZ_LR135334.1 GMLELPKF_00006 NZ_LR135334.1__GMLELPKF_00006 NZ_LR135334.1 C1349 GMLELPKF_00006 ARO:3004629 AAC(6')-Im AAC(6')-Im is an aminoglycoside acetyltransferase encoded by plasmids in E. coli, and E. faecium. AAC(6') 100 5.08e-134 1 178 1.0 1 aminoglycoside antibiotic antibiotic inactivation 621 M0207044 NZ_LR135334.1 GMLELPKF_00007 NZ_LR135334.1__GMLELPKF_00007 NZ_LR135334.1 C1349 GMLELPKF_00007 ARO:3002635 APH(2'')-IIa APH(2'')-IIa is a chromosomal-encoded aminoglycoside phosphotransferase in E. faecium and E. coli. APH(2'') 99.7 7.34e-219 1 299 1.0 1 aminoglycoside antibiotic antibiotic inactivation 622 M0207045 NZ_LR135334.1 GMLELPKF_00007 NZ_LR135334.1__GMLELPKF_00007 NZ_LR135334.1 C1349 GMLELPKF_00007 ARO:3002635 APH(2'')-IIa APH(2'')-IIa is a chromosomal-encoded aminoglycoside phosphotransferase in E. faecium and E. coli. APH(2'') 99.7 7.34e-219 1 299 1.0 1 aminoglycoside antibiotic antibiotic inactivation 623 M0208486 NZ_MG764548.1 MOMMDNLK_00029 NZ_MG764548.1__MOMMDNLK_00029 NZ_MG764548.1 C1374 MOMMDNLK_00029 ARO:3002705 floR floR is a plasmid or chromosome-encoded chloramphenicol exporter that is found in Bordetella bronchiseptica, Escherichia coli, Klebsiella pneumoniae, Salmonella enterica subsp. enterica serovar Typhimurium str. DT104 and Vibrio cholerae. major facilitator superfamily (MFS) antibiotic efflux pump 99.3 4.61e-275 1 404 1.0 1 phenicol antibiotic antibiotic efflux 624 M0208487 NZ_MG764548.1 MOMMDNLK_00029 NZ_MG764548.1__MOMMDNLK_00029 NZ_MG764548.1 C1374 MOMMDNLK_00029 ARO:3002705 floR floR is a plasmid or chromosome-encoded chloramphenicol exporter that is found in Bordetella bronchiseptica, Escherichia coli, Klebsiella pneumoniae, Salmonella enterica subsp. enterica serovar Typhimurium str. DT104 and Vibrio cholerae. major facilitator superfamily (MFS) antibiotic efflux pump 99.3 4.61e-275 1 404 1.0 1 phenicol antibiotic antibiotic efflux 625 M0208488 NZ_MG764548.1 MOMMDNLK_00033 NZ_MG764548.1__MOMMDNLK_00033 NZ_MG764548.1 C1374 MOMMDNLK_00033 ARO:3002639 APH(3'')-Ib APH(3'')-Ib is an aminoglycoside phosphotransferase encoded by plasmids, transposons, integrative conjugative elements and chromosomes in Enterobacteriaceae and Pseudomonas spp. APH(3'') 99.6 5.98e-202 1 267 1.0 1 aminoglycoside antibiotic antibiotic inactivation 626 M0208905 NZ_OL790811.1 ABOOBNBD_03210 NZ_OL790811.1__ABOOBNBD_03210 NZ_OL790811.1 C1399 ABOOBNBD_03210 ARO:3002639 APH(3'')-Ib APH(3'')-Ib is an aminoglycoside phosphotransferase encoded by plasmids, transposons, integrative conjugative elements and chromosomes in Enterobacteriaceae and Pseudomonas spp. APH(3'') 99.6 5.98e-202 1 267 1.0 1 aminoglycoside antibiotic antibiotic inactivation 627 M0208906 NZ_OL790811.1 ABOOBNBD_03213 NZ_OL790811.1__ABOOBNBD_03213 NZ_OL790811.1 C1399 ABOOBNBD_03213 ARO:3002705 floR floR is a plasmid or chromosome-encoded chloramphenicol exporter that is found in Bordetella bronchiseptica, Escherichia coli, Klebsiella pneumoniae, Salmonella enterica subsp. enterica serovar Typhimurium str. DT104 and Vibrio cholerae. major facilitator superfamily (MFS) antibiotic efflux pump 99.3 1.32e-274 1 404 1.0 1 phenicol antibiotic antibiotic efflux 628 M0208907 NZ_OL790811.1 ABOOBNBD_03213 NZ_OL790811.1__ABOOBNBD_03213 NZ_OL790811.1 C1399 ABOOBNBD_03213 ARO:3002705 floR floR is a plasmid or chromosome-encoded chloramphenicol exporter that is found in Bordetella bronchiseptica, Escherichia coli, Klebsiella pneumoniae, Salmonella enterica subsp. enterica serovar Typhimurium str. DT104 and Vibrio cholerae. major facilitator superfamily (MFS) antibiotic efflux pump 99.3 1.32e-274 1 404 1.0 1 phenicol antibiotic antibiotic efflux 629 M0208908 NZ_OL790812.1 FMIGHEMP_03207 NZ_OL790812.1__FMIGHEMP_03207 NZ_OL790812.1 C1400 FMIGHEMP_03207 ARO:3002639 APH(3'')-Ib APH(3'')-Ib is an aminoglycoside phosphotransferase encoded by plasmids, transposons, integrative conjugative elements and chromosomes in Enterobacteriaceae and Pseudomonas spp. APH(3'') 99.6 5.98e-202 1 267 1.0 1 aminoglycoside antibiotic antibiotic inactivation 630 M0209614 NZ_OX460339.1 LIOMHNDJ_00007 NZ_OX460339.1__LIOMHNDJ_00007 NZ_OX460339.1 C1420 LIOMHNDJ_00007 ARO:3002639 APH(3'')-Ib APH(3'')-Ib is an aminoglycoside phosphotransferase encoded by plasmids, transposons, integrative conjugative elements and chromosomes in Enterobacteriaceae and Pseudomonas spp. APH(3'') 99.6 4.35e-199 1 265 1.0 0.99250936329588 aminoglycoside antibiotic antibiotic inactivation 631 M0211005 NZ_OY754457.1 CIECCDMB_00018 NZ_OY754457.1__CIECCDMB_00018 NZ_OY754457.1 C1445 CIECCDMB_00018 ARO:3000166 tet(B) Tet(B) is a tetracycline efflux protein expressed in many Gram-negative bacteria. It confers resistance to tetracycline, doxycycline, and minocycline, but not tigecycline. major facilitator superfamily (MFS) antibiotic efflux pump 99.3 3.06e-283 1 401 1.0 1 tetracycline antibiotic antibiotic efflux 632 M0211006 NZ_OY754457.1 CIECCDMB_00018 NZ_OY754457.1__CIECCDMB_00018 NZ_OY754457.1 C1445 CIECCDMB_00018 ARO:3000166 tet(B) Tet(B) is a tetracycline efflux protein expressed in many Gram-negative bacteria. It confers resistance to tetracycline, doxycycline, and minocycline, but not tigecycline. major facilitator superfamily (MFS) antibiotic efflux pump 99.3 3.06e-283 1 401 1.0 1 tetracycline antibiotic antibiotic efflux 633 M0211099 OQ553951.1 AIJOJHBD_00004 OQ553951.1__AIJOJHBD_00004 OQ553951.1 C1455 AIJOJHBD_00004 ARO:3000190 tet(O) Tet(O) is a ribosomal protection protein. It is associated with conjugative plasmids. tetracycline-resistant ribosomal protection protein 99.7 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 634 M0211100 OQ553951.1 AIJOJHBD_00004 OQ553951.1__AIJOJHBD_00004 OQ553951.1 C1455 AIJOJHBD_00004 ARO:3000190 tet(O) Tet(O) is a ribosomal protection protein. It is associated with conjugative plasmids. tetracycline-resistant ribosomal protection protein 99.7 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 635 M0211101 OQ553951.1 AIJOJHBD_00004 OQ553951.1__AIJOJHBD_00004 OQ553951.1 C1455 AIJOJHBD_00004 ARO:3000190 tet(O) Tet(O) is a ribosomal protection protein. It is associated with conjugative plasmids. tetracycline-resistant ribosomal protection protein 99.7 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 636 M0211102 OQ553951.1 AIJOJHBD_00004 OQ553951.1__AIJOJHBD_00004 OQ553951.1 C1455 AIJOJHBD_00004 ARO:3000190 tet(O) Tet(O) is a ribosomal protection protein. It is associated with conjugative plasmids. tetracycline-resistant ribosomal protection protein 99.7 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 637 M0211103 OQ553951.1 AIJOJHBD_00004 OQ553951.1__AIJOJHBD_00004 OQ553951.1 C1455 AIJOJHBD_00004 ARO:3000190 tet(O) Tet(O) is a ribosomal protection protein. It is associated with conjugative plasmids. tetracycline-resistant ribosomal protection protein 99.7 0 1 639 1.0 1 tetracycline antibiotic antibiotic target protection 638 M0211131 OV141394.1 ADIKFMHL_00258 OV141394.1__ADIKFMHL_00258 OV141394.1 C1456 ADIKFMHL_00258 ARO:3000873 TEM-1 TEM-1 is a broad-spectrum beta-lactamase found in many Gram-negative bacteria. Confers resistance to penicillins and first generation cephalosphorins. TEM beta-lactamase 100 5.12e-208 1 286 1.0 1 monobactam antibiotic inactivation 639 M0211132 OV141394.1 ADIKFMHL_00258 OV141394.1__ADIKFMHL_00258 OV141394.1 C1456 ADIKFMHL_00258 ARO:3000873 TEM-1 TEM-1 is a broad-spectrum beta-lactamase found in many Gram-negative bacteria. Confers resistance to penicillins and first generation cephalosphorins. TEM beta-lactamase 100 5.12e-208 1 286 1.0 1 monobactam antibiotic inactivation 640 M0211133 OV141394.1 ADIKFMHL_00258 OV141394.1__ADIKFMHL_00258 OV141394.1 C1456 ADIKFMHL_00258 ARO:3000873 TEM-1 TEM-1 is a broad-spectrum beta-lactamase found in many Gram-negative bacteria. Confers resistance to penicillins and first generation cephalosphorins. TEM beta-lactamase 100 5.12e-208 1 286 1.0 1 monobactam antibiotic inactivation 641 M0211134 OV141394.1 ADIKFMHL_00258 OV141394.1__ADIKFMHL_00258 OV141394.1 C1456 ADIKFMHL_00258 ARO:3000873 TEM-1 TEM-1 is a broad-spectrum beta-lactamase found in many Gram-negative bacteria. Confers resistance to penicillins and first generation cephalosphorins. TEM beta-lactamase 100 5.12e-208 1 286 1.0 1 monobactam antibiotic inactivation 642 M0211135 OV141394.1 ADIKFMHL_00258 OV141394.1__ADIKFMHL_00258 OV141394.1 C1456 ADIKFMHL_00258 ARO:3000873 TEM-1 TEM-1 is a broad-spectrum beta-lactamase found in many Gram-negative bacteria. Confers resistance to penicillins and first generation cephalosphorins. TEM beta-lactamase 100 5.12e-208 1 286 1.0 1 monobactam antibiotic inactivation 643 M0211136 OV141394.1 ADIKFMHL_00258 OV141394.1__ADIKFMHL_00258 OV141394.1 C1456 ADIKFMHL_00258 ARO:3000873 TEM-1 TEM-1 is a broad-spectrum beta-lactamase found in many Gram-negative bacteria. Confers resistance to penicillins and first generation cephalosphorins. TEM beta-lactamase 100 5.12e-208 1 286 1.0 1 monobactam antibiotic inactivation 644 M0211137 OV141394.1 ADIKFMHL_00258 OV141394.1__ADIKFMHL_00258 OV141394.1 C1456 ADIKFMHL_00258 ARO:3000873 TEM-1 TEM-1 is a broad-spectrum beta-lactamase found in many Gram-negative bacteria. Confers resistance to penicillins and first generation cephalosphorins. TEM beta-lactamase 100 5.12e-208 1 286 1.0 1 monobactam antibiotic inactivation 645 M0211138 OV141394.1 ADIKFMHL_00258 OV141394.1__ADIKFMHL_00258 OV141394.1 C1456 ADIKFMHL_00258 ARO:3000873 TEM-1 TEM-1 is a broad-spectrum beta-lactamase found in many Gram-negative bacteria. Confers resistance to penicillins and first generation cephalosphorins. TEM beta-lactamase 100 5.12e-208 1 286 1.0 1 monobactam antibiotic inactivation 646 M0211139 OV141394.1 ADIKFMHL_00253 OV141394.1__ADIKFMHL_00253 OV141394.1 C1456 ADIKFMHL_00253 ARO:3001878 CTX-M-15 CTX-M-15 is a beta-lactamase found in the Enterobacteriaceae family. CTX-M beta-lactamase 100 1.15e-202 1 291 1.0 1 cephalosporin antibiotic inactivation